KEGG   Ochotona princeps (American pika): 101525561
Entry
101525561         CDS       T07609                                 
Symbol
TNF
Name
(RefSeq) tumor necrosis factor isoform X2
  KO
K03156  tumor necrosis factor superfamily, member 2
Organism
opi  Ochotona princeps (American pika)
Pathway
opi01523  Antifolate resistance
opi04010  MAPK signaling pathway
opi04060  Cytokine-cytokine receptor interaction
opi04061  Viral protein interaction with cytokine and cytokine receptor
opi04064  NF-kappa B signaling pathway
opi04071  Sphingolipid signaling pathway
opi04150  mTOR signaling pathway
opi04210  Apoptosis
opi04217  Necroptosis
opi04350  TGF-beta signaling pathway
opi04380  Osteoclast differentiation
opi04612  Antigen processing and presentation
opi04620  Toll-like receptor signaling pathway
opi04621  NOD-like receptor signaling pathway
opi04622  RIG-I-like receptor signaling pathway
opi04625  C-type lectin receptor signaling pathway
opi04640  Hematopoietic cell lineage
opi04650  Natural killer cell mediated cytotoxicity
opi04657  IL-17 signaling pathway
opi04660  T cell receptor signaling pathway
opi04664  Fc epsilon RI signaling pathway
opi04668  TNF signaling pathway
opi04920  Adipocytokine signaling pathway
opi04930  Type II diabetes mellitus
opi04931  Insulin resistance
opi04932  Non-alcoholic fatty liver disease
opi04933  AGE-RAGE signaling pathway in diabetic complications
opi04936  Alcoholic liver disease
opi04940  Type I diabetes mellitus
opi05010  Alzheimer disease
opi05014  Amyotrophic lateral sclerosis
opi05020  Prion disease
opi05022  Pathways of neurodegeneration - multiple diseases
opi05132  Salmonella infection
opi05133  Pertussis
opi05134  Legionellosis
opi05135  Yersinia infection
opi05140  Leishmaniasis
opi05142  Chagas disease
opi05143  African trypanosomiasis
opi05144  Malaria
opi05145  Toxoplasmosis
opi05146  Amoebiasis
opi05152  Tuberculosis
opi05160  Hepatitis C
opi05161  Hepatitis B
opi05163  Human cytomegalovirus infection
opi05164  Influenza A
opi05165  Human papillomavirus infection
opi05166  Human T-cell leukemia virus 1 infection
opi05168  Herpes simplex virus 1 infection
opi05169  Epstein-Barr virus infection
opi05170  Human immunodeficiency virus 1 infection
opi05171  Coronavirus disease - COVID-19
opi05205  Proteoglycans in cancer
opi05310  Asthma
opi05321  Inflammatory bowel disease
opi05322  Systemic lupus erythematosus
opi05323  Rheumatoid arthritis
opi05330  Allograft rejection
opi05332  Graft-versus-host disease
opi05410  Hypertrophic cardiomyopathy
opi05414  Dilated cardiomyopathy
opi05417  Lipid and atherosclerosis
opi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:opi00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101525561 (TNF)
   04350 TGF-beta signaling pathway
    101525561 (TNF)
   04064 NF-kappa B signaling pathway
    101525561 (TNF)
   04668 TNF signaling pathway
    101525561 (TNF)
   04071 Sphingolipid signaling pathway
    101525561 (TNF)
   04150 mTOR signaling pathway
    101525561 (TNF)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    101525561 (TNF)
   04061 Viral protein interaction with cytokine and cytokine receptor
    101525561 (TNF)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    101525561 (TNF)
   04217 Necroptosis
    101525561 (TNF)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    101525561 (TNF)
   04620 Toll-like receptor signaling pathway
    101525561 (TNF)
   04621 NOD-like receptor signaling pathway
    101525561 (TNF)
   04622 RIG-I-like receptor signaling pathway
    101525561 (TNF)
   04625 C-type lectin receptor signaling pathway
    101525561 (TNF)
   04650 Natural killer cell mediated cytotoxicity
    101525561 (TNF)
   04612 Antigen processing and presentation
    101525561 (TNF)
   04660 T cell receptor signaling pathway
    101525561 (TNF)
   04657 IL-17 signaling pathway
    101525561 (TNF)
   04664 Fc epsilon RI signaling pathway
