PATHWAY: babt02010 Help
Entry
Name
ABC transporters - Brucella abortus 63 75
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Brucella abortus 63 75 [GN:
babt ]
Gene
DK49_1080 sulfate ABC transporter, sulfate-binding family protein [KO:K02048 ]
DK49_1974 sulfate ABC transporter, sulfate-binding family protein [KO:K23163 ]
DK49_2097 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DK49_2375 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DK49_2071 binding--dependent transport system inner membrane component family protein [KO:K15599 ]
DK49_2195 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
DK49_2720 bacterial extracellular solute-binding family protein [KO:K02012 ]
DK49_2741 bacterial extracellular solute-binding family protein [KO:K02012 ]
DK49_2719 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
DK49_2740 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
DK49_1473 thiB; thiamin/thiamine pyrophosphate ABC transporter, thiamin/thiamine pyrophospate-binding protein [KO:K02064 ]
DK49_1474 thiP; thiamine/thiamine pyrophosphate ABC transporter, permease protein [KO:K02063 ]
DK49_1336 bacterial extracellular solute-binding family protein [KO:K11073 ]
DK49_1332 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
DK49_1334 putative spermidine/putrescine ABC transporter, permease component I protein [KO:K11075 ]
DK49_3102 bacterial extracellular solute-binding family protein [KO:K11077 ]
DK49_3103 binding--dependent transport system inner membrane component family protein [KO:K11078 ]
DK49_3104 binding--dependent transport system inner membrane component family protein [KO:K11079 ]
DK49_1304 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
DK49_2755 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
DK49_2756 binding--dependent transport system inner membrane component family protein [KO:K02001 ]
DK49_4 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845 ]
DK49_3 putative osmoprotectant uptake system permease protein yehY [KO:K05846 ]
DK49_2082 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
DK49_2551 bacterial extracellular solute-binding family protein [KO:K10117 ]
DK49_2552 binding--dependent transport system inner membrane component family protein [KO:K10118 ]
DK49_2553 binding--dependent transport system inner membrane component family protein [KO:K10119 ]
DK49_2392 bacterial extracellular solute-binding family protein [KO:K10236 ]
DK49_2393 binding--dependent transport system inner membrane component family protein [KO:K10237 ]
DK49_2394 binding--dependent transport system inner membrane component family protein [KO:K10238 ]
DK49_2941 sbpA; multiple sugar-binding periplasmic protein sbpA [KO:K10546 ]
DK49_2939 branched-chain amino acid transport system / permease component family protein [KO:K10547 ]
DK49_2120 branched-chain amino acid transport system / permease component family protein [KO:K23535 ]
DK49_2597 branched-chain amino acid transport system / permease component family protein [KO:K23535 ]
DK49_2119 branched-chain amino acid transport system / permease component family protein [KO:K23536 ]
DK49_2596 branched-chain amino acid transport system / permease component family protein [KO:K23536 ]
DK49_2712 binding--dependent transport system inner membrane component family protein [KO:K17316 ]
DK49_2711 binding--dependent transport system inner membrane component family protein [KO:K17317 ]
DK49_333 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DK49_2997 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DK49_332 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DK49_2994 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DK49_2995 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DK49_2356 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10543 ]
DK49_3153 xylF; D-xylose ABC transporter, D-xylose-binding protein [KO:K10543 ]
DK49_2358 branched-chain amino acid transport system / permease component family protein [KO:K10544 ]
DK49_3155 branched-chain amino acid transport system / permease component family protein [KO:K10544 ]
DK49_2866 periplasmic binding s and sugar binding domain of LacI family protein [KO:K17202 ]
DK49_2867 branched-chain amino acid transport system / permease component family protein [KO:K17203 ]
DK49_1357 periplasmic binding s and sugar binding domain of LacI family protein [KO:K17205 ]
DK49_1358 branched-chain amino acid transport system / permease component family protein [KO:K17206 ]
DK49_2682 bacterial extracellular solute-binding family protein [KO:K05813 ]
DK49_2683 binding--dependent transport system inner membrane component family protein [KO:K05814 ]
DK49_2684 binding--dependent transport system inner membrane component family protein [KO:K05815 ]
DK49_1827 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
DK49_1828 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
DK49_520 bacterial extracellular solute-binding s, 3 family protein [KO:K09969 ]
DK49_2952 bacterial extracellular solute-binding s, 3 family protein [KO:K09969 ]
DK49_521 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K09970 ]
DK49_523 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K09971 ]
DK49_2703 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
DK49_2704 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
DK49_2676 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DK49_1499 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DK49_2455 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DK49_2103 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DK49_2137 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DK49_2960 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DK49_2456 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DK49_2083 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DK49_1498 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DK49_2677 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DK49_2104 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DK49_2138 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DK49_2961 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DK49_2965 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
DK49_2569 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15580 ]
DK49_2570 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15580 ]
DK49_2568 binding--dependent transport system inner membrane component family protein [KO:K15581 ]
DK49_2567 binding--dependent transport system inner membrane component family protein [KO:K15582 ]
DK49_1311 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
DK49_1310 binding--dependent transport system inner membrane component family protein [KO:K12369 ]
DK49_1309 binding--dependent transport system inner membrane component family protein [KO:K12370 ]
DK49_2817 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15584 ]
DK49_2818 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15584 ]
DK49_1881 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
DK49_1882 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
DK49_1880 binding--dependent transport system inner membrane component family protein [KO:K13894 ]
DK49_1879 binding--dependent transport system inner membrane component family protein [KO:K13895 ]
DK49_1111 cobalt uptake substrate-specific transmembrane region family protein [KO:K02007 ]
DK49_596 liporeleasing system, transmembrane , LolC/E family protein [KO:K09808 ]
DK49_1227 ABC transporter transmembrane region 2 family protein [KO:K02471 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
LinkDB
All DBs