Phascolarctos cinereus (koala): 110212614
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Entry
110212614 CDS
T05867
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X1
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
pcw
Phascolarctos cinereus (koala)
Pathway
pcw04148
Efferocytosis
pcw04330
Notch signaling pathway
pcw04668
TNF signaling pathway
pcw05010
Alzheimer disease
pcw05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pcw00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
110212614 (ADAM17)
04668 TNF signaling pathway
110212614 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
110212614 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
110212614 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
110212614 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
pcw01002
]
110212614 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pcw04090
]
110212614 (ADAM17)
Enzymes [BR:
pcw01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
110212614 (ADAM17)
Peptidases and inhibitors [BR:
pcw01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
110212614 (ADAM17)
CD molecules [BR:
pcw04090
]
Proteins
110212614 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Reprolysin_5
Reprolysin_2
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
110212614
NCBI-ProteinID:
XP_020848276
UniProt:
A0A6P5KXT5
LinkDB
All DBs
Position
Unknown
AA seq
824 aa
AA seq
DB search
MKLCILVLLLWFPVLLAWRPPDEPGYDSHPPNEKLDSMLSDYDILSLSNIQQHSLRKRDL
QTASHLERLLTFSALHRHFKVYLTSSAERFSQNFKVLVVDGKEEQEYPVKWQDFFTGHVV
GEHNSRVLAHIGDDDFTVRINTDGAEYNIEPLWRFINDTQDKRMLVYKSEDIKNVSRFQS
PKVCGYLKIEKEELLPKGLEDTEQHTVHVHREKRAPPNPMKNTCKLLVVADHRFYKYMGR
GEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKTPQEVKPGEKHFNMA
KSYPNEEKDAWDVKMLLEQFSFDIAEDASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSH
GGVCPKAYYSSVGRKNIFLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLA
ECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIFKTIESKARECFQERNNNVCGNS
RVDEGEECDPGIMYLNNDTCCNTNCTLKKGVQCSDRNSPCCKNCQFETAEKKCQEAINAT
CKGVSYCTGNSSECPPPGNAADDTVCLDLGKCKDGECIPFCEREKNLQSCACNETDHSCK
VCCRDESGRCVPYLDADNNFLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSI
NTFGKFLADNIVGSVLVFSLILWIPLSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDS
ASVRIIKPFPVPQPPGRLQPLQPAPVMPSVAPKLDHQRMDTIQEDPSTDSILDEDAFEKD
PFPNSSSAAKSFEDLTDHPVTRSEKASSFKLQRQSRVDSKETEC
NT seq
2475 nt
NT seq
+upstream
nt +downstream
nt
atgaagttatgcatcctcgtcctcctcctctggttccctgtgctgctggcgtggagaccc
ccggacgagcctgggtacgactctcatcctccgaacgagaagcttgattccatgctatca
gactatgatatcctttctctgtcaaacatccagcaacattccttgaggaaaagggatcta
cagacagcatcacatttagaaagattattgactttttcagccttacataggcattttaag
gtatatctaacatcaagtgctgaacgcttttcacaaaatttcaaagtgttggtcgtggat
gggaaagaagagcaagaatatcctgtaaaatggcaagattttttcacggggcatgtagtg
ggtgaacacaattccagggttctggcccatataggtgatgatgactttacagtgagaatc
aatacagatggggcagaatataacatagagccactctggagatttattaatgatacccag
gacaagagaatgttggtttataaatctgaagatatcaagaatgtttcacgtttccaatct
ccaaaagtatgtggttatttgaagattgaaaaggaagaactgctccctaaaggactggaa
gacacggaacaacatacagtgcatgttcatcgggagaagagagctcctccaaatccaatg
aagaatacatgcaagttactggttgtagcagaccatcgtttttacaagtacatgggcaga
ggggaagagagcacaactacaaattacttaattgagctgattgacagagttgatgacatc
tatcggaatacatcctgggacaatgcaggttttaaaggttatggcatacagatagaacag
attcgtatcctcaagacacctcaagaggtaaaacctggtgaaaagcactttaacatggca
aaaagttatcccaatgaagagaaggatgcttgggatgtgaagatgttactagagcaattc
agctttgatatagctgaggatgcatcaaaagtttgccttgcacatcttttcacatatcaa
gattttgatatgggaactcttggattagcatatgttggatctcccagagcaaacagtcac
ggaggtgtttgtccaaaagcgtattatagctctgttgggagaaagaacatctttctgaac
agtggtttgaccagcacaaaaaattatggtaaaaccatccttacaaaggaagctgatttg
gttacaactcatgaactgggacacaactttggagcagaacatgatcctgacggcttagca
gaatgtgccccaaatgaagatcagggaggaaaatatgttatgtatccgatagctgtgagt
ggagaccatgagaataataagatgttttcaaactgcagtaaacaatccatcttcaagact
atcgaaagtaaggctcgggaatgttttcaagaacgcaacaacaatgtgtgtgggaattcc
agggtggatgaaggtgaagaatgtgatcctggcattatgtatctgaacaatgacacctgt
tgcaatacaaactgtaccttgaaaaaaggagttcagtgtagtgatagaaatagtccttgc
tgtaaaaattgtcagtttgagacagctgagaagaagtgccaggaggccatcaatgctacc
tgcaaaggcgtgtcctactgtacaggtaacagcagtgaatgtccccctcctggaaatgct
gcagatgatactgtttgcttggatttaggaaagtgtaaagatggagagtgtattcccttc
tgtgagagggagaagaatctccagtcttgtgcatgtaatgaaactgaccactcctgcaaa
gtatgctgtagggatgaatctggccgatgtgttccataccttgatgctgacaataacttc
ttatttttgaggaaaggaaagccctgtactgtgggattttgtgacatgaatggtaaatgt
gagaaacgagtgcaggatgtgatagagcgattttgggatttcattgatcagctgagcatc
aatacttttgggaagtttttagcagacaacattgttggttcagtcctcgtcttttccttg
attttgtggattcccctcagcattcttgtccattgtgtggacaagaaattggataaacag
tatgagtctttgtctttgtttcaccccagtaatgtggaaatgctgagtagcatggactca
gcatctgttcgcatcatcaaaccatttcctgtgcctcaaccccctggtagacttcagcca
cttcagcctgctccagtgatgccctcagtggctccaaagctggaccaccaaaggatggac
accattcaggaagacccgagcactgattcaatccttgatgaagacgcctttgagaaggat
cctttcccaaatagcagctcagctgcaaagtcttttgaggatcttacagaccatcctgtc
acaaggagtgaaaaggcatcctcttttaaattacaacgccaaagtcgtgtggacagcaaa
gaaacagagtgctag
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