    101525561 (TNF)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    101525561 (TNF)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101525561 (TNF)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    101525561 (TNF)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101525561 (TNF)
   05170 Human immunodeficiency virus 1 infection
    101525561 (TNF)
   05161 Hepatitis B
    101525561 (TNF)
   05160 Hepatitis C
    101525561 (TNF)
   05171 Coronavirus disease - COVID-19
    101525561 (TNF)
   05164 Influenza A
    101525561 (TNF)
   05168 Herpes simplex virus 1 infection
    101525561 (TNF)
   05163 Human cytomegalovirus infection
    101525561 (TNF)
   05169 Epstein-Barr virus infection
    101525561 (TNF)
   05165 Human papillomavirus infection
    101525561 (TNF)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101525561 (TNF)
   05135 Yersinia infection
    101525561 (TNF)
   05133 Pertussis
    101525561 (TNF)
   05134 Legionellosis
    101525561 (TNF)
   05152 Tuberculosis
    101525561 (TNF)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101525561 (TNF)
   05144 Malaria
    101525561 (TNF)
   05145 Toxoplasmosis
    101525561 (TNF)
   05140 Leishmaniasis
    101525561 (TNF)
   05142 Chagas disease
    101525561 (TNF)
   05143 African trypanosomiasis
    101525561 (TNF)
  09163 Immune disease
   05310 Asthma
    101525561 (TNF)
   05322 Systemic lupus erythematosus
    101525561 (TNF)
   05323 Rheumatoid arthritis
    101525561 (TNF)
   05321 Inflammatory bowel disease
    101525561 (TNF)
   05330 Allograft rejection
    101525561 (TNF)
   05332 Graft-versus-host disease
    101525561 (TNF)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101525561 (TNF)
   05014 Amyotrophic lateral sclerosis
    101525561 (TNF)
   05020 Prion disease
    101525561 (TNF)
   05022 Pathways of neurodegeneration - multiple diseases
    101525561 (TNF)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101525561 (TNF)
   05418 Fluid shear stress and atherosclerosis
    101525561 (TNF)
   05410 Hypertrophic cardiomyopathy
    101525561 (TNF)
   05414 Dilated cardiomyopathy
    101525561 (TNF)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101525561 (TNF)
   04940 Type I diabetes mellitus
    101525561 (TNF)
   04936 Alcoholic liver disease
    101525561 (TNF)
   04932 Non-alcoholic fatty liver disease
    101525561 (TNF)
   04931 Insulin resistance
    101525561 (TNF)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101525561 (TNF)
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    101525561 (TNF)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:opi04052]
    101525561 (TNF)
   00536 Glycosaminoglycan binding proteins [BR:opi00536]
    101525561 (TNF)
Cytokines and neuropeptides [BR:opi04052]
 Cytokines
  Tumor necrosis fators
   101525561 (TNF)
Glycosaminoglycan binding proteins [BR:opi00536]
 Heparan sulfate / Heparin
  Cytokines
   101525561 (TNF)
SSDB
Motif
Pfam: TNF
Other DBs
NCBI-GeneID: 101525561
NCBI-ProteinID: XP_004598774
LinkDB
Position
12:29724949..29726665
AA seq 232 aa
MSTENMIRDVELAEGQLSKKTEASQGPKRCLCLSLFSFLLVAGATTLFCLLHFGVIGPQG
EEFPNNLHLVNPLAQTLRSASRTPSDKPVAHVVANPQKEGQLEWLNQRANALLANGLKLI
DNQLVVPRDGLYLVYSQVLFKGQACPSYLLLTHTVSRFAVSYPNKVNLLSAIKSPCQKET
PEGTEPMAWYEPIYQGGVFQLEKGDRLSTEVNMPDYLDLAESGQVYFGIIAL
NT seq 699 nt   +upstreamnt  +downstreamnt
atgagcactgaaaacatgatccgggacgtggagctggctgaggggcagctctccaagaag
acagaggcctcccaaggtcccaagcgctgcctgtgtctcagcctcttctccttcttgctt
gtggcgggagccaccacgctcttctgcctgctgcacttcggggtgatcggccctcagggc
gaagagttcccaaacaacctccatctagtcaaccctctggcccagaccctcagatcagct
tctcgcaccccgagtgacaagcccgtagcacacgtagtagcaaacccacaaaaggagggc
cagcttgagtggctgaaccagcgtgctaacgccctcctggccaatggcctgaagctgata
gacaaccagctggtggtgcccagggatgggctctacctcgtctactcccaggtgctcttc
aagggtcaagcctgcccttcctacttgctccttactcacacggtcagccgctttgctgtc
tcctacccgaacaaggtcaacctcctctctgccatcaagagcccctgccagaaggagacc
cccgaagggactgagcccatggcctggtatgagcccatctaccagggtggagtcttccag
ctggagaagggagaccgactcagcaccgaagtcaatatgcccgactatcttgacctggcc
gagtcagggcaggtgtactttggcatcattgccttgtga

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