KEGG   PATHWAY: vra04626
Entry
vra04626                    Pathway                                
Name
Plant-pathogen interaction - Vigna radiata (mung bean)
Description
Plants lack animal-like adaptive immunity mechanisms, and therefore have evolved a specific system with multiple layers against invading pathogens. The primary response includes the perception of pathogens by cell-surface pattern-recognition receptors (PRRs) and is referred to as PAMP-triggered immunity (PTI). Activation of FLS2 and EFR triggers MAPK signaling pathway that activates defense genes for antimictobial compounds. The increase in the cytosolic Ca2+ concentration is also a regulator for production of reactive oxygen species and localized programmed cell death/hypersensitive response. The secondary response is called effector-triggered immunity (ETI). Pathogens can acquire the ability to suppress PTI by directly injecting effector proteins into the plant cell through secretion systems. In addition, pathogens can manipulate plant hormone signaling pathways to evade host immune responses using coronatine toxin. Some plants possess specific intracellular surveillance proteins (R proteins) to monitor the presence of pathogen virulence proteins. This ETI occurs with localized programmed cell death to arrest pathogen growth, resulting in cultivar-specific disease resistance.
Class
Organismal Systems; Environmental adaptation
Pathway map
vra04626  Plant-pathogen interaction
vra04626

Organism
Vigna radiata (mung bean) [GN:vra]
Gene
106753197  calcium-dependent protein kinase SK5 [KO:K13412] [EC:2.7.11.1]
106754669  calcium and calcium/calmodulin-dependent serine/threonine-protein kinase [KO:K13412] [EC:2.7.11.1]
106757064  calcium-dependent protein kinase 1 [KO:K13412] [EC:2.7.11.1]
106778483  calcium-dependent protein kinase 24 [KO:K13412] [EC:2.7.11.1]
106766738  calcium-dependent protein kinase 10 [KO:K13412] [EC:2.7.11.1]
106769066  calcium-dependent protein kinase 28 isoform X1 [KO:K13412] [EC:2.7.11.1]
106768380  calcium-dependent protein kinase 2 [KO:K13412] [EC:2.7.11.1]
106763852  calcium-dependent protein kinase 26 [KO:K13412] [EC:2.7.11.1]
106765233  calcium-dependent protein kinase 2 isoform X1 [KO:K13412] [EC:2.7.11.1]
106770752  calcium-dependent protein kinase 26 [KO:K13412] [EC:2.7.11.1]
106777871  calcium-dependent protein kinase 3 isoform X1 [KO:K13412] [EC:2.7.11.1]
106779043  calcium-dependent protein kinase 13 [KO:K13412] [EC:2.7.11.1]
106767050  calcium-dependent protein kinase 1 [KO:K13412] [EC:2.7.11.1]
106768224  calcium-dependent protein kinase SK5 [KO:K13412] [EC:2.7.11.1]
106765097  calcium-dependent protein kinase 29 isoform X1 [KO:K13412] [EC:2.7.11.1]
106771279  calcium-dependent protein kinase 32 [KO:K13412] [EC:2.7.11.1]
106770988  calcium-dependent protein kinase 4 [KO:K13412] [EC:2.7.11.1]
106772133  calcium-dependent protein kinase 1 [KO:K13412] [EC:2.7.11.1]
106757712  calcium-dependent protein kinase 32 [KO:K13412] [EC:2.7.11.1]
106772715  calcium-dependent protein kinase 4 isoform X2 [KO:K13412] [EC:2.7.11.1]
106764709  calcium-dependent protein kinase 2 [KO:K13412] [EC:2.7.11.1]
106765905  calcium-dependent protein kinase 17-like [KO:K13412] [EC:2.7.11.1]
106777786  calcium-dependent protein kinase 28-like [KO:K13412] [EC:2.7.11.1]
106765152  calcium-dependent protein kinase 2 [KO:K13412] [EC:2.7.11.1]
106772233  calcium-dependent protein kinase 20-like [KO:K13412] [EC:2.7.11.1]
106778757  calcium-dependent protein kinase 10 [KO:K13412] [EC:2.7.11.1]
106754356  calcium-dependent protein kinase 2 [KO:K13412] [EC:2.7.11.1]
106768788  CDPK-related kinase 5 isoform X2 [KO:K13412] [EC:2.7.11.1]
