Entry Name ABC transporters - Anoxybacillus sp. B2M1
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Anoxybacillus sp. B2M1 [GN:
anm ]
Gene GFC28_764 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
GFC28_2208 binding--dependent transport system inner membrane component family protein [KO:K11070 ]
GFC28_2209 binding--dependent transport system inner membrane component family protein [KO:K11071 ]
GFC28_2227 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845 ]
GFC28_2225 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
GFC28_1852 binding--dependent transport system inner membrane component family protein [KO:K15771 ]
GFC28_1851 binding--dependent transport system inner membrane component family protein [KO:K15772 ]
GFC28_944 bacterial extracellular solute-binding family protein [KO:K10117 ]
GFC28_943 binding--dependent transport system inner membrane component family protein [KO:K10118 ]
GFC28_942 binding--dependent transport system inner membrane component family protein [KO:K10119 ]
GFC28_938 bacterial extracellular solute-binding family protein [KO:K17318 ]
GFC28_937 binding--dependent transport system inner membrane component family protein [KO:K17319 ]
GFC28_936 binding--dependent transport system inner membrane component family protein [KO:K17320 ]
GFC28_1890 binding--dependent transport system inner membrane component family protein [KO:K10237 ]
GFC28_1889 binding--dependent transport system inner membrane component family protein [KO:K10238 ]
GFC28_959 branched-chain amino acid transport system / permease component family protein [KO:K10547 ]
GFC28_1170 branched-chain amino acid transport system / permease component family protein [KO:K23535 ]
GFC28_1169 branched-chain amino acid transport system / permease component family protein [KO:K23536 ]
GFC28_271 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
GFC28_951 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
GFC28_2865 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
GFC28_270 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
GFC28_1057 branched-chain amino acid transport system / permease component family protein [KO:K10544 ]
GFC28_343 branched-chain amino acid transport system / permease component family protein [KO:K10560 ]
GFC28_344 branched-chain amino acid transport system / permease component family protein [KO:K10561 ]
GFC28_342 ccmA; heme ABC exporter, ATP-binding protein CcmA [KO:K10562 ] [EC:7.5.2.-]
GFC28_2746 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10037 ]
GFC28_974 bacterial extracellular solute-binding s, 3 family protein [KO:K10039 ]
GFC28_975 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10040 ]
GFC28_976 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10040 ]
GFC28_1928 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
GFC28_1927 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
GFC28_3 bacterial extracellular solute-binding s, 3 family protein [KO:K23059 ]
GFC28_4 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K17077 ]
GFC28_2736 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
GFC28_1470 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
GFC28_1469 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
GFC28_2737 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
GFC28_2739 branched chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
GFC28_3164 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
GFC28_322 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
GFC28_1803 binding--dependent transport system inner membrane component family protein [KO:K15581 ]
GFC28_1802 binding--dependent transport system inner membrane component family protein [KO:K15582 ]
GFC28_697 putative multidrug resistance ABC transporter ATP-binding/permease protein YheH [KO:K18890 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
