KEGG   Plasmodium falciparum Dd2: PFDG_04158
Entry
PFDG_04158        CDS       T01051                                 
Name
(GenBank) hypothetical protein
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
pfd  Plasmodium falciparum Dd2
Pathway
pfd00240  Pyrimidine metabolism
pfd00670  One carbon pool by folate
pfd00790  Folate biosynthesis
pfd01100  Metabolic pathways
pfd01232  Nucleotide metabolism
pfd01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:pfd00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    PFDG_04158
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    PFDG_04158
   00670 One carbon pool by folate
    PFDG_04158
Enzymes [BR:pfd01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     PFDG_04158
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     PFDG_04158
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-ProteinID: KOB89073
UniProt: A0A0L7M8E2
LinkDB
AA seq 608 aa
MMEQVCDVFDIYAICACCKVESKNEGKKNEVFNNYTFRGLGNKGVLPWKCISLDMKYFRA
VTTYVNESKYEKLKYKRCKYLNKETVDNVNDMPNSKKLQNVVVMGRTNWESIPKKFKPLS
NRINVILSRTLKKEDFDEDVYIINKVEDLIVLLGKLNYYKCFIIGGSVVYQEFLEKKLIK
KIYFTRINSTYECDVFFPEINENEYQIISVSDVYTSNNTTLDFIIYKKTNNKMLNEQNCI
KGEEKNNDMPLKNDDKDTCHMKKLTEFYKNVDKYKINYENDDDDEEEDDFVYFNFNKEKE
EKNKNSIHPNDFQIYNSLKYKYHPEYQYLNIIYDIMMNGNKQSDRTGVGVLSKFGYIMKF
DLSQYFPLLTTKKLFLRGIIEELLWFIRGETNGNTLLNKNVRIWEANGTREFLDNRKLFH
REVNDLGPIYGFQWRHFGAEYTNMYDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVK
DLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQP
AQFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHE
KISMDMAA
NT seq 1827 nt   +upstreamnt  +downstreamnt
atgatggaacaagtctgcgacgttttcgatatttatgccatatgtgcatgttgtaaggtt
gaaagcaaaaatgaggggaaaaaaaatgaggtttttaataactacacatttagaggtcta
ggaaataaaggagtattaccatggaaatgtatttccctagatatgaaatattttcgtgca
gttacaacatatgtgaatgaatcaaaatatgaaaaattgaaatataagagatgtaaatat
ttaaacaaagaaactgtggataatgtaaatgatatgcctaattctaaaaaattacaaaat
gttgtagttatgggaagaacaaactgggaaagcattccaaaaaaatttaaacctttaagc
aataggataaatgttatattgtctagaaccttaaaaaaagaagattttgatgaagatgtt
tatatcattaacaaagttgaagatctaatagttttacttgggaaattaaattactataaa
tgttttattataggaggttccgttgtttatcaagaatttttagaaaagaaattaataaaa
aaaatatattttactagaataaatagtacatatgaatgtgatgtattttttccagaaata
aatgaaaatgagtatcaaattatttctgttagcgatgtatatactagtaacaatacaaca
ttggattttatcatttataagaaaacgaataataaaatgttaaatgaacaaaattgtata
aaaggagaagaaaaaaataatgatatgcctttaaagaatgatgacaaagatacatgtcat
atgaaaaaattaacagaattttacaaaaatgtagacaaatataaaattaattatgaaaat
gatgatgatgatgaagaagaagatgattttgtttattttaattttaataaagaaaaagaa
gagaaaaataaaaattctatacatccaaatgattttcaaatatataatagcttgaaatat
aaatatcatcctgaataccaatatttaaatattatttatgatattatgatgaatggaaat
aaacaaagtgatcgaacgggagtaggtgttttaagtaaattcggatatattatgaaattt
gatttaagtcaatatttcccattattaactacgaagaaattatttttaagaggaattatt
gaagaattgctttggtttattagaggagaaacaaatggtaatacgttgttaaataagaat
gtaaggatatgggaagctaatggtactagggaatttttagataatagaaaattatttcat
agagaagttaacgatttaggacctatttatggttttcaatggagacatttcggtgctgaa
tatacaaatatgtatgataattatgaaaataaaggagtggatcaattaaaaaatataata
aatttaattaaaaatgatcctacaagtagaagaattcttttgtgtgcatggaatgtaaaa
gatcttgaccaaatggcattacctccttgtcatattttatgtcagttttatgttttcgat
gggaaattatcatgtattatgtatcaaagatcatgtgatttagggctaggagtacctttt
aatattgcttcttattctatttttactcatatgattgcacaagtctgtaatttgcaacct
gcgcagttcatacacgttttaggaaatgcacatgtttataataatcacattgatagttta
aaaattcaacttaacagaataccctatccattcccaacacttaaattaaatccagatatt
aaaaatattgaagattttacaatttcggattttacaatacaaaattatgttcatcatgaa
aaaatttcaatggatatggctgcttaa

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