106772198  CDPK-related kinase 7 [KO:K13412] [EC:2.7.11.1]
106780369  CDPK-related kinase 3 [KO:K13412] [EC:2.7.11.1]
106776172  CDPK-related kinase 6 [KO:K13412] [EC:2.7.11.1]
106753930  CDPK-related kinase 7 isoform X1 [KO:K13412] [EC:2.7.11.1]
106775899  respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.6.3.- 1.11.1.-]
106777710  respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.6.3.- 1.11.1.-]
106768745  respiratory burst oxidase homolog protein C isoform X1 [KO:K13447] [EC:1.6.3.- 1.11.1.-]
106768869  respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.6.3.- 1.11.1.-]
106772356  respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.6.3.- 1.11.1.-]
106760800  respiratory burst oxidase homolog protein E [KO:K13447] [EC:1.6.3.- 1.11.1.-]
106768261  respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.6.3.- 1.11.1.-]
106761966  respiratory burst oxidase homolog protein C [KO:K13447] [EC:1.6.3.- 1.11.1.-]
106754139  cyclic nucleotide-gated ion channel 1 [KO:K05391]
106756531  protein CNGC15a isoform X1 [KO:K05391]
106777396  protein CNGC15b [KO:K05391]
106761905  cyclic nucleotide-gated ion channel 17-like [KO:K05391]
106758827  cyclic nucleotide-gated ion channel 18 [KO:K05391]
106770587  probable cyclic nucleotide-gated ion channel 20, chloroplastic [KO:K05391]
106770601  probable cyclic nucleotide-gated ion channel 20, chloroplastic [KO:K05391]
106770771  probable cyclic nucleotide-gated ion channel 20, chloroplastic isoform X1 [KO:K05391]
106758934  protein CNGC15c [KO:K05391]
106774177  cyclic nucleotide-gated ion channel 1 [KO:K05391]
106761313  probable cyclic nucleotide-gated ion channel 14 [KO:K05391]
106764917  cyclic nucleotide-gated ion channel 1 [KO:K05391]
106768428  probable cyclic nucleotide-gated ion channel 5 [KO:K05391]
106778896  cyclic nucleotide-gated ion channel 1 isoform X1 [KO:K05391]
106760241  probable cyclic nucleotide-gated ion channel 16 [KO:K05391]
106759266  cyclic nucleotide-gated ion channel 2 [KO:K05391]
106773054  putative cyclic nucleotide-gated ion channel 7 [KO:K05391]
111242080  probable cyclic nucleotide-gated ion channel 20, chloroplastic [KO:K05391]
106756202  cyclic nucleotide-gated ion channel 4 [KO:K05391]
106753881  calmodulin-7 [KO:K02183]
106757626  calmodulin-3 [KO:K02183]
106758782  probable calcium-binding protein CML45 [KO:K02183]
106771662  calmodulin [KO:K02183]
106778683  calmodulin [KO:K02183]
106764875  calmodulin [KO:K02183]
106767572  calmodulin [KO:K02183]
106771724  calmodulin-like protein 11 [KO:K02183]
106770751  neo-calmodulin isoform X1 [KO:K02183]
106752538  probable calcium-binding protein CML35 [KO:K13448]
106753701  calmodulin-like protein 3 [KO:K13448]
106753627  probable calcium-binding protein CML15 [KO:K13448]
106753873  putative calcium-binding protein CML19 [KO:K13448]
106752736  calcium-binding protein CML38 [KO:K13448]
106755511  probable calcium-binding protein CML18 [KO:K13448]
106755618  calmodulin-like protein 3 [KO:K13448]
106757538  polcalcin Che a 3 [KO:K13448]
106764412  probable calcium-binding protein CML44 [KO:K13448]
106767904  probable calcium-binding protein CML13 isoform X2 [KO:K13448]
106765731  probable calcium-binding protein CML21 [KO:K13448]
106772778  probable calcium-binding protein CML49 [KO:K13448]
106762598  probable calcium-binding protein CML44 [KO:K13448]
106767440  probable calcium-binding protein CML41 [KO:K13448]
106761668  probable calcium-binding protein CML41 [KO:K13448]
106764083  probable calcium-binding protein CML23 [KO:K13448]
106777218  calmodulin-like protein 1 [KO:K13448]
106773021  probable calcium-binding protein CML13 [KO:K13448]
106759275  probable calcium-binding protein CML27 [KO:K13448]
