KEGG   PATHWAY: ege00740
Entry
ege00740                    Pathway                                
Name
Riboflavin metabolism - Duffyella gerundensis
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
ege00740  Riboflavin metabolism
ege00740

Module
ege_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:ege00740]
Other DBs
GO: 0006771
Organism
Duffyella gerundensis [GN:ege]
Gene
EM595_1947  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
EM595_0952  ribD; bifunctional pyrimidine deaminase/reductase in pathway of riboflavin synthesis [KO:K11752] [EC:3.5.4.26 1.1.1.193]
EM595_1046  ybjI; Flavin mononucleotide phosphatase YbjI [KO:K20861] [EC:3.1.3.102 3.1.3.104]
EM595_3315  yigB; Flavin mononucleotide phosphatase YigB [KO:K20862] [EC:3.1.3.102 3.1.3.104]
EM595_0533  ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase [KO:K02858] [EC:4.1.99.12]
EM595_0953  ribH; riboflavin synthase, beta chain [KO:K00794] [EC:2.5.1.78]
EM595_1691  ribE; riboflavin synthase, alpha chain [KO:K00793] [EC:2.5.1.9]
EM595_0680  ribF; putative regulator [KO:K11753] [EC:2.7.1.26 2.7.7.2]
EM595_0941  3-phytase [KO:K01093] [EC:3.1.3.26 3.1.3.2]
EM595_3285  ubiB1; FMN reductase [KO:K05368] [EC:1.5.1.41]
EM595_1316  ssuE; putative NAD(P)H-dependent FMN reductase [KO:K00299] [EC:1.5.1.38]
EM595_1786  nfrA2; FMN reductase [NAD(P)H] [KO:K19286] [EC:1.5.1.39]
EM595_2416  thiM; Hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
EM595_0540  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
EM595_1484  nudJ; Phosphatase NudJ [KO:K12152] [EC:3.6.1.-]
EM595_2525  ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
ege00030  Pentose phosphate pathway
ege00040  Pentose and glucuronate interconversions
ege00230  Purine metabolism
ege00860  Porphyrin metabolism
ege00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

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