Physeter macrocephalus (sperm whale): 102996827 Help Entry 102996827         CDS       T06011                                  Symbol TH Name (RefSeq) tyrosine 3-monooxygenase   KO K00501   tyrosine 3-monooxygenase [EC:1.14.16.2] Organism pcad  Physeter macrocephalus (sperm whale) Pathway pcad00350   Tyrosine metabolism pcad00790   Folate biosynthesis pcad01100   Metabolic pathways pcad04728   Dopaminergic synapse pcad04917   Prolactin signaling pathway pcad05012   Parkinson disease pcad05030   Cocaine addiction pcad05031   Amphetamine addiction pcad05034   Alcoholism Module pcad_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Brite KEGG Orthology (KO) [BR:pcad00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     102996827 (TH)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     102996827 (TH)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     102996827 (TH)   09156 Nervous system    04728 Dopaminergic synapse     102996827 (TH)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     102996827 (TH)   09165 Substance dependence    05030 Cocaine addiction     102996827 (TH)    05031 Amphetamine addiction     102996827 (TH)    05034 Alcoholism     102996827 (TH) Enzymes [BR:pcad01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.2  tyrosine 3-monooxygenase      102996827 (TH) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Biopterin_H TH_ACT TOH_N LTP_2 Motif Other DBs NCBI-GeneID:  102996827 NCBI-ProteinID:  XP_023973341 Ensembl:  ENSPCTG00005008078 UniProt:  A0A2Y9S422 LinkDB All DBs Position 18:3105942..3112964 Genome browser AA seq 489 aa AA seqDB search MPTPNAASPPAKGFRRAVSELDAKQAEAIMSPHFVGRRQSLIQDARKEREKAEAAAAAAE PGEAPEERDGTAVRNLLFTLRATKPPALSRAVKVFETFEAQIHHLETRPAQKPRAGGPHL EYFVRCEVPSAALPTLLSSLRRVAEDVRGAGENKVLWFPRKVSELDKCHHLVTKFDPDLD LDHPGFSDQLYRQRRKLIAEIAFQYKQGDPIPHVEYTAEETATWKEVYTTLRGLYATHAC REHLEAFELLERFCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVF QCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEDIEKLST LYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEGPEIRAFDPDAAAVQPYQDQTYQ PVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDGPHAIRRALDGVRDELYT LTRALSAIS NT seq 1470 nt NT seq  +upstreamnt  +downstreamnt atgcccacccctaacgctgcctcgccgccggccaagggcttccgcagggccgtctccgag ctggacgccaagcaggccgaggccatcatgtccccgcacttcgtcgggaggcggcagagc ctcatccaggacgcccgcaaggagagagagaaggcggaggccgcagccgcagccgcggag ccgggcgaggccccggaggagcgggacgggacggccgtgcggaatctcctcttcaccctg cgcgccaccaagccccccgcgctgtcccgggccgtgaaggtgtttgagacatttgaagcc caaatccaccacctggagacccggccggcccagaagccgcgggcagggggcccgcacctg gagtacttcgtgcgctgtgaggtacccagcgccgccctgcccacccttctcagctccctt cgccgcgtggccgaagacgtgcggggcgccggggagaacaaggtcctctggttcccaagg aaagtttctgagctggacaagtgtcaccacctggtcaccaagtttgaccctgacctggac ttggaccatccgggcttctcggaccagctgtaccgccagcgcaggaagctgattgctgag atcgccttccagtacaagcaaggcgaccctattccccacgtggagtacacggccgaggag accgccacctggaaggaggtctacaccacgctgcggggcctctacgccacccacgcgtgc cgggaacacctggaggctttcgagctgctggagcgcttctgcgggtaccgggaggacagc atcccccagctggaggacgtctcccgcttcctgaaggagcggaccggcttccagctgcgg cccgtggccggcctgctgtccgcccgggacttcctggccagcctggccttccgcgtgttc cagtgcacccagtacatccgccatgcctcctcacccatgcactcccccgagccggactgc tgccacgagctgctggggcacgtgcccatgctggccgaccggaccttcgcccagttctcc caggacatcggcctcgcatccctgggggcatcggacgaagacattgagaagctgtccacg ctgtactggttcaccgtggagtttgggctgtgcaaacagaacggcgagctgaaggcctac ggagcggggctgctgtcctcctacggggagctcctgcactccctgtctgaggggcccgag atccgggccttcgaccccgacgcagcggccgtgcagccctaccaggaccagacttatcag cctgtctacttcgtgtctgagagtttcagcgacgccaaggacaagctcaggagctatgcc tcccgcatccagcgccccttctccgtgaagttcgacccgtacacgctggccatcgatgtg ctggacggtccccacgccatccgacgcgccctggatggtgtccgggacgagctgtacacc ctcacccgcgccctgagcgccatcagctag

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