Entry
Name
ABC transporters - Rhodococcus erythropolis PR4
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Rhodococcus erythropolis PR4 [GN:
rer ]
Gene
RER_37560 subI; sulfate ABC transporter sulfate-binding protein [KO:K23163 ]
RER_58610 ssuA; putative aliphatic sulfonates ABC transporter substrate-binding protein [KO:K15553 ]
RER_58540 ssuA; putative aliphatic sulfonates ABC transporter substrate-binding protein [KO:K15553 ]
RER_58550 ssuC; putative aliphatic sulfonates ABC transporter permease protein [KO:K15554 ]
RER_46710 modA; putative molybdate ABC transporter molybdate-binding protein [KO:K02020 ]
RER_46700 modB; putative molybdate ABC transporter permease protein [KO:K02018 ]
RER_36840 putative ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
RER_59040 putative ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
RER_41440 putative ABC transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
RER_48040 pstS; phosphate ABC transporter phosphate-binding protein [KO:K02040 ]
RER_43630 glnH_glnP; putative glutamine ABC transporter glutamine-binding/permease protein [KO:K10036 K10037 ]
RER_27570 gluB; glutamate ABC transporter glutamate-binding protein [KO:K10005 ]
RER_13550 putative branched-chain amino acid ABC transporter amino acid-binding protein [KO:K01999 ]
RER_13560 putative branched-chain amino acid ABC transporter permease protein [KO:K01997 ]
RER_13570 putative branched-chain amino acid ABC transporter permease/ATP-binding protein [KO:K01995 K01998 ]
RER_13580 putative branched-chain amino acid ABC transporter ATP-binding protein [KO:K01996 ]
RER_57370 putative iron-siderophore ABC transporter substrate-binding protein [KO:K23185 ]
RER_03160 putative iron-siderophore ABC transporter substrate-binding protein [KO:K25286 ]
RER_03170 putative iron-siderophore ABC transporter permease protein [KO:K23186 ]
RER_31080 putative iron-siderophore ABC transporter permease protein [KO:K23186 ]
RER_57360 putative iron-siderophore ABC transporter permease protein [KO:K23186 ]
RER_57350 putative iron-siderophore ABC transporter permease protein [KO:K23187 ]
RER_03180 putative iron-siderophore ABC transporter permease protein [KO:K23187 ]
RER_31070 putative iron-siderophore ABC transporter permease protein [KO:K23187 ]
RER_59770 mntC; manganese ABC transporter manganese-binding protein [KO:K11601 ]
RER_59750 mntB; putative manganese ABC transporter permease protein [KO:K11602 ]
RER_27450 putative ABC transporter ATP-binding protein [KO:K16784 ] [EC:7.6.2.-]
RER_51400 putative ABC transporter ATP-binding protein [KO:K09814 ] [EC:7.6.2.-]
RER_01010 putative ABC transporter ATP-binding protein [KO:K09814 ] [EC:7.6.2.-]
RER_43350 putative iron-siderophore ABC transporter permease/ATP-binding protein [KO:K14698 ] [EC:7.-.-.-]
RER_53710 putative iron-siderophore ABC transporter permease/ATP-binding protein [KO:K14698 ] [EC:7.-.-.-]
RER_43340 putative iron-siderophore ABC transporter permease/ATP-binding protein [KO:K14699 ] [EC:7.-.-.-]
RER_53700 putative iron-siderophore ABC transporter permease/ATP-binding protein [KO:K14699 ] [EC:7.-.-.-]
RER_03410 putative ABC transporter permease/ATP-binding protein [KO:K18887 ]
RER_14350 putative ABC transporter permease/ATP-binding protein [KO:K18887 ]
RER_03420 putative ABC transporter permease/ATP-binding protein [KO:K18888 ]
RER_14340 putative ABC transporter permease/ATP-binding protein [KO:K18888 ]
RER_48150 cydC; putative ABC transporter permease/ATP-binding protein CydC [KO:K16012 ]
RER_48160 cydD; putative ABC transporter permease/ATP-binding protein CydD [KO:K16013 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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