Ochotona princeps (American pika): 101527090 Help Entry 101527090         CDS       T07609                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism opi  Ochotona princeps (American pika) Pathway opi04062   Chemokine signaling pathway opi04151   PI3K-Akt signaling pathway opi04217   Necroptosis opi04550   Signaling pathways regulating pluripotency of stem cells opi04630   JAK-STAT signaling pathway opi04658   Th1 and Th2 cell differentiation opi04659   Th17 cell differentiation opi05161   Hepatitis B opi05162   Measles opi05166   Human T-cell leukemia virus 1 infection opi05169   Epstein-Barr virus infection opi05200   Pathways in cancer opi05203   Viral carcinogenesis opi05223   Non-small cell lung cancer opi05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:opi00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     101527090 (JAK3)    04151 PI3K-Akt signaling pathway     101527090 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     101527090 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     101527090 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     101527090 (JAK3)    04659 Th17 cell differentiation     101527090 (JAK3)    04062 Chemokine signaling pathway     101527090 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101527090 (JAK3)    05203 Viral carcinogenesis     101527090 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     101527090 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101527090 (JAK3)    05161 Hepatitis B     101527090 (JAK3)    05162 Measles     101527090 (JAK3)    05169 Epstein-Barr virus infection     101527090 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     101527090 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:opi01001]     101527090 (JAK3) Enzymes [BR:opi01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      101527090 (JAK3) Protein kinases [BR:opi01001]  Non-receptor tyrosine kinases   JAK family [OT]    101527090 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Jak1_Phl ABC1 SH2 APH RIO1 Haspin_kinase Kinase-like DUF7050 Motif Other DBs NCBI-GeneID:  101527090 NCBI-ProteinID:  XP_004595852 LinkDB All DBs Position Unknown AA seq 611 aa AA seqDB search MAPPGEETPLISQRSCSLSSSEAGALHVLLPSRGPGPPQRLSFSFGDHLAEDLCVQAAKA SGILPVYHPLFALATEDLSCWFPPSHVFSVEDSGTQVLFYRLRFYFPDWFGPEKCHRFGL RKELTSAILDLPVLEHLFAQHRSDLLSGRLAVGLSFKEQGECLSLAVLDLARMACEQVQR PNELLQTVSYKACLPPGLRGLIQSLSFVTRRRIRRTVRRALRRVAACGADRHALMVKYLL DLERLAPAGAAETFRVGAQGEAEFPGLPQALSFVALVDGYFRLTADSRHFFCKELAPPRL LQEEAERCHGPITLDFAIHKLKTQGSVPGSYVLRRSPQDFDSFLLTVCVQTPLGPDYKGC LIRRGPTGTFSLAGLGRPHSSLRELLAAYQNGGLHPTSAGRRQSLRLVMEYVPSGCLRDF LQRHRARLDASRLLLYASQICKGMEYLGSCRCVHRDLAARNILVESETHVKIADFGLAKL LPLGKDYYVVREPGQSPIFWYAPESLSDNMFSRQSDVWSFGVLLYELFTYSDKSCSPSAE FLRMMGGERDAPALCRLLELLAEGHRLPAPPACPVEVHELMKLCWAPSPEDRPTFSALGP QLDALWSGSRG NT seq 1836 nt NT seq  +upstreamnt  +downstreamnt atggcacccccgggtgaggagacacccttgatctcccagcgctcctgcagcctctcctcg tccgaggctggcgccttgcatgtgctcctgccctctcgcggccctgggcccccccagcgc ctgtccttctccttcggggaccacctggccgaggacctgtgcgtgcaggccgccaaggcc agtggcatcctgcccgtctaccaccctctgtttgctctggccacggaggacctgtcctgc tggtttcctccaagccatgtcttctccgtggaggactcgggcacccaagtgttgttctac aggctccgtttttacttcccagactggtttgggcctgagaaatgtcaccgcttcgggctc cgcaaagagctgaccagcgccatcttagacctgcccgttttggagcacttgtttgcccag caccgcagtgacttgctcagcgggcgcctggctgtgggcctgagcttcaaggagcagggt gagtgtctgagcctggccgtgctggacctggcgcgcatggcctgcgagcaggtgcaacgg cccaatgagctccttcagaccgtgagctacaaggcctgcctgcccccgggtctgcgcggc ctcatccagagcctgagcttcgtgacgcgccgccgcatccgcaggacggtgcgccgtgcc ctgcgccgcgtggccgcctgcggggcagaccggcacgcgctcatggtcaagtacctgctg gacctggagcgcctggcccccgccggggcggccgagaccttccgcgtcggggcccagggg gaagctgagttccccgggctgccccaggcgctgtccttcgtggcgctggtggacggctac ttccgcctcaccgccgactcccgccacttcttctgcaaggagctggcgccgccgcggctg ctgcaggaggaggccgagcggtgccacggccccatcaccctggacttcgccatccacaag ctgaagacacagggctcggtccctggctcctacgtcctccgccgcagcccgcaggatttt gacagctttctcctcaccgtgtgcgttcagacgcctctcggcccggactacaagggttgc ctgatccggcgcggtcccaccggcaccttttccctggctggccttggccggcctcacagc agcctgcgggagctcctggctgcctaccagaacggggggctgcatcccacctctgctggg cgccgccagagcttgcgtctggtcatggagtacgtgcccagcggctgcctgcgcgacttc ctgcagcgccaccgcgcacgactggacgcctctcgcctcctgctctatgcctcacagatc tgcaagggcatggagtacctgggctcctgccgctgcgtgcaccgggacctggccgcccgc aacatcctggtggagagcgagacccacgtcaaaatcgccgacttcggcctggccaagctg ctgccgctgggcaaggattactatgtggtccgcgagccaggccagagccccatcttctgg tacgcccccgagtccttgtcagacaacatgttctcgcgccagtcagacgtgtggagcttc ggtgtgctgctgtacgaactgttcacctacagcgacaagagctgcagcccctcagctgag ttcctgcggatgatgggaggtgagcgtgatgcccccgccctctgccgcctgctggagctg ctggccgagggtcaccggctgccggcgccgcctgcctgccctgtcgaggttcatgagctc atgaagctctgctgggctcccagccccgaggaccggccgaccttcagtgctctgggcccc cagctggatgcgctgtggagcggaagccgaggctga

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