106767974  probable calcium-binding protein CML25 [KO:K13448]
106758988  calcium-binding protein CML42 [KO:K13448]
106777071  probable calcium-binding protein CML13 [KO:K13448]
106779399  calmodulin-like protein 3 [KO:K13448]
106778452  calmodulin-like protein 7 [KO:K13448]
106775248  probable calcium-binding protein CML20 [KO:K13448]
106767275  calmodulin-like protein 1 [KO:K13448]
106768467  probable calcium-binding protein CML15 [KO:K13448]
106770817  calmodulin-like protein 11 [KO:K13448]
106771212  calmodulin-like protein 8 [KO:K13448]
106780590  probable calcium-binding protein CML48 isoform X1 [KO:K13448]
106757942  calcium-binding protein CML24 [KO:K13448]
106763935  probable calcium-binding protein CML26 [KO:K13448]
106764558  polcalcin Ole e 3 [KO:K13448]
106768067  polcalcin Phl p 7-like [KO:K13448]
106768082  putative calcium-binding protein CML19 [KO:K13448]
106777407  probable calcium-binding protein CML25 [KO:K13448]
106767342  probable calcium-binding protein CML16 [KO:K13448]
106779496  probable calcium-binding protein CML22 [KO:K13448]
106767556  probable calcium-binding protein CML31 [KO:K13448]
106779222  NO-associated protein 1, chloroplastic/mitochondrial [KO:K13427] [EC:1.14.13.39]
106774046  mitogen-activated protein kinase homolog MMK2 [KO:K20600] [EC:2.7.11.24]
106752886  LRR receptor-like serine/threonine-protein kinase FLS2 [KO:K13420] [EC:2.7.11.1]
106775803  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 [KO:K13416] [EC:2.7.10.1 2.7.11.1]
106774250  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 [KO:K13416] [EC:2.7.10.1 2.7.11.1]
106774068  BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1-like isoform X1 [KO:K13416] [EC:2.7.10.1 2.7.11.1]
106753327  elongation factor Tu, chloroplastic [KO:K02358]
106756705  elongation factor Tu, mitochondrial [KO:K02358]
106762657  elongation factor Tu, chloroplastic [KO:K02358]
106774426  elongation factor Tu, mitochondrial [KO:K02358]
106764653  mitogen-activated protein kinase kinase kinase 1 isoform X1 [KO:K13414] [EC:2.7.11.25]
106762341  mitogen-activated protein kinase kinase kinase 1-like [KO:K13414] [EC:2.7.11.25]
106763728  mitogen-activated protein kinase kinase 6 [KO:K04368] [EC:2.7.12.2]
106774137  LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase 5-like [KO:K13413] [EC:2.7.12.2]
106756058  mitogen-activated protein kinase 3 [KO:K20536] [EC:2.7.11.24]
106768762  mitogen-activated protein kinase homolog MMK1 [KO:K14512] [EC:2.7.11.24]
106752427  WRKY transcription factor WRKY24 [KO:K13424]
106755105  probable WRKY transcription factor 33 [KO:K13424]
106755495  probable WRKY transcription factor 33 isoform X1 [KO:K13424]
106764873  WRKY transcription factor WRKY24 [KO:K13424]
106773888  WRKY transcription factor 22 [KO:K13425]
106758133  WRKY transcription factor 22 [KO:K13425]
106766668  probable WRKY transcription factor 29 [KO:K13426]
106772897  glycerol kinase [KO:K00864] [EC:2.7.1.30]
106765569  basic form of pathogenesis-related protein 1-like [KO:K13449]
106775457  basic form of pathogenesis-related protein 1 [KO:K13449]
106775458  basic form of pathogenesis-related protein 1 [KO:K13449]
106775533  pathogenesis-related genes transcriptional activator PTI5 [KO:K13433]
106775950  pathogenesis-related genes transcriptional activator PTI6 [KO:K13434]
106763139  pathogenesis-related genes transcriptional activator PTI6-like [KO:K13434]
106754859  pto-interacting protein 1 [KO:K13436] [EC:2.7.11.1]
106756672  pto-interacting protein 1 [KO:K13436] [EC:2.7.11.1]
106766730  pto-interacting protein 1 isoform X1 [KO:K13436] [EC:2.7.11.1]
106772472  PTI1-like tyrosine-protein kinase 3 isoform X2 [KO:K13436] [EC:2.7.11.1]
