PATHWAY: bxb02010 Help
Entry
Name
ABC transporters - Paraburkholderia xenovorans LB400
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Paraburkholderia xenovorans LB400 [GN:
bxb ]
Gene
DR64_1943 sulfate ABC transporter, sulfate-binding family protein [KO:K02048 ]
DR64_161 sulfate ABC transporter, sulfate-binding family protein [KO:K23163 ]
DR64_160 cysT; sulfate ABC transporter, permease protein CysT [KO:K02046 ]
DR64_159 cysW; sulfate ABC transporter, permease protein CysW [KO:K02047 ]
DR64_1886 tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
DR64_6025 tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
DR64_8340 tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
DR64_1884 binding--dependent transport system inner membrane component family protein [KO:K15552 ]
DR64_6023 binding--dependent transport system inner membrane component family protein [KO:K15552 ]
DR64_8342 binding--dependent transport system inner membrane component family protein [KO:K15552 ]
DR64_4969 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
DR64_5360 ABC transporter, substrate-binding , aliphatic sulfonates family protein [KO:K15553 ]
DR64_4314 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
DR64_8197 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
DR64_8270 ABC transporter, substrate-binding , aliphatic sulfonates family protein [KO:K15553 ]
DR64_8293 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
DR64_8322 ABC transporter, substrate-binding , aliphatic sulfonates family protein [KO:K15553 ]
DR64_7468 ABC transporter, substrate-binding , aliphatic sulfonates family protein [KO:K15553 ]
DR64_5829 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
DR64_61 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
DR64_849 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
DR64_4326 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_4317 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_185 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_4737 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_4312 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_4313 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_4971 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_8194 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_8195 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_8294 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_8295 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_7470 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_8273 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_59 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_8312 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_5827 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR64_6787 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
DR64_5177 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
DR64_6506 bacterial extracellular solute-binding family protein [KO:K02020 ]
DR64_6364 bacterial extracellular solute-binding family protein [KO:K02012 ]
DR64_7064 bacterial extracellular solute-binding family protein [KO:K02012 ]
DR64_7142 bacterial extracellular solute-binding family protein [KO:K02012 ]
DR64_6363 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
DR64_7143 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
DR64_6261 bacterial extracellular solute-binding family protein [KO:K11073 ]
DR64_4109 bacterial extracellular solute-binding family protein [KO:K11073 ]
DR64_6258 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
DR64_4112 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
DR64_6259 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
DR64_4111 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
DR64_7185 phnS; 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein [KO:K11081 ]
DR64_7182 phnV; 2-aminoethylphosphonate ABC transport system, membrane component PhnV [KO:K11082 ]
DR64_7183 phnU; 2-aminoethylphosphonate ABC transporter, permease protein [KO:K11083 ]
DR64_7184 phnT; 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT [KO:K11084 ]
DR64_6151 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
DR64_6875 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
DR64_6879 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
DR64_6915 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
DR64_373 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
DR64_5324 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845 ]
DR64_5323 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
DR64_5325 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
DR64_2888 bacterial extracellular solute-binding family protein [KO:K10227 ]
DR64_2889 binding--dependent transport system inner membrane component family protein [KO:K10228 ]
DR64_2890 binding--dependent transport system inner membrane component family protein [KO:K10229 ]
DR64_6675 branched-chain amino acid transport system / permease component family protein [KO:K23535 ]
DR64_4098 branched-chain amino acid transport system / permease component family protein [KO:K23535 ]
DR64_4099 branched-chain amino acid transport system / permease component family protein [KO:K23536 ]
DR64_6676 branched-chain amino acid transport system / permease component family protein [KO:K23536 ]
DR64_7384 bacterial extracellular solute-binding family protein [KO:K17315 ]
DR64_1151 binding--dependent transport system inner membrane component family protein [KO:K17316 ]
DR64_7383 binding--dependent transport system inner membrane component family protein [KO:K17316 ]
DR64_1150 binding--dependent transport system inner membrane component family protein [KO:K17317 ]
DR64_7382 binding--dependent transport system inner membrane component family protein [KO:K17317 ]
DR64_5295 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR64_4156 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR64_5888 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR64_5903 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR64_8461 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR64_1365 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR64_4158 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR64_5905 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR64_5921 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR64_5922 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR64_8460 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR64_6702 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR64_2721 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10537 ]
DR64_2723 branched-chain amino acid transport system / permease component family protein [KO:K10538 ]
DR64_2015 periplasmic binding s and sugar binding domain of LacI family protein [KO:K23508 ]
DR64_2018 branched-chain amino acid transport system / permease component family protein [KO:K23509 ]
DR64_2017 branched-chain amino acid transport system / permease component family protein [KO:K23509 ]
DR64_4954 xylF; D-xylose ABC transporter, D-xylose-binding protein [KO:K10543 ]
