KEGG   PATHWAY: mgg02010
Entry
mgg02010                    Pathway                                
Name
ABC transporters - Micropruina glycogenica
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
mgg02010  ABC transporters
mgg02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Micropruina glycogenica [GN:mgg]
Gene
MPLG2_2080  Sulfate ABC transporter substrate-binding protein [KO:K23163]
MPLG2_2079  cysU; sulfate/thiosulfate transporter subunit; membrane component of ABC superfamily [KO:K02046]
MPLG2_2078  cysW; sulfate/thiosulfate transporter subunit; membrane component of ABC superfamily [KO:K02047]
MPLG2_2077  cysA; Sulfate/thiosulfate import ATP-binding protein CysA [KO:K02045] [EC:7.3.2.3]
MPLG2_2658  modA; Molybdate-binding protein [KO:K02020]
MPLG2_2657  modB; Molybdenum transport system permease protein ModB [KO:K02018]
MPLG2_2656  modC; Molybdenum import ATP-binding protein ModC [KO:K02017] [EC:7.3.2.5]
MPLG2_3462  ABC transporter periplasmic binding protein, thiB subfamily [KO:K02064]
MPLG2_3463  Binding-protein-dependent transport systems inner membrane component [KO:K02063]
MPLG2_3464  fbpC; Fe(3+) ions import ATP-binding protein FbpC [KO:K02062] [EC:7.6.2.15]
MPLG2_3280  Glycine/betaine ABC transporter [KO:K05845]
MPLG2_3281  Glycine betaine ABC transport system permease protein [KO:K05846]
MPLG2_3282  ABC transporter permease [KO:K05846]
MPLG2_3283  ABC transporter ATP-binding protein [KO:K05847] [EC:7.6.2.9]
MPLG2_3784  msmX; multiple sugar-binding transporter ATP-binding protein [KO:K10112] [EC:7.5.2.-]
MPLG2_2636  frlO; fructose amino acid-binding lipoprotein [KO:K10117]
MPLG2_2637  frlN; fructose-amino acid permease [KO:K10118]
MPLG2_2638  frlM; fructose-amino acid permease [KO:K10119]
MPLG2_0479  Multiple sugar transport system substrate-binding protein [KO:K10236]
MPLG2_0480  Carbohydrate ABC transporter membrane protein 1, CUT1 family [KO:K10237]
MPLG2_0481  sugB; Trehalose transport system permease protein SugB [KO:K10238]
MPLG2_0794  ABC transporter substrate-binding protein [KO:K17329]
MPLG2_0793  Sugar ABC transporter permease [KO:K17330]
MPLG2_0792  ABC transporter, permease protein [KO:K17331]
MPLG2_2239  Nucleoside-binding protein [KO:K07335]
MPLG2_2237  Nucleoside ABC transporter membrane protein [KO:K23535]
MPLG2_2236  Nucleoside ABC transporter membrane protein [KO:K23536]
MPLG2_2238  nupO; guanosine ABC transporter (ATP-binding protein) [KO:K23537]
MPLG2_0751  rbsB; ribose ABC transporter (ribose-binding lipoprotein) [KO:K10439]
MPLG2_3358  Sugar ABC transporter substrate-binding protein [KO:K10439]
MPLG2_0750  rbsC; ribose ABC transporter (permease) [KO:K10440]
MPLG2_3357  ABC transporter permease [KO:K10440]
MPLG2_3356  Sugar ABC transporter ATP-binding protein [KO:K10441] [EC:7.5.2.7]
MPLG2_0749  rbsA; ribose ABC transporter (ATP-binding protein) [KO:K10441] [EC:7.5.2.7]
MPLG2_0753  rbsD; D-ribose pyranase [KO:K06726] [EC:5.4.99.62]
MPLG2_3701  Phosphate-binding protein PstS [KO:K02040]
MPLG2_3700  pstC; Phosphate transport system permease protein PstC 2 [KO:K02037]
MPLG2_3699  pstA; Phosphate transport system permease protein PstA 1 [KO:K02038]
MPLG2_3698  pstBA; phosphate ABC transporter (ATP-binding protein) [KO:K02036] [EC:7.3.2.1]
MPLG2_2341  Glutamate transport system substrate-binding protein [KO:K10005]
MPLG2_3854  gluB; Glutamate-binding protein [KO:K10005]