106774889  RPM1-interacting protein 4 [KO:K13456]
106759470  RPM1-interacting protein 4 [KO:K13456]
106774344  RPM1-interacting protein 4 [KO:K13456]
106775361  disease resistance protein RPM1-like isoform X1 [KO:K13457]
106779171  disease resistance protein RPM1-like [KO:K13457]
106775818  disease resistance protein RPM1 [KO:K13457]
106774736  disease resistance protein RPM1 [KO:K13457]
106777972  disease resistance protein RPM1 [KO:K13457]
106777987  disease resistance protein RPM1 [KO:K13457]
106772275  cysteine and histidine-rich domain-containing protein RAR1 [KO:K13458]
106774071  protein SGT1 homolog B isoform X1 [KO:K12795]
106776377  protein SGT1 homolog A [KO:K12795]
106777668  heat shock protein 90-5, chloroplastic isoform X1 [KO:K09487]
106764678  heat shock protein 90-6, mitochondrial [KO:K09487]
106764918  endoplasmin homolog [KO:K09487]
106773454  heat shock protein 83 [KO:K04079]
106764799  heat shock cognate protein 80 [KO:K04079]
106763355  disease resistance protein RPS2-like [KO:K13459]
106780295  probable disease resistance protein At4g27220 [KO:K13459]
106758642  serine/threonine-protein kinase PBS1 [KO:K13430] [EC:2.7.11.1]
106772190  serine/threonine-protein kinase PBS1 [KO:K13430] [EC:2.7.11.1]
106758819  probable serine/threonine-protein kinase PBL7 [KO:K13430] [EC:2.7.11.1]
106759504  protein EDS1L [KO:K18875]
106759556  protein EDS1L [KO:K18875]
106754659  cysteine protease RD19A [KO:K01373] [EC:3.4.22.41]
106771338  probable cysteine protease RD19D [KO:K01373] [EC:3.4.22.41]
106762220  cysteine proteinase 15A [KO:K01373] [EC:3.4.22.41]
106765046  cysteine proteinase 15A [KO:K01373] [EC:3.4.22.41]
106756415  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
106772800  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
106776817  3-ketoacyl-CoA synthase 12 [KO:K15397] [EC:2.3.1.199]
106758797  3-ketoacyl-CoA synthase 12 [KO:K15397] [EC:2.3.1.199]
106762302  3-ketoacyl-CoA synthase 10 [KO:K15397] [EC:2.3.1.199]
106760153  3-ketoacyl-CoA synthase 1 [KO:K15397] [EC:2.3.1.199]
106772416  3-ketoacyl-CoA synthase 11 [KO:K15397] [EC:2.3.1.199]
106769152  3-ketoacyl-CoA synthase 11 isoform X2 [KO:K15397] [EC:2.3.1.199]
106774992  3-ketoacyl-CoA synthase 7 [KO:K15397] [EC:2.3.1.199]
106776380  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
106775630  3-ketoacyl-CoA synthase 15 [KO:K15397] [EC:2.3.1.199]
106765300  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
106772353  3-ketoacyl-CoA synthase 6 [KO:K15397] [EC:2.3.1.199]
106760038  probable 3-ketoacyl-CoA synthase 21 [KO:K15397] [EC:2.3.1.199]
106763681  3-ketoacyl-CoA synthase 20 [KO:K15397] [EC:2.3.1.199]
106772491  3-ketoacyl-CoA synthase 19-like [KO:K15397] [EC:2.3.1.199]
106762352  3-ketoacyl-CoA synthase 4 [KO:K15397] [EC:2.3.1.199]
106770661  3-ketoacyl-CoA synthase 6-like [KO:K15397] [EC:2.3.1.199]
106769687  3-ketoacyl-CoA synthase 19 [KO:K15397] [EC:2.3.1.199]
106764762  WRKY transcription factor 1 [KO:K18834]
106762449  probable WRKY transcription factor 2 [KO:K18835]
106759467  probable WRKY transcription factor 33 isoform X1 [KO:K18835]
106768898  lysM domain receptor-like kinase 3 isoform X2 [KO:K13429]
106774891  chitin elicitor receptor kinase 1 isoform X1 [KO:K13429]
Compound
C00027  Hydrogen peroxide
C00076  Calcium cation
C00533  Nitric oxide
C00704  Superoxide
C16844  Hydroxyl radical
Reference
PMID:18206360
  Authors
Zipfel C
  Title
Pattern-recognition receptors in plant innate immunity.
  Journal
Curr Opin Immunol 20:10-6 (2008)
DOI:10.1016/j.coi.2007.11.003
Reference
PMID:19748302
  Authors
Chinchilla D, Shan L, He P, de Vries S, Kemmerling B
  Title
One for all: the receptor-associated kinase BAK1.
