Entry
Name
ABC transporters - Cellulomonas flavigena
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Cellulomonas flavigena [GN:
cfl ]
Gene
Cfla_1383 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein [KO:K15553 ]
Cfla_1382 binding-protein-dependent transport systems inner membrane component [KO:K15554 ]
Cfla_1751 molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
Cfla_0218 ABC transporter, periplasmic binding protein, thiB subfamily [KO:K02064 ]
Cfla_0219 binding-protein-dependent transport systems inner membrane component [KO:K02063 ]
Cfla_1499 binding-protein-dependent transport systems inner membrane component [KO:K11070 ]
Cfla_1498 binding-protein-dependent transport systems inner membrane component [KO:K11071 ]
Cfla_1338 Substrate-binding region of ABC-type glycine betaine transport system [KO:K05845 ]
Cfla_1339 binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
Cfla_1340 binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
Cfla_2173 binding-protein-dependent transport systems inner membrane component [KO:K15771 ]
Cfla_2172 binding-protein-dependent transport systems inner membrane component [KO:K15772 ]
Cfla_1127 binding-protein-dependent transport systems inner membrane component [KO:K10118 ]
Cfla_3364 binding-protein-dependent transport systems inner membrane component [KO:K10118 ]
Cfla_3051 binding-protein-dependent transport systems inner membrane component [KO:K10118 ]
Cfla_1128 binding-protein-dependent transport systems inner membrane component [KO:K10119 ]
Cfla_3050 binding-protein-dependent transport systems inner membrane component [KO:K10119 ]
Cfla_3363 binding-protein-dependent transport systems inner membrane component [KO:K10119 ]
Cfla_3181 binding-protein-dependent transport systems inner membrane component [KO:K10233 ]
Cfla_3180 binding-protein-dependent transport systems inner membrane component [KO:K10234 ]
Cfla_2805 binding-protein-dependent transport systems inner membrane component [KO:K17319 ]
Cfla_3000 binding-protein-dependent transport systems inner membrane component [KO:K17319 ]
Cfla_2804 binding-protein-dependent transport systems inner membrane component [KO:K17320 ]
Cfla_2999 binding-protein-dependent transport systems inner membrane component [KO:K17320 ]
Cfla_0961 binding-protein-dependent transport systems inner membrane component [KO:K10237 ]
Cfla_0962 binding-protein-dependent transport systems inner membrane component [KO:K10238 ]
Cfla_2400 binding-protein-dependent transport systems inner membrane component [KO:K10241 ]
Cfla_2401 binding-protein-dependent transport systems inner membrane component [KO:K10242 ]
Cfla_2520 putative sugar ABC transporter, substrate-binding protein [KO:K10546 ]
Cfla_3404 putative sugar uptake ABC transporter periplasmic solute-binding protein precursor [KO:K10546 ]
Cfla_3041 periplasmic binding protein/LacI transcriptional regulator [KO:K23508 ]
Cfla_0658 phosphate ABC transporter, periplasmic phosphate-binding protein [KO:K02040 ]
Cfla_0659 phosphate ABC transporter, inner membrane subunit PstC [KO:K02037 ]
Cfla_0660 phosphate ABC transporter, inner membrane subunit PstA [KO:K02038 ]
Cfla_1549 polar amino acid ABC transporter, inner membrane subunit [KO:K10006 ]
Cfla_1548 polar amino acid ABC transporter, inner membrane subunit [KO:K10007 ]
Cfla_3161 binding-protein-dependent transport systems inner membrane component [KO:K02072 ]
Cfla_0982 binding-protein-dependent transport systems inner membrane component [KO:K13890 ]
Cfla_0983 binding-protein-dependent transport systems inner membrane component [KO:K13891 ]
Cfla_2288 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC [KO:K16012 ]
Cfla_2287 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD [KO:K16013 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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