MPLG2_3853  gluC; Glutamate transport system permease protein GluC [KO:K10006]
MPLG2_3852  putative glutamate transporter permease protein (GluD) [KO:K10007]
MPLG2_3855  glnQ; glutamine ABC transporter (ATP-binding protein) [KO:K10008] [EC:7.4.2.1]
MPLG2_3192  Branched-chain amino acid ABC transporter substrate-binding protein [KO:K01999]
MPLG2_3191  livH; Branched-chain amino acid ABC transporter permease protein [KO:K01997]
MPLG2_3190  livM; Branched-chain amino acid ABC transporter permease protein [KO:K01998]
MPLG2_3189  livG; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995]
MPLG2_3188  livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996]
MPLG2_2478  ABC transporter substrate-binding protein [KO:K13889]
MPLG2_2477  dppB; Dipeptide/oligopeptide/nickel ABC transporter permease [KO:K13890]
MPLG2_2476  protein of unknown function [KO:K13891]
MPLG2_1323  ABC-type Fe3+-hydroxamate transport system periplasmic component-like protein [KO:K25287]
MPLG2_1021  Iron complex transport system substrate-binding protein [KO:K25286]
MPLG2_1020  fepD; iron-enterobactin transporter subunit; membrane component of ABC superfamily [KO:K23186]
MPLG2_1326  fepD; iron-enterobactin transporter subunit; membrane component of ABC superfamily [KO:K23186]
MPLG2_1019  fepG; iron-enterobactin transporter subunit; membrane component of ABC superfamily [KO:K23187]
MPLG2_1325  Iron complex transport system permease protein [KO:K23187]
MPLG2_1018  yusV; iron(III)-siderophore transporter (ATP binding component) [KO:K23188] [EC:7.2.2.17 7.2.2.-]
MPLG2_1324  fecF; iron-dicitrate ABC transporter (ATP-binding protein) [KO:K23188] [EC:7.2.2.17 7.2.2.-]
MPLG2_3528  cbiN; Cobalt transport protein CbiN [KO:K02009]
MPLG2_3527  cbiM; Cobalt transport protein CbiM [KO:K02007]
MPLG2_3529  cbiQ; Cobalt ABC transporter permease protein [KO:K02008]
MPLG2_3530  putative ABC transporter ATP-binding protein in cobA 5'region [KO:K02006]
MPLG2_1758  BioY family transporter [KO:K03523]
MPLG2_1756  Cobalt transport protein [KO:K16783]
MPLG2_1757  putative enzyme [KO:K16784] [EC:7.6.2.-]
MPLG2_2367  conserved membrane protein of unknown function [KO:K16785]
MPLG2_0286  ecfT; Energy-coupling factor transporter transmembrane protein EcfT [KO:K16785]
MPLG2_0287  Cobalt ABC transporter ATP-binding protein [KO:K16786] [EC:7.-.-.-]
MPLG2_0288  putative ABC transporter ATP-binding protein MTBMA_c05830 [KO:K16787] [EC:7.-.-.-]
MPLG2_0078  Transport permease protein [KO:K09690]
MPLG2_0077  tagH; Teichoic acids export ATP-binding protein TagH [KO:K09691] [EC:7.5.2.14]
MPLG2_2621  Transport permease protein [KO:K09692]
MPLG2_2620  Capsular polysaccharide/lipopolysaccharide/teichoic acids ABC transporter ATP-binding subunit [KO:K09693] [EC:7.5.2.4]
MPLG2_2893  Transport permease protein [KO:K09694]
MPLG2_2894  Transport permease protein [KO:K09694]
MPLG2_2895  nodI; Nod factor export ATP-binding protein I [KO:K09695]
MPLG2_1278  Cell division protein FtsX [KO:K09811]
MPLG2_1279  ftsE; cell-division signal transducer (ATP-binding protein) [KO:K09812]
MPLG2_2699  conserved membrane protein of unknown function [KO:K18887]
MPLG2_2700  yfiC; putative ABC transporter (ATP-binding protein) [KO:K18888]
MPLG2_2714  Transport ATP-binding protein CydC [KO:K16012]
MPLG2_2711  Thiol reductant ABC exporter, CydD subunit [KO:K16013]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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