Propithecus coquereli (Coquerel's sifaka): 105816522
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Entry
105816522 CDS
T08746
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq00350
Tyrosine metabolism
pcoq00790
Folate biosynthesis
pcoq01100
Metabolic pathways
pcoq04728
Dopaminergic synapse
pcoq04917
Prolactin signaling pathway
pcoq05012
Parkinson disease
pcoq05030
Cocaine addiction
pcoq05031
Amphetamine addiction
pcoq05034
Alcoholism
Module
pcoq_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
105816522 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
105816522 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
105816522 (TH)
09156 Nervous system
04728 Dopaminergic synapse
105816522 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
105816522 (TH)
09165 Substance dependence
05030 Cocaine addiction
105816522 (TH)
05031 Amphetamine addiction
105816522 (TH)
05034 Alcoholism
105816522 (TH)
Enzymes [BR:
pcoq01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
105816522 (TH)
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Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
105816522
NCBI-ProteinID:
XP_012507407
Ensembl:
ENSPCOG00000024538
LinkDB
All DBs
Position
Unknown
AA seq
538 aa
AA seq
DB search
MMPTPSAATPQPKGFRRAVSELDAKQAEAIMVRGRTPPPDVPSPGDPGPCLTGSPWPGSS
ALAMSTPPSPQSPRFVGRRQSLIEDARKEREAAVAAAAAAASSEPGDPLEAVVFEEKAGK
AVLNLLFSLGGTKPSALSQALKVFETFEAKIHHLETRPTQRPRAGGPQLEYFVRCELPRR
DLAALLSSVRRVSEDVRSAREDKVPWFPRKASELDKCHHLVTKFDPDLDLDHPGFSDQVY
RQRRKLIADIAFQYKHGSPIPCVEYTAEETATWKEVYTTLKGLYATHACREYLQAFQLLE
RFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASS
PMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLC
KQNGELKAYGAGLLSSYGELLHSLSEEPEIRAFDPEAAAVQPYQDQTYQSVYFVSESFSD
AKDKLRSYASRIQRPFSVKFDPYTRAVDVLDSPRAVLRSLEGVQDELHTLAHALSAIS
NT seq
1617 nt
NT seq
+upstream
nt +downstream
nt
atgatgcccacccccagcgctgccacgccgcagcccaagggcttccgcagggccgtctct
gagctggacgccaagcaggcggaggccatcatggtaagagggcgcacgccaccccccgac
gtcccctccccaggggacccggggccctgccttaccggctctccctggcctgggtcttca
gccttggccatgtccacacccccgtccccacagtccccgcggttcgtcgggcggcggcag
agcctcatcgaggacgcccgcaaggagagggaggcggcggtggctgcggcggccgcggcg
gcctcctcggagcccggggaccccctggaggccgtggtgttcgaggagaaggcggggaag
gctgtgctgaacttgctcttctccctggggggcaccaagccctcggcactgtcccaggcc
ctgaaggtgttcgagacgtttgaagccaaaatccaccacctggagacccggcccactcag
aggccccgggccgggggcccgcagctggagtacttcgtgcgctgcgagctgccccgcagg
gacctggccgccctgctcagttctgtgcgccgggtgtccgaggacgtgcgcagcgccagg
gaggacaaggtcccctggttcccaagaaaagcgtcggagctggacaaatgtcaccacctg
gtcaccaagtttgatcctgacctggacttggaccacccgggcttctcggaccaggtgtac
cgccagcgcaggaagctcattgccgacattgccttccagtacaagcacggcagcccgatt
ccctgtgtggagtacaccgcggaggagactgccacctggaaggaggtctacaccacgctg
aaggggctgtacgccacgcacgcctgccgggagtacctgcaggccttccagctgctggag
cgcttcagcggctaccgcgaggacagcatcccccagctggaggacgtctcccgcttcctg
aaggagcggacgggcttccagctgcggcccgtggccggcctgctgtctgcccgcgacttc
ctggccagcctggccttccgcgtgttccagtgcacccagtacatccgccacgcgtcctcg
cccatgcactcccccgagccggactgctgccacgagctgctggggcacgtgcccatgctg
gccgaccgcaccttcgcccagttctcccaggacattggccttgcctccctgggggcctcg
gacgaggagattgagaagctgtccacgctgtactggttcacggtggagtttggtctctgc
aaacagaacggggagctgaaggcctatggcgccgggctgctgtcctcctacggggagctc
ctgcactccctgtctgaggagcccgagatccgggccttcgaccccgaggctgcggccgtg
cagccctaccaagaccagacctaccagtccgtctacttcgtgtctgagagtttcagcgac
gccaaggacaagctcaggagctacgcctcgcgaatccagcgccccttctctgtgaagttc
gacccctacacgcgggccgtcgacgtgctggacagcccccgcgccgtcctgcgctccctg
gagggcgtccaggacgagctgcacaccctcgcccacgcgctcagcgccatcagctag
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