Entry Name ABC transporters - Xenorhabdus doucetiae
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Xenorhabdus doucetiae [GN:
xdo ]
Gene XDD1_1366 modB; Molybdenum transport system permease protein modB [KO:K02018 ]
XDD1_1362 modF; putative molybdenum transport ATP-binding protein ModF [KO:K05776 ]
XDD1_3376 thiP; Thiamine transport system permease protein thiP [KO:K02063 ]
XDD1_0693 potD; Spermidine/putrescine-binding periplasmic protein [KO:K11069 ]
XDD1_0694 potC; Spermidine/putrescine transport system permease protein potC [KO:K11070 ]
XDD1_0695 potB; Spermidine/putrescine transport system permease protein potB [KO:K11071 ]
XDD1_1255 proW; Glycine betaine/L-proline transport system permease protein proW [KO:K02001 ]
XDD1_3636 malK; Maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
XDD1_3519 mlaD; putative phospholipid ABC transporter-binding protein mlaD [KO:K02067 ]
XDD1_3520 mlaE; putative phospholipid ABC transporter permease protein mlaE [KO:K02066 ]
XDD1_3521 mlaF; putative phospholipid import ATP-binding protein mlaF [KO:K02065 ]
XDD1_3855 pstC; Phosphate transport system permease protein pstC [KO:K02037 ]
XDD1_3854 pstA; Phosphate transport system permease protein pstA [KO:K02038 ]
XDD1_1542 artI; putative ABC transporter arginine-binding protein 2 [KO:K09997 ]
XDD1_1281 gltI; Glutamate/aspartate periplasmic-binding protein [KO:K10001 ]
XDD1_1279 gltK; Glutamate/aspartate transport system permease protein gltK [KO:K10002 ]
XDD1_1280 gltJ; Glutamate/aspartate transport system permease protein gltJ [KO:K10003 ]
XDD1_0519 putative amino-acid ABC transporter-binding protein HI_1080 [KO:K02424 ]
XDD1_0520 tcyB; L-cystine transport system permease protein tcyB [KO:K10009 ]
XDD1_3279 metI; D-methionine transport system permease protein metI [KO:K02072 ]
XDD1_0815 oppA; OppA-like, oligopeptide transport protein (ABC superfamily, peri_bind) [KO:K15580 ]
XDD1_0816 oppA; oligopeptide transport protein (ABC superfamily, peri_bind) [KO:K15580 ]
XDD1_2234 oppA; oligopeptide transport protein (ABC superfamily, peri_bind) [KO:K15580 ]
XDD1_2235 oppA; oligopeptide transport protein (ABC superfamily, peri_bind) [KO:K15580 ]
XDD1_2233 oppB; oligopeptide transport protein (ABC superfamily, membrane) [KO:K15581 ]
XDD1_2232 oppC; oligopeptide transport protein (ABC superfamily, membrane) [KO:K15582 ]
XDD1_2231 oppD; oligopeptide transport protein (ABC superfamily, atp_bind) [KO:K15583 ]
XDD1_2230 oppF; oligopeptide transport protein (ABC superfamily, atp_bind) [KO:K10823 ]
XDD1_3779 dppB; Dipeptide transport system permease protein dppB [KO:K12369 ]
XDD1_3778 dppC; Dipeptide transport system permease protein dppC [KO:K12370 ]
XDD1_1871 sapD; Peptide transport system ATP-binding protein sapD [KO:K19229 ]
XDD1_1870 sapF; Peptide transport system ATP-binding protein sapF [KO:K19230 ]
XDD1_1239 fepD; ferric enterobactin transport protein (ABC superfamily, membrane) [KO:K23186 ]
XDD1_1240 Ferric enterobactin transport system permease protein FepG [KO:K23187 ]
XDD1_1241 fepC; ferric enterobactin transport protein (ABC superfamily, atp_bind) [KO:K23188 ] [EC:7.2.2.17 7.2.2.-]
XDD1_2069 znuB; High-affinity zinc uptake system membrane protein znuB [KO:K09816 ]
XDD1_1760 Periplasmic chelated iron-binding protein yfeA precursor [KO:K11604 ]
XDD1_3687 lsrC; Autoinducer 2 import system permease protein lsrC [KO:K10556 ]
XDD1_3688 lsrD; Autoinducer 2 import system permease protein lsrD [KO:K10557 ]
XDD1_2485 lolE; Lipoprotein-releasing system transmembrane protein lolE [KO:K09808 ]
XDD1_2487 lolC; Lipoprotein-releasing system transmembrane protein lolC [KO:K09808 ]
XDD1_2486 lolD; Lipoprotein-releasing system ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
XDD1_0664 lptF; Lipopolysaccharide export system permease protein lptF [KO:K07091 ]
XDD1_0663 lptG; Lipopolysaccharide export system permease protein lptG [KO:K11720 ]
XDD1_0887 mdlA; Multidrug resistance-like ATP-binding protein MdlA [KO:K18889 ]
XDD1_0888 mdlB; Multidrug resistance-like ATP-binding protein MdlB [KO:K18890 ]
XDD1_3326 aprD; Alkaline protease secretion ATP-binding protein AprD [KO:K12536 ]
XDD1_1547 macB; Macrolide export ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
