KEGG   Ochotona princeps (American pika): 101522551
Entry
101522551         CDS       T07609                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
opi  Ochotona princeps (American pika)
Pathway
opi00670  One carbon pool by folate
opi00790  Folate biosynthesis
opi01100  Metabolic pathways
opi01240  Biosynthesis of cofactors
opi01523  Antifolate resistance
opi04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:opi00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    101522551 (DHFR)
   00670 One carbon pool by folate
    101522551 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    101522551 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101522551 (DHFR)
Enzymes [BR:opi01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     101522551 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 101522551
NCBI-ProteinID: XP_012782729
LinkDB
Position
11A:complement(2450359..2484324)
AA seq 222 aa
MVRPLNCIVAVSQNMGIGRNGDLPWPPLRNEFKYFQRMTTTSTVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINIVLSRELKEPPPGAHFLAKSLDDALKLIEEPELAERVDMVWIVGGSS
VYKPLAGEARATGGGQPGPRGFRCAQSRRRVSYPEQESWVAEVCTCLARRRGYCPWTRHL
LGEGRVLQAAATGTALRSSSGQPPGVDDSRLVPPALLPWLGE
NT seq 669 nt   +upstreamnt  +downstreamnt
atggtgcgcccgctcaactgcatcgtcgctgtgtcccagaacatgggcatcggcaggaac
ggggacctgccctggcccccgctcaggaatgaattcaagtatttccagagaatgaccaca
acgtccacagtggaaggtaaacagaacctggtgatcatgggtcggaagacctggttctcc
atccccgagaagaatcggcctctgaaggacagaatcaacattgtgctcagcagagaactc
aaggaaccgccaccaggagctcatttccttgcgaagagtctggatgatgccttaaaactc
attgaggagccagagttggcggagagagtggatatggtctggattgtgggcggcagctct
gtttataagccgctggctggagaagcaagagccacagggggcgggcagccgggtccccgc
ggcttccggtgcgcacagtctcggcgccgggtctcctaccctgagcaggagagctgggtt
gcggaggtgtgcacctgcctcgcacggcgccgcggctactgcccttggacgcgccatttg
ctgggagagggccgcgtcttgcaggctgccgccaccgggacagctctccgcagtagctct
gggcagcccccgggcgtggatgacagccgcctcgtcccgccagctttactgccctggctc
ggggagtag

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