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Entry
Name
ABC transporters - Brucella abortus bv. 1 9-941
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Brucella abortus bv. 1 9-941 [GN:
bmb ]
Gene
BruAb1_1330 hypothetical sulfate ABC transporter, sulfate-binding protein [KO:K02048 ]
BruAb2_0088 modA; ModeA, molybdenum ABC transporter, periplasmic molybdenum-binding protein [KO:K02020 ]
BruAb2_0530 iron compound ABC transporter, periplasmic iron compound-binding protein, hypothetical [KO:K02012 ]
BruAb2_0531 iron compound ABC transporter, permease protein, hypothetical [KO:K02011 ]
BruAb1_1599 hypothetical spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein [KO:K11073 ]
BruAb2_0494 glycine betaine/L-proline ABC transporter, periplasmic glycine betaine-binding protein, hypothetical [KO:K02002 ]
BruAb1_1566 hypothetical glycine betaine/L-proline ABC transporter, periplasmic glycine betaine-binding protein [KO:K02002 ]
BruAb2_0493 glycine betaine/L-proline ABC transporter, permease protein, hypothetical [KO:K02001 ]
BruAb1_1567 hypothetical glycine betaine/L-proline ABC transporter, permease protein [KO:K02001 ]
BruAb1_0220 ABC transporter, periplasmic substrate-binding protein, hypothetical [KO:K05845 ]
BruAb2_0540 hypothetical ATP-binding ABC transporter protein [KO:K10112 ] [EC:7.5.2.-]
BruAb2_1119 hypothetical sugar ABC transporter, ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
BruAb2_0487 sugar ABC transporter, ATP-binding protein, hypothetical [KO:K10112 ] [EC:7.5.2.-]
BruAb2_1087 xylF; XylF, D-xylose ABC transporter, periplasmic D-xylose-binding protein [KO:K10543 ]
BruAb2_0915 hypothetical sugar ABC transporter periplasmic sugar-binding protein [KO:K10543 ]
BruAb2_0373 rbsB-2; RbsB-2, ribose ABC transporter, periplasmic D-ribose-binding protein [KO:K17202 ]
BruAb2_0571 ugpB; UgbB, glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein [KO:K05813 ]
BruAb2_0570 ugpA; UgpA, glycerol-3-phosphate ABC transporter, permease protein [KO:K05814 ]
BruAb2_0569 ugpE; UgpE, glycerol-3-phosphate ABC transporter, permease protein [KO:K05815 ]
BruAb2_0285 amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K09969 ]
BruAb2_0547 fliY; FliY, amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K02424 ]
BruAb1_1294 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, hypothetical [KO:K01999 ]
BruAb2_1129 hypothetical branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
BruAb2_1109 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, hypothetical [KO:K01999 ]
BruAb2_0801 hypothetical branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
BruAb2_0809 hypothetical branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
BruAb1_1765 hypothetical branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
BruAb1_1767 hypothetical branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
BruAb2_0578 amino acid ABC transporter, periplasmic amino-acid binding protein [KO:K01999 ]
BruAb2_0024 hypothetical branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
BruAb2_0280 hypothetical branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
BruAb2_1132 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
BruAb2_0575 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
BruAb2_0027 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
BruAb2_0279 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
BruAb2_1133 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
BruAb2_1112 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
BruAb2_0806 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
BruAb1_1769 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
BruAb2_0574 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
BruAb2_0028 branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
BruAb2_0278 hypothetical LivF, branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
BruAb2_0685 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein [KO:K15580 ]
BruAb2_0684 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein [KO:K15580 ]
BruAb1_0009 ABC transporter, periplasmic substrate-binding protein, hypothetical [KO:K13893 ]
BruAb1_0010 ABC transporter, periplasmic substrate-binding protein, hypothetical [KO:K13893 ]
BruAb2_1059 znuA; ZnuA, zinc ABC transporter, periplasmic zinc-bnding protein [KO:K09815 ]
BruAb1_0838 lolD; LolD, lipoprotein releasing system ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
BruAb1_1972 ftsE; FtsE, cell division ABC transporter, ATP-binding protein [KO:K09812 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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