KEGG   PATHWAY: pviv04136
Entry
pviv04136                   Pathway                                
Name
Autophagy - other - Prionailurus viverrinus (fishing cat)
Description
Autophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either in a housekeeping capacity or during stress and senescence. The process of autophagy could be divided into several stages: induction, vesicle nucleation, elongation and closure, and fusion and digestion. Most essential autophagic machineries are conserved throughout eukaryotes (see map04140 for animals and map04138 for fungi). This map is for other eukaryotes including plants and protists, where autophagy related genes (ATGs) play similar roles in the life cycle. However, autophagy has been relatively less studied in lower eukaryotes.
Class
Cellular Processes; Transport and catabolism
Pathway map
pviv04136  Autophagy - other
pviv04136

Other DBs
GO: 0006914
Organism
Prionailurus viverrinus (fishing cat) [GN:pviv]
Gene
125152176  RPTOR; regulatory-associated protein of mTOR isoform X1 [KO:K07204]
125172574  MTOR; serine/threonine-protein kinase mTOR isoform X1 [KO:K07203] [EC:2.7.11.1]
125154788  MLST8; target of rapamycin complex subunit LST8 [KO:K08266]
125151280  ULK2; serine/threonine-protein kinase ULK2 isoform X1 [KO:K08269] [EC:2.7.11.1]
125176545  ATG13; autophagy-related protein 13 isoform X1 [KO:K08331]
125171066  ATG101; autophagy-related protein 101 isoform X1 [KO:K19730]
125157578  IGBP1; immunoglobulin-binding protein 1 [KO:K17606]
125150627  immunoglobulin-binding protein 1-like [KO:K17606]
125164370  PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [KO:K04382] [EC:3.1.3.16]
125172646  PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform [KO:K04382] [EC:3.1.3.16]
125154201  ATG9B; autophagy-related protein 9B [KO:K17907]
125172795  ATG9A; autophagy-related protein 9A [KO:K17907]
125168852  ATG2B; autophagy-related protein 2 homolog B isoform X1 [KO:K17906]
125177194  ATG2A; autophagy-related protein 2 homolog A isoform X1 [KO:K17906]
125151335  WIPI1; WD repeat domain phosphoinositide-interacting protein 1 [KO:K17908]
125154170  WIPI2; WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [KO:K17908]
125158472  BECN1; beclin-1 isoform X1 [KO:K08334]
125155851  BECN2; beclin-2 [KO:K08334]
125149250  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
125175178  PIK3R4; phosphoinositide 3-kinase regulatory subunit 4 [KO:K08333] [EC:2.7.11.1]
125165366  ATG12; ubiquitin-like protein ATG12 isoform X1 [KO:K08336]
125165963  ATG5; autophagy protein 5 isoform X1 [KO:K08339]
125172389  ATG16L1; autophagy-related protein 16-1 isoform X1 [KO:K17890]
125153026  ATG7; ubiquitin-like modifier-activating enzyme ATG7 isoform X1 [KO:K08337]
125167675  ATG10; ubiquitin-like-conjugating enzyme ATG10 isoform X1 [KO:K17888]
125174837  ATG3; ubiquitin-like-conjugating enzyme ATG3 [KO:K08343]
125151526  GABARAP; gamma-aminobutyric acid receptor-associated protein [KO:K08341]
125152679  GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2 [KO:K08341]
125170954  GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 [KO:K08341]
125158941  ATG4B; cysteine protease ATG4B isoform X1 [KO:K08342] [EC:3.4.22.-]
125152396  ATG4D; cysteine protease ATG4D isoform X1 [KO:K08342] [EC:3.4.22.-]
125157609  ATG4A; cysteine protease ATG4A isoform X1 [KO:K08342] [EC:3.4.22.-]
125173304  ATG4C; cysteine protease ATG4C isoform X1 [KO:K08342] [EC:3.4.22.-]
Compound
C00350  Phosphatidylethanolamine
C01194  1-Phosphatidyl-D-myo-inositol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
Reference
  Authors
Duszenko M, Ginger ML, Brennand A, Gualdron-Lopez M, Colombo MI, Coombs GH, Coppens I, Jayabalasingham B, Langsley G, de Castro SL, Menna-Barreto R, Mottram JC, Navarro M, Rigden DJ, Romano PS, Stoka V, Turk B, Michels PA
  Title
Autophagy in protists.
  Journal
Autophagy 7:127-58 (2011)
DOI:10.4161/auto.7.2.13310
Reference
  Authors
Avin-Wittenberg T, Honig A, Galili G
  Title
Variations on a theme: plant autophagy in comparison to yeast and mammals.
  Journal
Protoplasma 249:285-99 (2012)
DOI:10.1007/s00709-011-0296-z
Reference
  Authors
Liu Y, Bassham DC
  Title
Autophagy: pathways for self-eating in plant cells.
  Journal
Annu Rev Plant Biol 63:215-37 (2012)
DOI:10.1146/annurev-arplant-042811-105441
Reference
  Authors
Yoshimoto K
  Title
Beginning to understand autophagy, an intracellular self-degradation system in plants.
  Journal
Plant Cell Physiol 53:1355-65 (2012)
DOI:10.1093/pcp/pcs099
Reference
  Authors
Li F, Chung T, Vierstra RD
  Title
AUTOPHAGY-RELATED11 plays a critical role in general autophagy- and senescence-induced mitophagy in Arabidopsis.
  Journal
Plant Cell 26:788-807 (2014)
DOI:10.1105/tpc.113.120014
Reference
  Authors
Michaeli S, Galili G, Genschik P, Fernie AR, Avin-Wittenberg T
  Title
Autophagy in Plants--What's New on the Menu?
  Journal
Trends Plant Sci 21:134-44 (2016)
DOI:10.1016/j.tplants.2015.10.008
Reference
  Authors
Yang X, Bassham DC
  Title
New Insight into the Mechanism and Function of Autophagy in Plant Cells.
  Journal
Int Rev Cell Mol Biol 320:1-40 (2015)
DOI:10.1016/bs.ircmb.2015.07.005
KO pathway
ko04136   
LinkDB

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