Puma concolor (puma): 112870035 Help Entry 112870035         CDS       T08890                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X1   KO K02187   caspase 3 [EC:3.4.22.56] Organism pcoo  Puma concolor (puma) Pathway pcoo01524   Platinum drug resistance pcoo04010   MAPK signaling pathway pcoo04115   p53 signaling pathway pcoo04148   Efferocytosis pcoo04210   Apoptosis pcoo04215   Apoptosis - multiple species pcoo04623   Cytosolic DNA-sensing pathway pcoo04650   Natural killer cell mediated cytotoxicity pcoo04657   IL-17 signaling pathway pcoo04668   TNF signaling pathway pcoo04726   Serotonergic synapse pcoo04932   Non-alcoholic fatty liver disease pcoo04933   AGE-RAGE signaling pathway in diabetic complications pcoo04936   Alcoholic liver disease pcoo05010   Alzheimer disease pcoo05012   Parkinson disease pcoo05014   Amyotrophic lateral sclerosis pcoo05016   Huntington disease pcoo05020   Prion disease pcoo05022   Pathways of neurodegeneration - multiple diseases pcoo05132   Salmonella infection pcoo05133   Pertussis pcoo05134   Legionellosis pcoo05145   Toxoplasmosis pcoo05146   Amoebiasis pcoo05152   Tuberculosis pcoo05160   Hepatitis C pcoo05161   Hepatitis B pcoo05162   Measles pcoo05163   Human cytomegalovirus infection pcoo05164   Influenza A pcoo05165   Human papillomavirus infection pcoo05167   Kaposi sarcoma-associated herpesvirus infection pcoo05168   Herpes simplex virus 1 infection pcoo05169   Epstein-Barr virus infection pcoo05170   Human immunodeficiency virus 1 infection pcoo05200   Pathways in cancer pcoo05203   Viral carcinogenesis pcoo05205   Proteoglycans in cancer pcoo05206   MicroRNAs in cancer pcoo05210   Colorectal cancer pcoo05222   Small cell lung cancer pcoo05416   Viral myocarditis pcoo05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pcoo00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     112870035 (CASP3)    04668 TNF signaling pathway     112870035 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     112870035 (CASP3)   09143 Cell growth and death    04210 Apoptosis     112870035 (CASP3)    04215 Apoptosis - multiple species     112870035 (CASP3)    04115 p53 signaling pathway     112870035 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     112870035 (CASP3)    04650 Natural killer cell mediated cytotoxicity     112870035 (CASP3)    04657 IL-17 signaling pathway     112870035 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     112870035 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     112870035 (CASP3)    05206 MicroRNAs in cancer     112870035 (CASP3)    05205 Proteoglycans in cancer     112870035 (CASP3)    05203 Viral carcinogenesis     112870035 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     112870035 (CASP3)    05222 Small cell lung cancer     112870035 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     112870035 (CASP3)    05161 Hepatitis B     112870035 (CASP3)    05160 Hepatitis C     112870035 (CASP3)    05164 Influenza A     112870035 (CASP3)    05162 Measles     112870035 (CASP3)    05168 Herpes simplex virus 1 infection     112870035 (CASP3)    05163 Human cytomegalovirus infection     112870035 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     112870035 (CASP3)    05169 Epstein-Barr virus infection     112870035 (CASP3)    05165 Human papillomavirus infection     112870035 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     112870035 (CASP3)    05133 Pertussis     112870035 (CASP3)    05134 Legionellosis     112870035 (CASP3)    05152 Tuberculosis     112870035 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     112870035 (CASP3)    05145 Toxoplasmosis     112870035 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     112870035 (CASP3)    05012 Parkinson disease     112870035 (CASP3)    05014 Amyotrophic lateral sclerosis     112870035 (CASP3)    05016 Huntington disease     112870035 (CASP3)    05020 Prion disease     112870035 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     112870035 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     112870035 (CASP3)    05416 Viral myocarditis     112870035 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     112870035 (CASP3)    04932 Non-alcoholic fatty liver disease     112870035 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     112870035 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     112870035 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pcoo01002]     112870035 (CASP3) Enzymes [BR:pcoo01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      112870035 (CASP3) Peptidases and inhibitors [BR:pcoo01002]  Cysteine peptidases   Family C14: caspase family    112870035 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  112870035 NCBI-ProteinID:  XP_025788896 UniProt:  A0A6P6IKZ1 LinkDB All DBs Position Unknown AA seq 277 aa AA seqDB search MENSENSVDAKSIKNSETKIFHGSKSMDSGIYMDNSYKMDYPEMGLCIIINNKNFHESTG MPSRSGTDVDAANLRETFTNLKYEVRNKNDLTREQIVALLDSVSREDHSKRSSFICVLLS HGDEGIIYGTNGPVDLKKLTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTED DIACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLKLYAHKLEFMHILTRVN RKVALEFESFSLDSAFHGKKQIPCIVSMLTKELYFYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacagtgaaaactcagtggatgcaaaatccattaaaaattccgaaacaaagatc ttccatggaagcaaatcaatggactctggaatatacatggacaacagttacaaaatggat taccctgaaatgggtttatgtataataattaataataagaactttcatgaaagtaccgga atgccatctcggtctggtacagatgtggatgcggcgaacctccgagaaacattcacaaac ttgaaatacgaagtcaggaataaaaacgatcttacacgcgaacaaattgtggcgttgctg gacagtgtttctagagaagatcatagcaaaaggagcagttttatttgcgtgcttctaagc cacggtgatgaaggaatcatttatggaacaaacggacctgttgacctgaaaaaattaaca ggtttcttcagaggggattattgtagaagtctaaccggcaaacccaaactcttcattatt caggcctgccgaggcacggaactcgactgcggcattgagactgacagtggtaccgaggat gacatcgcctgtcagaaaataccagtggaagccgacttcttatatgcgtattccacagcc cctggttactactcctggcgaaattccaaggatggatcctggttcatccagtcactttgc tcgatgctcaaactgtatgctcacaagcttgagttcatgcacattcttactcgggttaac cgaaaggtagctctagaatttgagtccttttctcttgactctgcttttcatggaaagaaa cagattccatgtattgtgtctatgctcacaaaagaactatatttttatcactaa

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