Ochotona princeps (American pika): 101525667
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Entry
101525667 CDS
T07609
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi04120
Ubiquitin mediated proteolysis
opi04144
Endocytosis
opi04330
Notch signaling pathway
opi04668
TNF signaling pathway
opi04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101525667 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101525667 (ITCH)
04668 TNF signaling pathway
101525667 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101525667 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101525667 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
opi04131
]
101525667 (ITCH)
04121 Ubiquitin system [BR:
opi04121
]
101525667 (ITCH)
Enzymes [BR:
opi01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
101525667 (ITCH)
Membrane trafficking [BR:
opi04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
101525667 (ITCH)
Ubiquitin system [BR:
opi04121
]
Ubiquitin ligases (E3)
HECT type E3
101525667 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
101525667
NCBI-ProteinID:
XP_004585795
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All DBs
Position
4A:21351026..21435057
Genome browser
AA seq
868 aa
AA seq
DB search
MSDSGSQLGSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQSITVIVTPVSKLHFRVWSHQTLKSDVLLGSAALDIYETLKSNNMKLEEVVVTL
QLVGDREPTETVGDLSVCLDGLQLDSEVVTNGETTCSESASQNDDGSRSKEETRVNANGS
DDPEEAGSGEYRRINGNNSPSLSNGGFKPARPPRPSRPPPPTPRRPASVNGSPPATSESD
GSSTGSLQPTSTSTSTNTSTSASEGAASGLIIPLTIAGGAGPRPLNTVAQAPLPPGWEQR
VDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVR
NYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVY
FVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSA
LDNGPQIAYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRR
RLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHL
KYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENN
IEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQ
AFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHTIYRHYTRTSKQIMWFWQF
VKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRL
DLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2607 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttggttcaatgggtagcctgaccatgaaatcacaactg
cagatcactgtcatctcagcaaaactcaaagaaaataaaaagaactggtttggaccaagt
ccttatgtagaagtcacggttgatggacagtcaaagaagacggaaaaatgcaacaatacc
aacagtcccaaatggaagcagtctatcacagttattgttacccctgtgagtaaattacat
tttcgtgtatggagtcaccagacattgaaatctgatgttttattgggaagtgctgcgtta
gatatttatgaaaccttaaagtcgaacaacatgaaacttgaagaagtggttgtgactttg
cagcttgtaggtgacagagagccaacagagacagttggagacttgtcagtgtgtcttgat
gggctgcagttagattccgaggtcgtcactaatggtgaaactacatgttcagaaagtgct
tcacagaacgatgatggctccagatctaaggaggaaacaagagtgaatgcaaatggatca
gatgaccctgaggaggcagggtctggcgaatataggaggatcaatgggaataattctcca
tctctctcaaatggtggttttaaacctgctagaccaccaagaccgtctcgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccacctgctacttctgaaagtgat
ggatccagtacaggttctctgcaaccaacaagtacaagtacaagtacaaacacaagtaca
agtgcatctgaaggagcagcatctggattaataattcctcttaccatagctggaggtgca
ggccctaggccattaaatactgtagctcaagctcccctcccacctggttgggagcagaga
gtggaccagcatgggcgagtttactatgtagatcatgttgaaaaaagaaccacgtgggat
agaccagaacctctacctcctggctgggaacggcgagtggacaacatgggacgtatttat
tatgttgaccattttacaagaacaacaacgtggcagaggccaaccttggaatccgtccgg
aactatgaacagtggcagctacagcgtagtcaacttcaaggagcaatgcagcagttcaac
cagagattcatttatgggaatcaagatttgtttgctacatcacaaaataaagaatttgat
ccccttggtcctttgccacctgggtgggaaaagagaactgacagcaatggcagagtgtat
tttgtcaaccacaacacccgaattacacagtgggaagatccacgaagtcaaggtcagtta
aatgaaaagcccttacctgaaggctgggaaatgaggttcacagtggatggcattccatat
tttgtggaccataacagaagaacaaccacctacatagatcctcgcacaggaaaatctgcc
ctagacaacgggccacagatagcctatgttcgggacttcaaggcaaaggttcagtatttc
cgcttctggtgtcagcaactggccatgccacagcacataaagatcacagtgacaagaaaa
acattgtttgaagattcctttcaacagataatgagcttcagtcctcaggatctgcgaaga
cgtttgtgggtgattttccctggagaagaaggtttagattatggaggtgtagcaagagaa
tggttctttcttttgtcacatgaagtgttgaacccaatgtattgcctgtttgaatatgca
gggaaggataactactgcttgcagataaaccctgcttcttacatcaatccagatcacctg
aaatattttcgctttattgggaggtttattgccatggctctgtttcatgggaaattcata
gacacgggtttctctttaccgttttataaacgtatcttgaacaaaccagttggacttaag
gacttagagtcaatagatcctgaattttataattccctcatctgggttaaagaaaacaat
attgaagaatgtggtttggaaatgtacttctcagttgataaagaaattctgggtgaaatt
aagagtcatgatttgaaaccaaatggtggcaatattcttgtaacagaagaaaataaggag
gaatatatcagaatggtagctgaatggaggttgtctcgaggtgttgaagaacagacacaa
gctttctttgagggctttaatgaaattcttccccagcaatatttgcaatactttgatgca
aaagaattggaggttcttttatgtggaatgcaagagattgatttgaatgattggcaaaga
cacaccatttatcgtcattatactcgaaccagcaaacaaatcatgtggttttggcagttt
gttaaagaaatagataatgagaagagaatgagacttctacagtttgttactggaacctgc
cgattgccagtaggaggatttgctgatctcatggggagcaatggaccacagaaattctgc
attgaaaaagttgggaaagagaactggttacccagaagtcatacatgttttaaccgcctg
gacctgccaccctacaagagctatgagcaattgaaggaaaagttgttgtttgccattgaa
gaaacagaaggatttggacaagagtag
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