PATHWAY: pde02010 Help
Entry
Name
ABC transporters - Paracoccus denitrificans
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Paracoccus denitrificans [GN:
pde ]
Gene
Pden_1798 sulfate ABC transporter, periplasmic sulfate-binding protein [KO:K02048 ]
Pden_4344 sulfate ABC transporter, periplasmic sulfate-binding protein [KO:K23163 ]
Pden_5006 aliphatic sulfonates family ABC transporter, periplasmic ligand-binding protein [KO:K15553 ]
Pden_4109 putative sulfonate/nitrate transport system substrate-binding protein [KO:K15553 ]
Pden_4881 Substrate-binding region of ABC-type glycine betaine transport system [KO:K15553 ]
Pden_5005 binding-protein-dependent transport systems inner membrane component [KO:K15554 ]
Pden_4108 binding-protein-dependent transport systems inner membrane component [KO:K15554 ]
Pden_4882 binding-protein-dependent transport systems inner membrane component [KO:K15554 ]
Pden_5011 binding-protein-dependent transport systems inner membrane component [KO:K15554 ]
Pden_0033 binding-protein-dependent transport systems inner membrane component [KO:K15599 ]
Pden_2665 molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
Pden_1167 molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
Pden_4912 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
Pden_4650 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
Pden_4659 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
Pden_4446 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
Pden_1079 binding-protein-dependent transport systems inner membrane component [KO:K02011 ]
Pden_4502 ABC polyamine transporter, periplasmic substrate-binding protein [KO:K11069 ]
Pden_1021 spermidine/putrescine ABC transporter, periplasmic binding protein, putative [KO:K11069 ]
Pden_4067 binding-protein-dependent transport systems inner membrane component [KO:K11070 ]
Pden_1023 binding-protein-dependent transport systems inner membrane component [KO:K11070 ]
Pden_4068 binding-protein-dependent transport systems inner membrane component [KO:K11071 ]
Pden_1022 binding-protein-dependent transport systems inner membrane component [KO:K11071 ]
Pden_3856 Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
Pden_4749 Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
Pden_1195 Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
Pden_0945 Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
Pden_2285 Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
Pden_1899 Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
Pden_3857 binding-protein-dependent transport systems inner membrane component [KO:K02001 ]
Pden_4746 binding-protein-dependent transport systems inner membrane component [KO:K02001 ]
Pden_4747 binding-protein-dependent transport systems inner membrane component [KO:K02001 ]
Pden_1194 binding-protein-dependent transport systems inner membrane component [KO:K02001 ]
Pden_0946 binding-protein-dependent transport systems inner membrane component [KO:K02001 ]
Pden_1900 binding-protein-dependent transport systems inner membrane component [KO:K02001 ]
Pden_4888 Substrate-binding region of ABC-type glycine betaine transport system [KO:K05845 ]
Pden_4885 binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
Pden_4887 binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
Pden_4178 mannitol ABC transporter ATP-binding protein / sorbitol ABC transporter ATP-binding protein [KO:K10111 ] [EC:7.5.2.-]
Pden_4439 carbohydrate ABC transporter ATP-binding protein, CUT1 family [KO:K10111 ] [EC:7.5.2.-]
Pden_2469 carbohydrate ABC transporter ATP-binding protein, CUT1 family [KO:K10111 ] [EC:7.5.2.-]
Pden_4842 carbohydrate ABC transporter ATP-binding protein, CUT1 family [KO:K10111 ] [EC:7.5.2.-]
Pden_1087 carbohydrate ABC transporter ATP-binding protein, CUT1 family [KO:K10112 ] [EC:7.5.2.-]
Pden_3407 carbohydrate ABC transporter ATP-binding protein, CUT1 family [KO:K10112 ] [EC:7.5.2.-]
Pden_1050 carbohydrate ABC transporter ATP-binding protein, CUT1 family [KO:K10112 ] [EC:7.5.2.-]
Pden_2472 carbohydrate ABC transporter substrate-binding protein, CUT1 family [KO:K10117 ]
Pden_2471 carbohydrate ABC transporter membrane protein 1, CUT1 family [KO:K10118 ]
Pden_2470 carbohydrate ABC transporter membrane protein 2, CUT1 family [KO:K10119 ]
Pden_4180 mannitol ABC transporter membrane protein / sorbitol ABC transporter membrane protein [KO:K10228 ]
Pden_4844 mannitol ABC transporter membrane protein / sorbitol ABC transporter membrane protein [KO:K10228 ]
Pden_4179 sorbitol ABC transporter membrane protein / mannitol ABC transporter membrane protein [KO:K10229 ]
Pden_4843 sorbitol ABC transporter membrane protein / mannitol ABC transporter membrane protein [KO:K10229 ]
Pden_4442 carbohydrate ABC transporter substrate-binding protein, CUT1 family [KO:K10236 ]
Pden_4441 carbohydrate ABC transporter membrane protein 1, CUT1 family [KO:K10237 ]
