Petaurus breviceps papuanus (sugar glider): 138176513
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Entry
138176513 CDS
T10505
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
pbrv Petaurus breviceps papuanus (sugar glider)
Pathway
pbrv00350
Tyrosine metabolism
pbrv00790
Folate biosynthesis
pbrv01100
Metabolic pathways
pbrv04728
Dopaminergic synapse
pbrv04917
Prolactin signaling pathway
pbrv05012
Parkinson disease
pbrv05030
Cocaine addiction
pbrv05031
Amphetamine addiction
pbrv05034
Alcoholism
Module
pbrv_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
pbrv00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
138176513 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
138176513 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
138176513 (TH)
09156 Nervous system
04728 Dopaminergic synapse
138176513 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
138176513 (TH)
09165 Substance dependence
05030 Cocaine addiction
138176513 (TH)
05031 Amphetamine addiction
138176513 (TH)
05034 Alcoholism
138176513 (TH)
Enzymes [BR:
pbrv01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
138176513 (TH)
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Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
138176513
NCBI-ProteinID:
XP_068963398
LinkDB
All DBs
Position
Unknown
AA seq
498 aa
AA seq
DB search
MPMPNTSTPPAKGFRRAVSELDSKQAEAIMVRAASPRFIGRRQSLIEDARKEREAAVAAA
AAEASGDPLDTIVFEEKDGKALLNLFFTLKTAKSTSLSRALKVFETFEAKIHHLETRASR
KPREGTSELEYFVRCEVHSGDLNTLLSSVRRVSDEVRSTKEDKIHWFPRKISELDKCHHL
VTKFDPDLDLDHPGFSDQVYRQRRKAIAEIAFQYKQGEPIPRVEYTAEEIATWREVYSTL
KSLYPTHACREHLEAFQLLERFCGYSENSIPQLEDVSRFLKERTGFQLRPVAGLLSARDF
LSSLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGAT
DEEIEKLSTLYWFTVEFGLCKQNGAVKAYGAGLLSSYGELLHSLSEEPEVREFDPDAAAV
QPYQDQTYQPVYFVSESFSDAKDKLRSYSTRIRRPFSVKFDPYTLGIEVLDSPQKIRHSL
QGVQDELHLLAHALNALS
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atgcccatgccgaacacctccacacctccagccaagggcttccgcagggcagtgtccgag
ctggattccaaacaggcagaggccattatggtaagggctgcatccccaaggttcattggc
aggcggcagagcctcattgaagatgcccgcaaagaaagagaggcagccgtggcggcagca
gcagcagaggcctccggggaccccctggacaccatcgtctttgaggagaaggatgggaag
gcccttctcaacctcttcttcaccctaaagacagccaaatcaacatcattgtcccgggcc
ctgaaagtgttcgagacgttcgaagccaaaatccatcacctggagacgagggccagcaga
aagccgagggaagggacctcggagctcgagtacttcgtccgctgtgaagtccacagcggc
gacctgaacaccttgctcagctcggtccggagggtctccgatgaggtgcgcagcaccaag
gaagacaagattcactggtttcccagaaagatctctgagctggataaatgccaccacctg
gtcaccaagtttgaccctgaccttgacctggatcaccctggattttctgaccaggtctat
cgccagaggaggaaggcaatagcagaaatcgctttccaatataagcagggagagccgata
ccccgtgtggagtacacagcagaggagatcgccacctggagagaggtctacagcaccctg
aaaagcctgtatcccacccatgcatgccgggagcacctggaagccttccagctgctggaa
aggttctgtggctacagcgagaacagcattccccagctggaagatgtttcccgctttcta
aaggagaggacagggttccagctgcggccggtggccggcctgctctctgcccgggacttc
ctgtccagcctggccttcagggtgttccaatgcactcaatacatccgccatgcctcctcg
cccatgcactccccagagccggactgctgtcatgaactcctggggcacgtgcccatgctg
gcagacaggacttttgcccagttctcccaggacatcggccttgcctcccttggtgctact
gatgaggaaattgagaagttatccacgctctactggttcactgtggaattcgggctctgc
aaacagaatggagctgtgaaagcctatggtgccggccttctgtcctcctacggggagctg
cttcactccctgtccgaggagcccgaggtccgggagtttgacccggatgctgccgctgtg
cagccgtaccaggaccaaacctaccagcccgtctactttgtatcagagagcttcagtgat
gccaaggacaagctccggagctactcaactcgaatccgccgccccttctctgtgaagttc
gacccctacacgctgggcatcgaggtcctggacagcccccagaaaatccggcactccctg
caaggagtccaggatgagcttcacctgttggcccacgccctcaatgccctgagctaa
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