KEGG   PATHWAY: bra00360
Entry
bra00360                    Pathway                                
Name
Phenylalanine metabolism - Bradyrhizobium sp. ORS 278
Class
Metabolism; Amino acid metabolism
Pathway map
bra00360  Phenylalanine metabolism
bra00360

Other DBs
GO: 0006558
Organism
Bradyrhizobium sp. ORS 278 [GN:bra]
Gene
BRADO5059  putative pyridoxal-dependent decarboxylase [KO:K01593] [EC:4.1.1.28 4.1.1.105]
BRADO6525  Histamine oxidase (EC 1.4.3.6) (Copper amine oxidase) [KO:K00276] [EC:1.4.3.21]
BRADO0266  conserved hypothetical protein; putative amine oxidase [KO:K00274] [EC:1.4.3.4]
BRADO1842  putative amine oxidase [KO:K00274] [EC:1.4.3.4]
BRADO2524  paaK; phenylacetyl-CoA ligase [KO:K01912] [EC:6.2.1.30]
BRADO2525  paaI; phenylacetic acid degradation protein with thioesterase/thiol ester dehydrase-isomerase domain [KO:K02614] [EC:3.1.2.-]
BRADO2519  paaA; Phenylacetic acid degradation protein paaA [KO:K02609] [EC:1.14.13.149]
BRADO2520  paaB; Phenylacetic acid degradation protein paaB [KO:K02610]
BRADO2521  paaC; Phenylacetic acid degradation protein paaC [KO:K02611] [EC:1.14.13.149]
BRADO2522  paaD; Phenylacetic acid degradation protein paaD [KO:K02612]
BRADO2523  putative phenylacetic acid degradation NADH oxidoreductase paaE. [KO:K02613]
BRADO2571  putative enoyl-CoA hydratase [KO:K15866] [EC:5.3.3.18]
BRADO0646  putative enoyl-CoA hydratase [KO:K15866] [EC:5.3.3.18]
BRADO2663  Putative enoyl-CoA hydratase [KO:K01692] [EC:4.2.1.17]
BRADO3444  hbdA; 3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD) [KO:K00074] [EC:1.1.1.157]
BRADO2315  putative 3-hydroxyacyl-CoA dehydrogenase [KO:K00074] [EC:1.1.1.157]
BRADO6490  hbdA; 3-hydroxybutyryl-CoA dehydrogenase (Beta-hydroxybutyryl-CoA dehydrogenase) (BHBD) [KO:K00074] [EC:1.1.1.157]
BRADO5973  aatA; aspartate aminotransferase A (AspAT) [KO:K00812] [EC:2.6.1.1]
BRADO6463  hisC; histidinol-phosphate aminotransferase [KO:K00817] [EC:2.6.1.9]
BRADO4744  putative histidinol-phosphate aminotransferase (HisC-like) [KO:K00817] [EC:2.6.1.9]
BRADO0818  hisC; Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase) [KO:K00817] [EC:2.6.1.9]
BRADO3492  aminotransferase (class-I pyridoxal-phosphate-dependent and class II); possible aspartate aminotransferase, tyrosine aminotransferase or aromatic amino acid aminotransferase [KO:K00832] [EC:2.6.1.57]
BRADO6961  hpd; 4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]
BRADO6144  Putative D-alanine aminotransferase [KO:K00824] [EC:2.6.1.21]
BRADO2597  Putative hypothetical oxidoreductase [KO:K13574] [EC:1.1.1.237 1.1.1.-]
BRADO1666  katG; catalase; hydroperoxidase HPI(I) [KO:K03782] [EC:1.11.1.21]
BRADO5789  putative amidase [KO:K01426] [EC:3.5.1.4]
BRADO5869  amiE; Aliphatic amidase (amiE) [KO:K01426] [EC:3.5.1.4]
BRADO4071  amidase [KO:K01426] [EC:3.5.1.4]
BRADO4399  putative amidase [KO:K01426] [EC:3.5.1.4]
BRADO4407  putative amidase [KO:K01426] [EC:3.5.1.4]
BRADO1531  amdA; amidase [KO:K01426] [EC:3.5.1.4]
BRADO0922  putative amidase [KO:K01426] [EC:3.5.1.4]
BRADO2532  putative amidotransferase [KO:K01426] [EC:3.5.1.4]
BRADO1769  bam; Indoleacetamide hydrolase (IAH) (Indole-3-acetamide hydrolase) [KO:K01426] [EC:3.5.1.4]
BRADO2088  bam; Indoleacetamide hydrolase (IAH) (Indole-3-acetamide hydrolase) [KO:K01426] [EC:3.5.1.4]
BRADO5611  putative amidase [KO:K01426] [EC:3.5.1.4]
BRADO0898  putative amidase [KO:K01426] [EC:3.5.1.4]
BRADO2491  putative ferredoxin--NAD(+) reductase [KO:K00529] [EC:1.18.1.3]
BRADO5116  putative FAD-binding monooxygenase; putative 3-(3-hydroxy-phenyl)propionate hydroxylase [KO:K05712] [EC:1.14.13.127]
BRADO6045  putative FAD-binding monooxygenase; putative 3-(3-hydroxy-phenyl)propionate hydroxylase [KO:K05712] [EC:1.14.13.127]
