KEGG PATHWAY: bthe00360

KEGG

PATHWAY: bthe00360

Entry

bthe00360                   Pathway

Name

Phenylalanine metabolism - Burkholderia thailandensis E254

Class

Metabolism; Amino acid metabolism

Pathway map

Phenylalanine metabolism

Other DBs

GO:

Organism

Burkholderia thailandensis E254 [GN:bthe]

Gene

phhA; phenylalanine-4-hydroxylase [KO:K00500] [EC:1.14.16.1]

aldehyde dehydrogenase family protein [KO:K00146] [EC:1.2.1.39]

aldehyde dehydrogenase family protein [KO:K00146] [EC:1.2.1.39]

aldehyde dehydrogenase family protein [KO:K00146] [EC:1.2.1.39]

paaF; phenylacetate-CoA ligase [KO:K01912] [EC:6.2.1.30]

paaF; phenylacetate-CoA ligase [KO:K01912] [EC:6.2.1.30]

paaD; phenylacetic acid degradation protein PaaD [KO:K02614] [EC:3.1.2.-]

phenylacetic acid catabolic family protein [KO:K02609] [EC:1.14.13.149]

phenylacetic acid degradation B [KO:K02610]

phenylacetic acid catabolic family protein [KO:K02611] [EC:1.14.13.149]

paaJ; phenylacetate-CoA oxygenase, PaaJ subunit [KO:K02612]

2Fe-2S iron-sulfur cluster binding domain protein [KO:K02613]

paaB; phenylacetate degradation putative enoyl-CoA hydratase PaaB [KO:K15866] [EC:5.3.3.18]

enoyl-CoA hydratase/isomerase family protein [KO:K01692] [EC:4.2.1.17]

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein [KO:K00074] [EC:1.1.1.157]

hisC; histidinol-phosphate transaminase [KO:K00817] [EC:2.6.1.9]

hisC; histidinol-phosphate transaminase [KO:K00817] [EC:2.6.1.9]

tyrB; tyrosine aminotransferase [KO:K00832] [EC:2.6.1.57]

aminotransferase class I and II family protein [KO:K00832] [EC:2.6.1.57]

tyrB; tyrosine aminotransferase [KO:K00832] [EC:2.6.1.57]

hppD; 4-hydroxyphenylpyruvate dioxygenase [KO:K00457] [EC:1.13.11.27]

glyoxalase/Bleomycin resistance/Dioxygenase superfamily protein [KO:K00457] [EC:1.13.11.27]

ketopantoate reductase PanE/ApbA family protein [KO:K00285] [EC:1.4.5.1]

ketopantoate reductase PanE/ApbA family protein [KO:K00285] [EC:1.4.5.1]

aminotransferase class IV family protein [KO:K00824] [EC:2.6.1.21]

katG; catalase/peroxidase HPI [KO:K03782] [EC:1.11.1.21]

amidase family protein [KO:K01426] [EC:3.5.1.4]

amidase family protein [KO:K01426] [EC:3.5.1.4]

amidase family protein [KO:K01426] [EC:3.5.1.4]

amidase family protein [KO:K01426] [EC:3.5.1.4]

amidase family protein [KO:K01426] [EC:3.5.1.4]

amidase family protein [KO:K01426] [EC:3.5.1.4]

amidase family protein [KO:K01426] [EC:3.5.1.4]

rieske [2Fe-2S] domain protein [KO:K05710]

pyridine nucleotide-disulfide oxidoreductase family protein [KO:K00529] [EC:1.18.1.3]

FAD binding domain protein [KO:K05712] [EC:1.14.13.127]

dmpG; 4-hydroxy-2-oxovalerate aldolase [KO:K01666] [EC:4.1.3.39]

acetaldehyde dehydrogenase [KO:K04073] [EC:1.2.1.10]

Compound

Pyruvate

Acetyl-CoA

Succinate

L-Phenylalanine

L-Tyrosine

Acetaldehyde

Succinyl-CoA

Fumarate

Phenylpyruvate

trans-Cinnamate

Benzoyl-CoA

Phenylacetyl-CoA

2-Hydroxy-2,4-pentadienoate

Phenylacetaldehyde

4-Hydroxyphenylacetate

3-(2-Hydroxyphenyl)propanoate

trans-2-Hydroxycinnamate

alpha-Oxo-benzeneacetic acid

3-Oxoadipyl-CoA

D-Phenylalanine

2-Phenylacetamide

2-Hydroxy-3-phenylpropenoate

N-Acetyl-L-phenylalanine

4-Hydroxy-2-oxopentanoate

3-(2,3-Dihydroxyphenyl)propanoate

Phenylacetylglutamine

2-Hydroxy-6-oxonona-2,4-diene-1,9-dioate

Phenethylamine

3-Hydroxyphenylacetate

Phenylacetylglycine

Phenyllactate

Phenylpropanoate

2-Hydroxyphenylacetate

Phenylethyl alcohol

2,6-Dihydroxyphenylacetate

Phenylacetic acid

3-(3-Hydroxyphenyl)propanoic acid

cis-3-(Carboxy-ethyl)-3,5-cyclo-hexadiene-1,2-diol

trans-3-Hydroxycinnamate

cis-3-(3-Carboxyethenyl)-3,5-cyclohexadiene-1,2-diol

trans-2,3-Dihydroxycinnamate

2-Hydroxy-6-ketononatrienedioate

5-Carboxy-2-pentenoyl-CoA

(3S)-3-Hydroxyadipyl-CoA

Phenylglyoxylyl-CoA

3-Oxo-5,6-dehydrosuberyl-CoA

3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde

2-Oxepin-2(3H)-ylideneacetyl-CoA

2-(1,2-Epoxy-1,2-dihydrophenyl)acetyl-CoA

Reference

Authors

Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).

Title

[Cellular Functions and Metabolic Maps] (In Japanese)

Journal

Tokyo Kagaku Dojin (1997)

Reference

Authors

Arai H, Yamamoto T, Ohishi T, Shimizu T, Nakata T, Kudo T.

Title

Genetic organization and characteristics of the 3-(3-hydroxyphenyl)propionic acid degradation pathway of Comamonas testosteroni TA441.

Journal

Microbiology 145 ( Pt 10):2813-20 (1999)
DOI:10.1099/00221287-145-10-2813

Reference

Authors

Diaz E, Ferrandez A, Garcia JL.

Title

Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12.

Journal

J Bacteriol 180:2915-23 (1998)
DOI:10.1128/JB.180.11.2915-2923.1998

Reference

Authors

Ferrandez A, Garcia JL, Diaz E.

Title

Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12.

Journal

J Bacteriol 179:2573-81 (1997)
DOI:10.1128/JB.179.8.2573-2581.1997

Reference

Authors

Hwang JY, Park J, Seo JH, Cha M, Cho BK, Kim J, Kim BG

Title

Simultaneous synthesis of 2-phenylethanol and L-homophenylalanine using aromatic transaminase with yeast Ehrlich pathway.

Journal

Biotechnol Bioeng 102:1323-9 (2009)
DOI:10.1002/bit.22178

Reference

Authors

Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G

Title

Bacterial phenylalanine and phenylacetate catabolic pathway revealed.

Journal

Proc Natl Acad Sci U S A 107:14390-5 (2010)
DOI:10.1073/pnas.1005399107

Related
pathway

Glycolysis / Gluconeogenesis

Citrate cycle (TCA cycle)

Tyrosine metabolism

Benzoate degradation

Phenylalanine, tyrosine and tryptophan biosynthesis

Styrene degradation

KO pathway

LinkDB

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