KEGG   PATHWAY: oce02010
Entry
oce02010                    Pathway                                
Name
ABC transporters - Oceanimonas sp. GK1
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
oce02010  ABC transporters
oce02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Oceanimonas sp. GK1 [GN:oce]
Gene
GU3_01790  thiosulfate transporter subunit [KO:K02048]
GU3_01795  sulfate/thiosulfate transporter subunit [KO:K02046]
GU3_01800  cysW; sulfate/thiosulfate transporter permease subunit [KO:K02047]
GU3_01805  sulfate/thiosulfate transporter subunit [KO:K02045] [EC:7.3.2.3]
GU3_07400  molybdenum ABC transporter substrate binding periplasmic protein (ModA) [KO:K02020]
GU3_07405  molybdenum ABC transporter permease (ModB) [KO:K02018]
GU3_07410  molybdate ABC transporter ATPase [KO:K02017] [EC:7.3.2.5]
GU3_10905  putative molybdenum transport ATP-binding protein ModF [KO:K05776]
GU3_01355  2-aminoethylphosphonate ABC transporter substrate-binding protein [KO:K02012]
GU3_15275  iron binding protein FbpA [KO:K02012]
GU3_15615  Fe3+ ABC transporter periplasmic protein [KO:K02012]
GU3_01380  Fe3+ ABC transporter permease [KO:K02011]
GU3_15270  iron(III) ABC transporter permease [KO:K02011]
GU3_01375  2-aminoethylphosphonate ABC transporter ATP-binding protein [KO:K02010] [EC:7.2.2.7]
GU3_15265  iron(III) ABC transporter ATP-binding protein [KO:K02010] [EC:7.2.2.7]
GU3_16065  tbpA; thiamine transporter substrate binding subunit [KO:K02064]
GU3_16070  ABC-type thiamine transporter, permease protein [KO:K02063]
GU3_10195  extracellular solute-binding protein [KO:K11069]
GU3_10200  potC; spermidine/putrescine ABC transporter membrane protein [KO:K11070]
GU3_10205  potB; spermidine/putrescine ABC transporter membrane protein [KO:K11071]
GU3_10210  potA; putrescine/spermidine ABC transporter ATPase protein [KO:K11072] [EC:7.6.2.11]
GU3_11995  putrescine transporter subunit: periplasmic-binding component of ABC superfamily [KO:K11073]
GU3_11980  putrescine transporter subunit: membrane component of ABC superfamily [KO:K11074]
GU3_11985  putrescine transporter subunit: membrane component of ABC superfamily [KO:K11075]
GU3_11990  potG; putrescine transporter ATP-binding subunit [KO:K11076] [EC:7.6.2.16]
GU3_05625  response regulator receiver protein [KO:K02002]
GU3_00375  putative ABC-type proline/glycine betaine transport system periplasmic component [KO:K05845]
GU3_00380  ABC transporter permease [KO:K05846]
GU3_00390  binding-protein-dependent transport system inner membrane protein [KO:K05846]
GU3_00385  ABC transporter [KO:K05847] [EC:7.6.2.9]
GU3_04205  toluene tolerance protein Ttg2D [KO:K07323]
GU3_04040  mammalian cell entry domain-containing protein [KO:K02067]
GU3_04200  mammalian cell entry domain-containing protein [KO:K02067]
GU3_04030  hypothetical protein [KO:K02066]
GU3_04195  ABC transporter permease [KO:K02066]
GU3_04210  anti-anti-sigma factor family protein [KO:K07122]
GU3_04035  ABC transporter-like protein [KO:K02065]
GU3_04190  ABC-type transporter, ATP-binding protein [KO:K02065]
GU3_13845  basic membrane lipoprotein [KO:K07335]
GU3_07540  D-ribose transporter subunit RbsB [KO:K10439]
GU3_07545  rbsC; ribose ABC transporter permease protein [KO:K10440]
GU3_07550  D-ribose transporter ATP binding protein [KO:K10441] [EC:7.5.2.7]
GU3_07555  D-ribose pyranase [KO:K06726] [EC:5.4.99.62]
GU3_13115  phosphate-binding protein [KO:K02040]
GU3_13085  phosphate ABC transporter permease [KO:K02037]
GU3_13080  phosphate ABC transporter, inner membrane subunit PstA [KO:K02038]
GU3_13075  phosphate ABC transporter ATP-binding protein [KO:K02036] [EC:7.3.2.1]
GU3_05000  phosphonate ABC transporter, periplasmic phosphonate-binding protein [KO:K02044]
GU3_05010  binding-protein-dependent transport systems inner membrane component [KO:K02042]
GU3_05005  ABC transporter-like protein [KO:K02041] [EC:7.3.2.2]
GU3_15245  arginine ABC transporter periplasmic arginine-binding protein ArtI [KO:K09997]
GU3_15235  artM; arginine transporter permease subunit ArtM [KO:K09998]
GU3_15240  arginine transporter permease subunit ArtQ [KO:K09999]
GU3_15250  arginine ABC transporter, ATP-binding protein [KO:K10000] [EC:7.4.2.1]
GU3_12085  extracellular solute-binding protein [KO:K09969]
GU3_15410  amino acid ABC transporter periplasmic protein [KO:K09969]
GU3_15415  amino acid ABC transporter permease [KO:K09970]
GU3_15420  amino acid ABC transporter permease [KO:K09971]
GU3_15425  polar amino acid ABC transporter ATPase [KO:K09972] [EC:7.4.2.1]
GU3_01950  polar amino acid ABC transporter periplasmic binding protein [KO:K16961]
GU3_01955  ABC polar amino acid transporter inner membrane protein [KO:K16962]