Pden_4440 carbohydrate ABC transporter membrane protein 2, CUT1 family [KO:K10238 ]
Pden_2747 multiple monosaccharide ABC transporter membrane protein [KO:K10547 ]
Pden_2746 multiple monosaccharide ABC transporter ATP-binding protein [KO:K10548 ] [EC:7.5.2.-]
Pden_3404 carbohydrate ABC transporter substrate-binding protein, CUT1 family [KO:K17315 ]
Pden_1090 carbohydrate ABC transporter substrate-binding protein, CUT1 family [KO:K17315 ]
Pden_3405 carbohydrate ABC transporter membrane protein 1, CUT1 family [KO:K17316 ]
Pden_1089 carbohydrate ABC transporter membrane protein 1, CUT1 family [KO:K17316 ]
Pden_1088 carbohydrate ABC transporter membrane protein 2, CUT1 family [KO:K17317 ]
Pden_3406 carbohydrate ABC transporter membrane protein 2, CUT1 family [KO:K17317 ]
Pden_4771 monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K10439 ]
Pden_2160 monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K10439 ]
Pden_4851 monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K10439 ]
Pden_0247 monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K10439 ]
Pden_4770 monosaccharide ABC transporter membrane protein, CUT2 family [KO:K10440 ]
Pden_2158 monosaccharide ABC transporter membrane protein, CUT2 family [KO:K10440 ]
Pden_4849 monosaccharide ABC transporter membrane protein, CUT2 family [KO:K10440 ]
Pden_0249 monosaccharide ABC transporter membrane protein, CUT2 family [KO:K10440 ]
Pden_1032 monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K10543 ]
Pden_0505 mannose-binding protein / fructose-binding protein / ribose-binding protein [KO:K10552 ]
Pden_0504 fructose ABC transporter membrane protein / mannose ABC transporter membrane protein / ribose ABC transporter membrane protein [KO:K10553 ]
Pden_0503 ribose ABC transporter ATP-binding protein / fructose ABC transporter ATP-binding protein / mannose ABC transporter ATP-binding protein [KO:K10554 ]
Pden_1681 monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K17213 ]
Pden_1684 monosaccharide ABC transporter substrate-binding protein, CUT2 family [KO:K17213 ]
Pden_1682 monosaccharide ABC transporter membrane protein, CUT2 family [KO:K17214 ]
Pden_1683 monosaccharide ABC transporter ATP-binding protein, CUT2 family [KO:K17215 ]
Pden_4387 carbohydrate ABC transporter substrate-binding protein, CUT1 family [KO:K17321 ]
Pden_4390 carbohydrate ABC transporter membrane protein 1, CUT1 family [KO:K17322 ]
Pden_4389 carbohydrate ABC transporter membrane protein 2, CUT1 family [KO:K17323 ]
Pden_4392 carbohydrate ABC transporter ATP-binding protein, CUT1 family [KO:K17324 ]
Pden_4391 carbohydrate ABC transporter ATP-binding protein, CUT1 family [KO:K17325 ]
Pden_4190 carbohydrate ABC transporter substrate-binding protein, CUT1 family [KO:K05813 ]
Pden_4189 carbohydrate ABC transporter membrane protein 1, CUT1 family [KO:K05814 ]
Pden_4188 carbohydrate ABC transporter membrane protein 2, CUT1 family [KO:K05815 ]
Pden_4330 phosphate ABC transporter substrate-binding protein, PhoT family [KO:K02040 ]
Pden_4329 phosphate ABC transporter membrane protein 1, PhoT family [KO:K02037 ]
Pden_4328 phosphate ABC transporter membrane protein 2, PhoT family [KO:K02038 ]
Pden_4786 phosphonate ABC transporter, periplasmic phosphonate-binding protein [KO:K02044 ]
Pden_1072 L-glutamate-binding protein / L-aspartate-binding protein [KO:K10001 ]
Pden_1074 L-aspartate ABC transporter membrane protein / L-glutamate ABC transporter membrane protein [KO:K10002 ]
Pden_1073 L-glutamate ABC transporter membrane protein / L-aspartate ABC transporter membrane protein [KO:K10003 ]
Pden_0793 L-aspartate-binding protein / L-glutamate-binding protein / L-glutamine-binding protein / L-asparagine-binding protein [KO:K09969 ]
Pden_0794 L-asparagine ABC transporter membrane protein / L-glutamine ABC transporter membrane protein / L-glutamate ABC transporter membrane protein / L-aspartate ABC transporter membrane protein [KO:K09970 ]
Pden_0795 L-glutamate ABC transporter membrane protein / L-asparagine ABC transporter membrane protein / L-glutamine ABC transporter membrane protein / L-aspartate ABC transporter membrane protein [KO:K09971 ]
Pden_0796 L-aspartate ABC transporter ATP-binding protein / L-glutamine ABC transporter ATP-binding protein / L-glutamate ABC transporter ATP-binding protein / L-asparagine ABC transporter ATP-binding protein [KO:K09972 ] [EC:7.4.2.1 ]
Pden_4864 amino acid ABC transporter substrate-binding protein, PAAT family [KO:K23061 ]
Pden_1025 amino acid ABC transporter substrate-binding protein, PAAT family [KO:K23061 ]
Pden_4863 amino acid ABC transporter membrane protein 1, PAAT family [KO:K23062 ]
Pden_1026 amino acid ABC transporter membrane protein 1, PAAT family [KO:K23062 ]
Pden_4862 amino acid ABC transporter membrane protein 2, PAAT family [KO:K23063 ]
Pden_1027 amino acid ABC transporter membrane protein 2, PAAT family [KO:K23063 ]
