KEGG   Phascolarctos cinereus (koala): 110222594
Entry
110222594         CDS       T05867                                 
Symbol
CASP3
Name
(RefSeq) caspase-3
  KO
K02187  caspase 3 [EC:3.4.22.56]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw01524  Platinum drug resistance
pcw04010  MAPK signaling pathway
pcw04115  p53 signaling pathway
pcw04148  Efferocytosis
pcw04210  Apoptosis
pcw04215  Apoptosis - multiple species
pcw04623  Cytosolic DNA-sensing pathway
pcw04650  Natural killer cell mediated cytotoxicity
pcw04657  IL-17 signaling pathway
pcw04668  TNF signaling pathway
pcw04726  Serotonergic synapse
pcw04932  Non-alcoholic fatty liver disease
pcw04933  AGE-RAGE signaling pathway in diabetic complications
pcw04936  Alcoholic liver disease
pcw05010  Alzheimer disease
pcw05012  Parkinson disease
pcw05014  Amyotrophic lateral sclerosis
pcw05016  Huntington disease
pcw05020  Prion disease
pcw05022  Pathways of neurodegeneration - multiple diseases
pcw05132  Salmonella infection
pcw05133  Pertussis
pcw05134  Legionellosis
pcw05145  Toxoplasmosis
pcw05146  Amoebiasis
pcw05152  Tuberculosis
pcw05160  Hepatitis C
pcw05161  Hepatitis B
pcw05162  Measles
pcw05163  Human cytomegalovirus infection
pcw05164  Influenza A
pcw05165  Human papillomavirus infection
pcw05167  Kaposi sarcoma-associated herpesvirus infection
pcw05168  Herpes simplex virus 1 infection
pcw05169  Epstein-Barr virus infection
pcw05170  Human immunodeficiency virus 1 infection
pcw05200  Pathways in cancer
pcw05203  Viral carcinogenesis
pcw05205  Proteoglycans in cancer
pcw05206  MicroRNAs in cancer
pcw05210  Colorectal cancer
pcw05222  Small cell lung cancer
pcw05416  Viral myocarditis
pcw05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110222594 (CASP3)
   04668 TNF signaling pathway
    110222594 (CASP3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    110222594 (CASP3)
  09143 Cell growth and death
   04210 Apoptosis
    110222594 (CASP3)
   04215 Apoptosis - multiple species
    110222594 (CASP3)
   04115 p53 signaling pathway
    110222594 (CASP3)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    110222594 (CASP3)
   04650 Natural killer cell mediated cytotoxicity
    110222594 (CASP3)
   04657 IL-17 signaling pathway
    110222594 (CASP3)
  09156 Nervous system
   04726 Serotonergic synapse
    110222594 (CASP3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110222594 (CASP3)
   05206 MicroRNAs in cancer
    110222594 (CASP3)
   05205 Proteoglycans in cancer
    110222594 (CASP3)
   05203 Viral carcinogenesis
    110222594 (CASP3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    110222594 (CASP3)
   05222 Small cell lung cancer
    110222594 (CASP3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110222594 (CASP3)
   05161 Hepatitis B
    110222594 (CASP3)
   05160 Hepatitis C
    110222594 (CASP3)
   05164 Influenza A
    110222594 (CASP3)
   05162 Measles
    110222594 (CASP3)
   05168 Herpes simplex virus 1 infection
    110222594 (CASP3)
   05163 Human cytomegalovirus infection
    110222594 (CASP3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110222594 (CASP3)
   05169 Epstein-Barr virus infection
    110222594 (CASP3)
   05165 Human papillomavirus infection
    110222594 (CASP3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    110222594 (CASP3)
   05133 Pertussis
    110222594 (CASP3)
   05134 Legionellosis
    110222594 (CASP3)
   05152 Tuberculosis
    110222594 (CASP3)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    110222594 (CASP3)
   05145 Toxoplasmosis
    110222594 (CASP3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    110222594 (CASP3)
   05012 Parkinson disease
    110222594 (CASP3)
   05014 Amyotrophic lateral sclerosis
    110222594 (CASP3)
   05016 Huntington disease
    110222594 (CASP3)
   05020 Prion disease
    110222594 (CASP3)
   05022 Pathways of neurodegeneration - multiple diseases
    110222594 (CASP3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110222594 (CASP3)
   05416 Viral myocarditis
    110222594 (CASP3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110222594 (CASP3)
   04932 Non-alcoholic fatty liver disease
    110222594 (CASP3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    110222594 (CASP3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    110222594 (CASP3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pcw01002]
    110222594 (CASP3)
Enzymes [BR:pcw01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.56  caspase-3
     110222594 (CASP3)
Peptidases and inhibitors [BR:pcw01002]
 Cysteine peptidases
  Family C14: caspase family
   110222594 (CASP3)
SSDB
Motif
Pfam: Peptidase_C14
Other DBs
NCBI-GeneID: 110222594
NCBI-ProteinID: XP_020863340
UniProt: A0A6P5M564
LinkDB
Position
Unknown
AA seq 276 aa
MANTEITVDSKPTKSSVLKILHGSKSAESGLSSDSYKMDYPEMGLCVIINNKNFHPNTGM
SFRSGTDVDAAHLRDTFKNLKYEVRNKNDLTCKEIIELMYNVSKEDHSQRSSFVCVILSH
GEEGIIFGTDGSVELKRLTCFFKGDKCRSLTGKPKLFIIQACRGTELDCGVETDSGTDDD
VTCQKIPIEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYAHKLEIMQILTRVNR
KVATEFESYSLDVNFHAKKQVPCIMSMLTKELYFFP
NT seq 831 nt   +upstreamnt  +downstreamnt
atggcaaatactgaaattacagtagattcaaaacctaccaaaagttcagtactaaagatc
ctccatggtagcaagtcagcagaatctggattgtcatcagacagctataaaatggattat
ccagaaatggggctatgtgtaataatcaataataaaaattttcacccaaatactggcatg
tcatttcgttctggtacagatgtagatgcagcacacctcagggatacattcaagaacttg
aaatatgaagtcaggaataaaaatgatctgacatgtaaagaaataattgaattaatgtac
aatgtttctaaagaagatcacagccaaaggagcagttttgtttgcgtgattctaagtcat
ggtgaagaaggaatcatctttgggacggatggatctgttgagctgaaaagattaacatgt
ttctttaaaggggataagtgtagaagtctgacaggaaagccaaagctttttattattcag
gcatgtagaggcacagagttggattgtggtgttgaaacagacagtggcactgatgatgat
gtaacatgccagaaaatacctattgaggcagacttcttatatgcatattctacagcccca
ggctactattcttggagaaattcaaaggatggttcgtggtttatccagtcactttgcgca
atgctgaaacagtatgctcacaagcttgagataatgcaaatccttaccagagtcaatcgg
aaggttgctacagagtttgaatcttattccttagatgttaacttccatgcaaagaagcag
gtgccatgtatcatgtccatgcttactaaggaactgtattttttcccctaa

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