  Journal
Trends Plant Sci 14:535-41 (2009)
DOI:10.1016/j.tplants.2009.08.002
Reference
PMID:19423812
  Authors
Boller T, He SY
  Title
Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens.
  Journal
Science 324:742-4 (2009)
DOI:10.1126/science.1171647
Reference
PMID:19794842
  Authors
Ma W, Smigel A, Verma R, Berkowitz GA
  Title
Cyclic nucleotide gated channels and related signaling components in plant innate immunity.
  Journal
Plant Signal Behav 4:277-82 (2009)
DOI:10.4161/psb.4.4.8103
Reference
PMID:11875555
  Authors
Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J
  Title
MAP kinase signalling cascade in Arabidopsis innate immunity.
  Journal
Nature 415:977-83 (2002)
DOI:10.1038/415977a
Reference
PMID:15922649
  Authors
Zipfel C, Felix G
  Title
Plants and animals: a different taste for microbes?
  Journal
Curr Opin Plant Biol 8:353-60 (2005)
DOI:10.1016/j.pbi.2005.05.004
Reference
PMID:17451411
  Authors
He P, Shan L, Sheen J
  Title
Elicitation and suppression of microbe-associated molecular pattern-triggered immunity in plant-microbe interactions.
  Journal
Cell Microbiol 9:1385-96 (2007)
DOI:10.1111/j.1462-5822.2007.00944.x
Reference
PMID:17876517
  Authors
de Wit PJ
  Title
How plants recognize pathogens and defend themselves.
  Journal
Cell Mol Life Sci 64:2726-32 (2007)
DOI:10.1007/s00018-007-7284-7
Reference
PMID:16497589
  Authors
Chisholm ST, Coaker G, Day B, Staskawicz BJ
  Title
Host-microbe interactions: shaping the evolution of the plant immune response.
  Journal
Cell 124:803-14 (2006)
DOI:10.1016/j.cell.2006.02.008
Reference
PMID:16677430
  Authors
McHale L, Tan X, Koehl P, Michelmore RW
  Title
Plant NBS-LRR proteins: adaptable guards.
  Journal
Genome Biol 7:212 (2006)
DOI:10.1186/gb-2006-7-4-212
Reference
PMID:11459065
  Authors
Dangl JL, Jones JD
  Title
Plant pathogens and integrated defence responses to infection.
  Journal
Nature 411:826-33 (2001)
DOI:10.1038/35081161
Reference
PMID:17108957
  Authors
Jones JD, Dangl JL
  Title
The plant immune system.
  Journal
Nature 444:323-9 (2006)
DOI:10.1038/nature05286
Reference
PMID:16697674
  Authors
da Cunha L, McFall AJ, Mackey D
  Title
Innate immunity in plants: a continuum of layered defenses.
  Journal
Microbes Infect 8:1372-81 (2006)
DOI:10.1016/j.micinf.2005.12.018
Reference
PMID:15862106
  Authors
Mudgett MB
  Title
New insights to the function of phytopathogenic bacterial type III effectors in plants.
  Journal
Annu Rev Plant Biol 56:509-31 (2005)
DOI:10.1146/annurev.arplant.56.032604.144218
Reference
PMID:17714518
  Authors
Ma W, Berkowitz GA
  Title
The grateful dead: calcium and cell death in plant innate immunity.
  Journal
Cell Microbiol 9:2571-85 (2007)
DOI:10.1111/j.1462-5822.2007.01031.x
Reference
PMID:14711430
  Authors
Schulze-Lefert P
  Title
Plant immunity: the origami of receptor activation.
  Journal
Curr Biol 14:R22-4 (2004)
DOI:10.1016/j.cub.2003.12.017
Reference
PMID:9868361
  Authors
Van der Biezen EA, Jones JD
  Title
Plant disease-resistance proteins and the gene-for-gene concept.
  Journal
Trends Biochem Sci 23:454-6 (1998)
DOI:10.1016/S0968-0004(98)01311-5
Reference
PMID:16936700
  Authors
Abramovitch RB, Anderson JC, Martin GB
  Title
Bacterial elicitation and evasion of plant innate immunity.
  Journal
Nat Rev Mol Cell Biol 7:601-11 (2006)
DOI:10.1038/nrm1984
Related
pathway
vra04144  Endocytosis
KO pathway
ko04626   
LinkDB

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