BRADO6299  putative FAD-binding monooxygenase [KO:K05712] [EC:1.14.13.127]
BRADO6969  putative FAD-binding Monooxygenase [KO:K05712] [EC:1.14.13.127]
BRADO0185  putative Hydratase/decarboxylase [KO:K02554] [EC:4.2.1.80]
BRADO5041  putative hydratase/decarboxylase; putative 4-oxalocrotonate decarboxylase [KO:K02554] [EC:4.2.1.80]
Compound
C00022  Pyruvate
C00024  Acetyl-CoA
C00042  Succinate
C00079  L-Phenylalanine
C00082  L-Tyrosine
C00084  Acetaldehyde
C00091  Succinyl-CoA
C00122  Fumarate
C00166  Phenylpyruvate
C00423  trans-Cinnamate
C00512  Benzoyl-CoA
C00582  Phenylacetyl-CoA
C00596  2-Hydroxy-2,4-pentadienoate
C00601  Phenylacetaldehyde
C00642  4-Hydroxyphenylacetate
C01198  3-(2-Hydroxyphenyl)propanoate
C01772  trans-2-Hydroxycinnamate
C02137  alpha-Oxo-benzeneacetic acid
C02232  3-Oxoadipyl-CoA
C02265  D-Phenylalanine
C02505  2-Phenylacetamide
C02763  2-Hydroxy-3-phenylpropenoate
C03519  N-Acetyl-L-phenylalanine
C03589  4-Hydroxy-2-oxopentanoate
C04044  3-(2,3-Dihydroxyphenyl)propanoate
C04148  Phenylacetylglutamine
C04479  2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate
C05332  Phenethylamine
C05593  3-Hydroxyphenylacetate
C05598  Phenylacetylglycine
C05607  Phenyllactate
C05629  Phenylpropanoate
C05852  2-Hydroxyphenylacetate
C05853  Phenylethyl alcohol
C06207  2,6-Dihydroxyphenylacetate
C07086  Phenylacetic acid
C11457  3-(3-Hydroxyphenyl)propanoic acid
C11588  cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol
C12621  trans-3-Hydroxycinnamate
C12622  cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol
C12623  trans-2,3-Dihydroxycinnamate
C12624  2-Hydroxy-6-ketononatrienedioate
C14144  5-Carboxy-2-pentenoyl-CoA
C14145  (3S)-3-Hydroxyadipyl-CoA
C15524  Phenylglyoxylyl-CoA
C19945  3-Oxo-5,6-dehydrosuberyl-CoA
C19946  3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde
C19975  2-Oxepin-2(3H)-ylideneacetyl-CoA
C20062  2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA
Reference
  Authors
Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  Title
[Cellular Functions and Metabolic Maps] (In Japanese)
  Journal
Tokyo Kagaku Dojin (1997)
Reference
PMID:10537203
  Authors
Arai H, Yamamoto T, Ohishi T, Shimizu T, Nakata T, Kudo T.
  Title
Genetic organization and characteristics of the 3-(3-hydroxyphenyl)propionic acid degradation pathway of Comamonas testosteroni TA441.
  Journal
Microbiology 145 ( Pt 10):2813-20 (1999)
DOI:10.1099/00221287-145-10-2813
Reference
PMID:9603882
  Authors
Diaz E, Ferrandez A, Garcia JL.
  Title
Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.
  Journal
J Bacteriol 180:2915-23 (1998)
DOI:10.1128/JB.180.11.2915-2923.1998
Reference
PMID:9098055
  Authors
Ferrandez A, Garcia JL, Diaz E.
  Title
Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.
  Journal
J Bacteriol 179:2573-81 (1997)
DOI:10.1128/JB.179.8.2573-2581.1997
Reference
PMID:19016485
  Authors
Hwang JY, Park J, Seo JH, Cha M, Cho BK, Kim J, Kim BG
  Title
Simultaneous synthesis of 2-phenylethanol and L-homophenylalanine using aromatic transaminase with yeast Ehrlich pathway.
  Journal
Biotechnol Bioeng 102:1323-9 (2009)
DOI:10.1002/bit.22178
Reference
PMID:20660314
  Authors
Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G
  Title
Bacterial phenylalanine and phenylacetate catabolic pathway revealed.
  Journal
Proc Natl Acad Sci U S A 107:14390-5 (2010)
DOI:10.1073/pnas.1005399107
Related
pathway
bra00010  Glycolysis / Gluconeogenesis
bra00020  Citrate cycle (TCA cycle)
bra00350  Tyrosine metabolism
bra00362  Benzoate degradation
bra00400  Phenylalanine, tyrosine and tryptophan biosynthesis
bra00643  Styrene degradation
KO pathway
ko00360   
LinkDB

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