PATHWAY: bcs02010 Help
Entry
Name
ABC transporters - Brucella canis ATCC 23365
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Brucella canis ATCC 23365 [GN:
bcs ]
Gene
BCAN_B1217 ABC transporter, substrate-binding protein, aliphatic sulfonates family [KO:K15553 ]
BCAN_B1219 binding-protein-dependent transport systems inner membrane component [KO:K15554 ]
BCAN_B0287 binding-protein-dependent transport systems inner membrane component [KO:K15554 ]
BCAN_A0213 binding-protein-dependent transport systems inner membrane component [KO:K15599 ]
BCAN_B0091 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
BCAN_B0701 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
BCAN_A1796 thiB; thiamin/thiamin pyrophosphate ABC transporter binding protein [KO:K02064 ]
BCAN_A1797 thiP; thiamine/thiamine pyrophosphate ABC transporter, permease protein [KO:K02063 ]
BCAN_A1646 potC; Spermidine/putrescine transport system permease protein potC [KO:K11074 ]
BCAN_A1647 binding-protein-dependent transport systems inner membrane component [KO:K11075 ]
BCAN_A1614 Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
BCAN_B0746 Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
BCAN_B0747 binding-protein-dependent transport systems inner membrane component [KO:K02001 ]
BCAN_A1615 binding-protein-dependent transport systems inner membrane component [KO:K02001 ]
BCAN_A0228 Substrate-binding region of ABC-type glycine betaine transport system [KO:K05845 ]
BCAN_A0225 binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
BCAN_A0227 binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
BCAN_B0688 malK; Maltose/maltodextrin import ATP-binding protein malK [KO:K10112 ] [EC:7.5.2.-]
BCAN_A0241 lacK; Lactose transport ATP-binding protein lacK [KO:K10112 ] [EC:7.5.2.-]
BCAN_B0753 lacK; Lactose transport ATP-binding protein lacK [KO:K10112 ] [EC:7.5.2.-]
BCAN_B0517 binding-protein-dependent transport systems inner membrane component [KO:K10118 ]
BCAN_B0306 binding-protein-dependent transport systems inner membrane component [KO:K10237 ]
BCAN_B0957 chvE; Multiple sugar-binding periplasmic receptor chvE precursor [KO:K10546 ]
BCAN_B0956 araG; L-arabinose transport ATP-binding protein araG [KO:K10548 ] [EC:7.5.2.-]
BCAN_B0690 amyD; Probable starch degradation products transport system permease protein amyD [KO:K17316 ]
BCAN_B1179 xylF; D-xylose ABC transporter, substrate-binding protein [KO:K10543 ]
BCAN_B0266 chvE; Multiple sugar-binding periplasmic receptor chvE precursor [KO:K10543 ]
BCAN_A1669 ribose/galactose/methyl galactoside import ATP-binding protein 2 [KO:K17207 ]
BCAN_B0969 yhdW; amino-acid ABC transporter-binding protein yhdW precursor [KO:K09969 ]
BCAN_A0758 amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family [KO:K09970 ]
BCAN_A0759 amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family [KO:K09971 ]
BCAN_A0760 bztD; Glutamate/glutamine/aspartate/asparagine transport ATP-binding protein bztD [KO:K09972 ] [EC:7.4.2.1 ]
BCAN_A2004 bztD; Glutamate/glutamine/aspartate/asparagine transport ATP-binding protein bztD [KO:K09972 ] [EC:7.4.2.1 ]
BCAN_B0681 amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family [KO:K10009 ]
BCAN_B0396 branched-chain amino acid ABC transporter, permease protein [KO:K01997 ]
BCAN_B1224 high-affinity branched-chain amino acid transporter membrane protein [KO:K01997 ]
BCAN_B0398 ATP/GTP-binding site motif A (P-loop):ABC transporter:AAA ATPase [KO:K01996 ]
BCAN_B1207 branched-chain amino acid transport ATP-binding protein livF [KO:K01996 ]
BCAN_B1227 high-affinity branched-chain amino acid transporter ATP-binding protein [KO:K01996 ]
BCAN_B0983 metI; D-methionine transport system permease protein metI [KO:K02072 ]
BCAN_B0535 binding-protein-dependent transport systems inner membrane component [KO:K15582 ]
BCAN_B0818 nikA; nickel ABC transporter, periplasmic nickel-binding protein [KO:K15584 ]
BCAN_A0007 binding-protein-dependent transport systems inner membrane component [KO:K13895 ]
BCAN_A0838 lipoprotein releasing system, transmembrane protein, LolC/E family [KO:K09808 ]
BCAN_A0839 lolD; Lipoprotein-releasing system ATP-binding protein lolD [KO:K09810 ] [EC:7.6.2.-]
BCAN_B0508 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC [KO:K16012 ]
BCAN_B0507 cydD; ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD [KO:K16013 ]
BCAN_A1711 macB; Macrolide export ATP-binding/permease protein macB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
LinkDB
All DBs