KEGG   PATHWAY: ypb00740
Entry
ypb00740                    Pathway                                
Name
Riboflavin metabolism - Yersinia pseudotuberculosis PB1/+ (serotype 1B)
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
ypb00740  Riboflavin metabolism
ypb00740

Module
ypb_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:ypb00740]
Other DBs
GO: 0006771
Organism
Yersinia pseudotuberculosis PB1/+ (serotype 1B) [GN:ypb]
Gene
YPTS_2214  GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
YPTS_0975  riboflavin biosynthesis protein RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
YPTS_0206  HAD-superfamily hydrolase, subfamily IA, variant 1 [KO:K20862] [EC:3.1.3.102 3.1.3.104]
YPTS_3546  3,4-dihydroxy-2-butanone 4-phosphate synthase [KO:K02858] [EC:4.1.99.12]
YPTS_0976  6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
YPTS_2378  riboflavin synthase, alpha subunit [KO:K00793] [EC:2.5.1.9]
YPTS_0640  riboflavin biosynthesis protein RibF [KO:K11753] [EC:2.7.1.26 2.7.7.2]
YPTS_2503  histidine acid phosphatase [KO:K01093] [EC:3.1.3.26 3.1.3.2]
YPTS_1770  4-hydroxyphenylacetate 3-monooxygenase, reductase subunit [KO:K00484] [EC:1.5.1.36]
YPTS_0281  oxidoreductase FAD/NAD(P)-binding domain protein [KO:K05368] [EC:1.5.1.41]
YPTS_3796  NADPH-dependent FMN reductase [KO:K00299] [EC:1.5.1.38]
YPTS_3540  NUDIX hydrolase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
YPTS_2512  NUDIX hydrolase [KO:K12152] [EC:3.6.1.-]
YPTS_2706  3-octaprenyl-4-hydroxybenzoate carboxy-lyase [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
ypb00030  Pentose phosphate pathway
ypb00040  Pentose and glucuronate interconversions
ypb00230  Purine metabolism
ypb00860  Porphyrin metabolism
ypb00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

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