Entry Name ABC transporters - Haemophilus influenzae 10810 (serotype b)
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Haemophilus influenzae 10810 (serotype b) [GN:
hiu ]
Gene HIB_04690 putative ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic component [KO:K15598 ]
HIB_04670 putative ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [KO:K15600 ]
HIB_11900 fused thiamin transporter subunits of ABC superfamily: membrane components [KO:K02063 ]
HIB_15120 spermidine/putrescine-binding periplasmic protein 1 precursor [KO:K11069 ]
HIB_12440 predicted toluene transporter subunit: membrane component of ABC superfamily [KO:K02066 ]
HIB_12450 predicted toluene transporter subunit: ATP-binding component of ABC superfamily [KO:K02065 ]
HIB_06280 fused D-ribose transporter subunits of ABC superfamily: ATP-binding components [KO:K10441 ] [EC:7.5.2.7 ]
HIB_09560 fused methyl-galactoside transporter subunits of ABC superfamily: ATP-binding components [KO:K10542 ] [EC:7.5.2.11 ]
HIB_12370 predicted transporter subunit: membrane component of ABC superfamily [KO:K10009 ]
HIB_01770 zinc transporter subunit: periplasmic-binding component of ABC superfamily [KO:K09815 ]
HIB_05180 zinc transporter subunit: membrane component of ABC superfamily [KO:K09816 ]
HIB_04720 putative ABC-type chelated iron transport system, permease component [KO:K11605 ]
HIB_04710 putative ABC-type chelated iron transport system, permease component [KO:K11606 ]
HIB_04730 putative ABC-type chelated iron transport system, ATPase component [KO:K11607 ]
HIB_18000 predicted ABC-type cobalt transport system, permease component [KO:K02007 ]
HIB_17980 predicted ABC-type cobalt transport system, ATPase component [KO:K02006 ]
HIB_18020 putative ABC-type Co2+ transport system, periplasmic component [KO:K10094 ]
HIB_17060 outer membrane-specific lipoprotein transporter subunit [KO:K09808 ]
HIB_17130 outer membrane-specific lipoprotein transporter subunit [KO:K09808 ]
HIB_17070 outer membrane-specific lipoprotein transporter subunit [KO:K09810 ] [EC:7.6.2.-]
HIB_09010 predicted transporter subunit: membrane component of ABC superfamily [KO:K09811 ]
HIB_09000 predicted transporter subunit: ATP-binding component of ABC superfamily [KO:K09812 ]
HIB_00530 fused lipid transporter subunits of ABC superfamily: membrane component/ATP-binding component [KO:K11085 ] [EC:7.5.2.6 ]
HIB_12120 conserved hypothetical abc transporter atp-binding protein [KO:K18893 ]
HIB_13140 fused cysteine transporter subunits of ABC superfamily: membrane component/ATP-binding component [KO:K16012 ]
HIB_13150 fused cysteine transporter subunits of ABC superfamily: membrane component/ATP-binding component [KO:K16013 ]
HIB_00360 fused predicted multidrug transporter subunits of ABC superfamily: membrane component/ATP-binding component [KO:K02471 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