DR64_4952 branched-chain amino acid transport system / permease component family protein [KO:K10544 ]
DR64_6215 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10552 ]
DR64_6214 branched-chain amino acid transport system / permease component family protein [KO:K10553 ]
DR64_6359 rhaS; rhamnose ABC transporter, rhamnose-binding protein [KO:K10559 ]
DR64_6357 branched-chain amino acid transport system / permease component family protein [KO:K10560 ]
DR64_6358 branched-chain amino acid transport system / permease component family protein [KO:K10561 ]
DR64_2619 bacterial extracellular solute-binding family protein [KO:K05813 ]
DR64_2618 binding--dependent transport system inner membrane component family protein [KO:K05814 ]
DR64_2617 binding--dependent transport system inner membrane component family protein [KO:K05815 ]
DR64_3424 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
DR64_5095 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
DR64_5099 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
DR64_3425 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
DR64_3426 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
DR64_6160 phnD; phosphonate ABC transporter, periplasmic phosphonate binding protein [KO:K02044 ]
DR64_6159 phnE; phosphonate ABC transporter, permease protein PhnE [KO:K02042 ]
DR64_4519 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
DR64_2109 bacterial extracellular solute-binding s, 3 family protein [KO:K10013 ]
DR64_599 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
DR64_5552 bacterial extracellular solute-binding s, 3 family protein [KO:K10013 ]
DR64_1092 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
DR64_608 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
DR64_1091 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
DR64_609 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
DR64_2767 bacterial extracellular solute-binding s, 3 family protein [KO:K10001 ]
DR64_2769 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10002 ]
DR64_2768 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10003 ]
DR64_7135 bacterial extracellular solute-binding s, 3 family protein [KO:K10018 ]
DR64_7133 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10019 ]
DR64_7134 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10020 ]
DR64_202 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
DR64_3597 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
DR64_8517 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
DR64_203 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
DR64_3598 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
DR64_2199 branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein [KO:K01999 ]
DR64_7932 branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein [KO:K01999 ]
DR64_7501 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
DR64_6319 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_4892 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_3479 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_2200 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_2204 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_2987 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_5989 branched-chain amino acid transport system / permease component family protein [KO:K01997 K01998 ]
DR64_436 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_1399 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_8211 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_7947 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_7455 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_7884 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_8331 branched-chain amino acid transport system / permease component family protein [KO:K01997 K01998 ]
DR64_7584 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_7514 branched-chain amino acid transport system / permease component family protein [KO:K01997 K01998 ]
DR64_5136 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR64_2205 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DR64_1400 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DR64_7454 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DR64_5135 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_6320 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_4891 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_437 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_2201 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_2988 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_7946 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_8210 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_7583 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_7883 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_3480 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR64_7581 livF; high-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
DR64_6176 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
DR64_3157 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
DR64_8557 branched-chain amino acid transport system / permease component family protein [KO:K11960 ]
DR64_8505 branched-chain amino acid transport system / permease component family protein [KO:K11960 ]
DR64_8011 branched-chain amino acid transport system / permease component family protein [KO:K11961 ]
DR64_8559 branched-chain amino acid transport system / permease component family protein [KO:K11961 ]
DR64_8506 branched-chain amino acid transport system / permease component family protein [KO:K11961 K11962 ]
DR64_6086 oppB; oligopeptide transport system permease protein oppB [KO:K15581 ]
DR64_6085 binding--dependent transport system inner membrane component family protein [KO:K15582 ]
DR64_1927 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
DR64_2354 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
DR64_2355 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
DR64_2356 binding--dependent transport system inner membrane component family protein [KO:K12369 ]
DR64_2357 binding--dependent transport system inner membrane component family protein [KO:K12370 ]
DR64_3000 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13889 ]
DR64_3001 binding--dependent transport system inner membrane component family protein [KO:K13890 ]
DR64_3002 gsiD; glutathione transport system permease protein gsiD [KO:K13891 ]
DR64_3796 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
DR64_671 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
DR64_3797 binding--dependent transport system inner membrane component family protein [KO:K13894 ]
DR64_670 binding--dependent transport system inner membrane component family protein [KO:K13894 ]
DR64_3798 binding--dependent transport system inner membrane component family protein [KO:K13895 ]
DR64_669 binding--dependent transport system inner membrane component family protein [KO:K13895 ]
DR64_3727 liporeleasing system, transmembrane , LolC/E family protein [KO:K09808 ]
DR64_3728 lolD; liporeleasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
LinkDB
All DBs