GU3_01960  phosphate ABC transporter ATP-binding protein [KO:K16963]
GU3_13705  putative amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K10022]
GU3_13695  histidine/lysine/arginine/ornithine ABC transporter permease [KO:K10023]
GU3_13700  amino acid ABC transporter permease [KO:K10024]
GU3_13710  phosphate ABC transporter ATP-binding protein [KO:K10025] [EC:7.4.2.1]
GU3_03260  leucine ABC transporter subunit substrate-binding protein LivK [KO:K01999]
GU3_03265  inner-membrane translocator [KO:K01997]
GU3_03270  livM; leucine/isoleucine/valine transporter permease subunit [KO:K01998]
GU3_03275  livG; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01995]
GU3_03280  branched-chain amino acid ABC transporter ATPase [KO:K01996]
GU3_03930  metQ; DL-methionine transporter substrate-binding subunit [KO:K02073]
GU3_03935  putative ABC-type metal ion transport system,permease component [KO:K02072]
GU3_03940  metN; DL-methionine transporter ATP-binding subunit [KO:K02071]
GU3_08480  ABC-type oligopeptide transporter, periplasmic binding protein [KO:K15580]
GU3_08485  oppB; oligopeptide transporter permease [KO:K15581]
GU3_08490  oligopeptide ABC transporter, permease protein [KO:K15582]
GU3_08495  oppD; oligopeptide transporter ATP-binding component [KO:K15583]
GU3_08500  oligopeptide ABC transporter ATP-binding protein OppF [KO:K10823]
GU3_07585  peptide ABC transporter, periplasmic peptide-binding protein SapA [KO:K19226]
GU3_07580  peptide ABC transporter permease [KO:K19227]
GU3_07575  peptide ABC transporter, permease SapC [KO:K19228]
GU3_07570  peptide ABC transporter ATPase [KO:K19229]
GU3_07565  ABC-type peptide transporter, ATP-binding protein [KO:K19230]
GU3_03955  oligopeptide ABC transporter periplasmic binding protein [KO:K13893]
GU3_03945  oligopeptide transport system permease OppB [KO:K13894]
GU3_03950  ABC-type oligopeptide transport system, permease protein [KO:K13895]
GU3_00505  ABC transporter periplasmic protein [KO:K25286]
GU3_00500  transport system permease protein [KO:K23186]
GU3_00495  transport system permease protein [KO:K23187]
GU3_00490  ABC transporter [KO:K23188] [EC:7.2.2.17 7.2.2.-]
GU3_06325  Fe3+-citrate ABC transporter periplasmic protein [KO:K23227]
GU3_06320  iron-hydroxamate transporter permease subunit [KO:K23228]
GU3_06330  cobalamin/Fe3+-siderophores ABC transporter ATPase [KO:K10829] [EC:7.2.2.16]
GU3_03890  periplasmic binding protein [KO:K06858]
GU3_08240  vtamin B12-transporter permease [KO:K06073]
GU3_08245  ABC transporter [KO:K06074] [EC:7.6.2.8]
GU3_00540  periplasmic solute binding protein [KO:K09815]
GU3_05095  zinc ABC transporter, periplasmic zinc-binding protein [KO:K09815]
GU3_00530  ABC transporter [KO:K09816]
GU3_05105  zinc uptake ABC transporter, permease ZnuB [KO:K09816]
GU3_00535  ABC transporter [KO:K09817] [EC:7.2.2.20]
GU3_05100  high-affinity zinc uptake ABC transporter, ATP-binding protein ZnuC [KO:K09817] [EC:7.2.2.20]
GU3_02035  iron ABC transporter substrate binding protein [KO:K11604]
GU3_02025  ABC-3 protein [KO:K11605]
GU3_02020  iron transmembrane ABC transporter component [KO:K11606]
GU3_02030  iron ABC transporter [KO:K11607]
GU3_14705  hypothetical protein [KO:K10107]
GU3_14695  ABC transporter permease [KO:K09688]
GU3_14700  ABC transporter ATP-binding protein [KO:K09689] [EC:7.6.2.12]
GU3_09220  lipoprotein-releasing system transmembrane protein LolC [KO:K09808]
GU3_09230  lipoprotein releasing system, transmembrane protein LolE [KO:K09808]
GU3_09225  lipoprotein releasing system, ATP-binding protein [KO:K09810] [EC:7.6.2.-]
GU3_13215  hypothetical protein [KO:K02196]
GU3_13220  cytochrome c biogenesis ABC transporter permease [KO:K02195]
GU3_13225  putative heme exporter protein B [KO:K02194]
GU3_13230  ATP binding protein of heme exporter A [KO:K02193] [EC:7.6.2.5]
GU3_04465  putative permease [KO:K07091]
GU3_04470  lipopolysaccharide ABC transporter permease [KO:K11720]
GU3_04165  ABC-type transporter, ATP binding protein [KO:K06861] [EC:7.5.2.5]
GU3_01405  cell division membrane protein FtsX [KO:K09811]
GU3_01410  cell division ATP-binding protein FtsE [KO:K09812]
GU3_09250  lipid A export ATP-binding/permease protein [KO:K11085] [EC:7.5.2.6]
GU3_01570  Fe-S cluster assembly ABC transporter permease/ATPase [KO:K24821]
GU3_11340  putative ABC-type multidrug transport system, ATPase and permease component [KO:K18893]
GU3_12765  toxin secretion ATP-binding protein [KO:K12541]
GU3_00585  macrolide ABC efflux protein [KO:K05685] [EC:7.6.2.-]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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