Pden_3932 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_5095 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_4797 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_0052 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_4272 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_1717 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_4869 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_3574 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_0175 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_3054 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_4994 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K01999 ]
Pden_3929 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_5096 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_4796 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_4271 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_1714 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_0050 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_0176 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_3057 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_3575 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_5000 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K01997 ]
Pden_3928 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_5097 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_4795 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_0051 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_4270 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_1713 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_0177 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_3058 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_4999 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K01998 ]
Pden_3576 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family / amino acid/amide ABC transporter membrane protein 2, HAAT family / amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 K01996 K01998 ]
Pden_3931 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_5098 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_3055 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_4998 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_4794 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_0049 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_4269 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_1716 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_0178 amino acid/amide ABC transporter ATP-binding protein 1, HAAT family [KO:K01995 ]
Pden_3930 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_5099 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_3056 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_4793 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_0053 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_4268 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_1715 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_0179 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_4997 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K01996 ]
Pden_4307 binding-protein-dependent transport systems inner membrane component [KO:K02072 ]
Pden_4017 amino acid/amide ABC transporter substrate-binding protein, HAAT family [KO:K11959 ]
Pden_4018 amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K11960 ]
Pden_4019 amino acid/amide ABC transporter membrane protein 2, HAAT family [KO:K11961 ]
Pden_4021 amino acid/amide ABC transporter ATP-binding protein 2, HAAT family [KO:K11963 ]
Pden_1570 binding-protein-dependent transport systems inner membrane component [KO:K15581 ]
Pden_1327 binding-protein-dependent transport systems inner membrane component [KO:K15581 ]
Pden_1326 binding-protein-dependent transport systems inner membrane component [KO:K15582 ]
Pden_1571 binding-protein-dependent transport systems inner membrane component [KO:K15582 ]
Pden_1572 oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K15583 ]
Pden_1325 oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K15583 ]
Pden_1573 oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K10823 ]
Pden_1324 oligopeptide/dipeptide ABC transporter, ATPase subunit [KO:K10823 ]
Pden_1670 binding-protein-dependent transport systems inner membrane component [KO:K12369 ]
Pden_1669 binding-protein-dependent transport systems inner membrane component [KO:K12370 ]
Pden_1806 binding-protein-dependent transport systems inner membrane component [KO:K13894 ]
Pden_1805 binding-protein-dependent transport systems inner membrane component [KO:K13895 ]
Pden_1840 lipoprotein releasing system, transmembrane protein, LolC/E family [KO:K09808 ]
Pden_4346 colicin V processing peptidase, Cysteine peptidase, MEROPS family C39 [KO:K13409 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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