Entry
Name
ABC transporters - Tepidanaerobacter acetatoxydans Re1
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Tepidanaerobacter acetatoxydans Re1 [GN:
tae ]
Gene
TepiRe1_0643 msmX; multiple sugar-binding transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
TepiRe1_0707 rbsC; D-ribose transporter subunit; membrane component of ABC superfamily [KO:K10440 ]
TepiRe1_0808 mglB; methyl-galactoside transporter subunit; periplasmic-binding component of ABC superfamily [KO:K10540 ]
TepiRe1_1981 mglB; methyl-galactoside transporter subunit; periplasmic-binding component of ABC superfamily [KO:K10540 ]
TepiRe1_0810 mglC; methyl-galactoside transporter subunit; membrane component of ABC superfamily [KO:K10541 ]
TepiRe1_1979 mglC; methyl-galactoside transporter subunit; membrane component of ABC superfamily [KO:K10541 ]
TepiRe1_0809 mglA; fused methyl-galactoside transporter subunits of ABC superfamily: ATP-binding components [KO:K10542 ] [EC:7.5.2.11 ]
TepiRe1_1980 mglA; fused methyl-galactoside transporter subunits of ABC superfamily: ATP-binding components [KO:K10542 ] [EC:7.5.2.11 ]
TepiRe1_1982 xylF; D-xylose transporter subunit; periplasmic-binding component of ABC superfamily [KO:K10543 ]
TepiRe1_2116 hisP; histidine/lysine/arginine/ornithine transporter subunit; ATP-binding component of ABC superfamily [KO:K17076 ]
TepiRe1_0431 livH; leucine/isoleucine/valine transporter subunit; membrane component of ABC superfamily [KO:K01997 ]
TepiRe1_1742 livH; leucine/isoleucine/valine transporter subunit; membrane component of ABC superfamily [KO:K01997 ]
TepiRe1_1741 livM; High-affinity branched-chain amino acid transport system permease protein LivM [KO:K01998 ]
TepiRe1_0429 livG; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995 ]
TepiRe1_1884 livG; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995 ]
TepiRe1_1951 livG; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995 ]
TepiRe1_1740 livG; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01995 ]
TepiRe1_0428 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
TepiRe1_1739 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
TepiRe1_1883 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
TepiRe1_1950 livF; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily [KO:K01996 ]
TepiRe1_0042 oppB; oligopeptide transporter subunit; membrane component of ABC superfamily [KO:K15581 ]
TepiRe1_0045 ykfD; putative cell wall oligopeptide ABC transporter (ATP binding protein) [KO:K10823 ]
TepiRe1_0232 ecfA; Energy-coupling factor transporter ATP-binding protein EcfA 2 [KO:K16786 ] [EC:7.-.-.-]
TepiRe1_0234 energizing coupling factor of ABC influx transporter (ATP-binding protein) (fragment) [KO:K16787 ] [EC:7.-.-.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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