Plasmodium sp. gorilla clade G2: 39740250
Help
Entry
39740250 CDS
T10353
Symbol
PADL01_0416400
Name
(RefSeq) bifunctional dihydrofolate reductase-thymidylate synthase
KO
K13998
dihydrofolate reductase / thymidylate synthase [EC:
1.5.1.3
2.1.1.45
]
Organism
plag Plasmodium sp. gorilla clade G2
Pathway
plag00240
Pyrimidine metabolism
plag00670
One carbon pool by folate
plag00790
Folate biosynthesis
plag01100
Metabolic pathways
plag01232
Nucleotide metabolism
plag01240
Biosynthesis of cofactors
Module
plag_M00841
Tetrahydrofolate biosynthesis, mediated by PTPS, GTP => THF
plag_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
plag00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
39740250 (PADL01_0416400)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
39740250 (PADL01_0416400)
00670 One carbon pool by folate
39740250 (PADL01_0416400)
Enzymes [BR:
plag01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.3 dihydrofolate reductase
39740250 (PADL01_0416400)
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
39740250 (PADL01_0416400)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Thymidylat_synt
DHFR_1
Motif
Other DBs
NCBI-GeneID:
39740250
NCBI-ProteinID:
XP_028536797
PlasmoDB:
PADL01_0416400
UniProt:
A0A2P9BSA3
LinkDB
All DBs
Position
4:680072..681898
Genome browser
AA seq
608 aa
AA seq
DB search
MMEQVCDVFDIYAICACCKVENKNEVKKNEVFNNYTFRGLGNKGVLPWKCNSLDMKYFCA
VTTYVNESKYEKLKYKRCKYLNKETLNNAMDMPNSKKLQNVVVMGRTSWESIPKKFKPLS
NRINVILSRTLKKEDFDEDVYIINTVEDLIVLLGKLNYYKCFIIGGSVVYKEFLEKKLIK
KIYFTRINSSYECDVFFPEINENEYQIISVSDVYTCNNTTLDFVIYKKKNNQVLNEKDCI
EGEEKNNDMSLKNDDKDTCPMKKLTEFYKNVDKYKINYENDNDDDEEDDFVYFNFNKEKE
EKNKNCVHPNDFKIYNSLKHKCHPEYQYLNIIYDIIMNGNKQSDRTGVGVLSKFGYIMKF
DLSQYFPLLTTKKLFLRGIIEELLWFVRGETNGNTLLNKNVRIWEANGTREFLDNRKLFH
REVNDLGPIYGFQWRHFGAEYTNMHDNYENKGVDQLKNIINLIKNDPTSRRILLCAWNVK
DLDQMALPPCHILCQFYVFDGKLSCIMYQRSCDLGLGVPFNIASYSIFTHMIAQVCNLQP
AEFIHVLGNAHVYNNHIDSLKIQLNRIPYPFPTLKLNPDIKNIEDFTISDFTIQNYVHHE
KISMDMAA
NT seq
1827 nt
NT seq
+upstream
nt +downstream
nt
atgatggaacaagtctgcgacgttttcgatatttatgccatatgtgcatgttgtaaggtt
gaaaataaaaatgaggtgaaaaaaaacgaggtttttaataattacacatttagaggttta
ggaaataaaggagtattaccatggaaatgtaattcactagatatgaaatatttttgtgcc
gttactacatatgtgaatgaatcaaaatatgaaaaattgaaatataaaagatgtaaatat
ttaaacaaagaaacgctgaataatgcaatggatatgcctaattcgaaaaaattacaaaat
gttgtagttatgggaagaacaagttgggaaagtattccaaaaaaatttaaacctttaagc
aaccgaataaatgttatattgtcgagaacattaaaaaaagaagattttgatgaagatgtt
tatatcattaacacagttgaagatttaatagttttacttggaaaattaaattattataaa
tgttttattattggaggttcagttgtttataaagaatttttagaaaagaaattaatcaaa
aagatatactttactagaataaatagttcatatgaatgtgatgtattttttccagaaata
aatgaaaatgagtatcaaattatttctgttagtgatgtatatacttgtaacaatacaaca
ctagattttgttatttataagaaaaagaataatcaagtgttaaatgaaaaagactgtata
gaaggagaagaaaaaaataatgatatgtctttaaaaaatgatgacaaagatacatgtcct
atgaaaaaattaacagaattttataaaaatgtagacaaatataaaattaattatgaaaat
gataatgatgatgatgaagaagatgattttgtttattttaattttaataaagaaaaagaa
gagaaaaataaaaattgtgtacatccaaatgattttaaaatatataatagtttgaaacat
aaatgtcatcctgaatatcaatatttaaatattatatatgatattataatgaatggaaat
aaacaaagtgatcgaacaggagtaggtgttttaagtaaattcggatatattatgaaattt
gatttaagtcaatatttcccattattaactacaaagaaattattcttaagaggaattatt
gaagaattgctttggtttgttagaggagaaacaaatggtaatacactgttaaataagaat
gtaaggatatgggaagctaatggtactagagaatttttagataatagaaaattatttcat
agagaagttaacgatttaggacctatttatggttttcaatggagacatttcggagctgaa
tatacaaatatgcatgataattatgaaaataaaggagttgatcaattaaaaaatataata
aatttaattaaaaatgatcctacaagtagaagaattcttttgtgtgcatggaatgtaaaa
gatcttgatcaaatggcattacctccttgtcatattttatgtcaattttatgttttcgat
ggaaaattatcatgtattatgtatcaaaggtcatgtgatttaggactaggagtacctttt
aatattgcatcctattctatttttactcatatgattgcacaagtctgtaatttgcaacct
gccgaatttatacacgttttaggaaatgcacatgtttataataatcacattgatagttta
aaaatccaacttaatagaataccatatccattcccaacacttaaattaaatccagatatt
aaaaatattgaagattttacaatttcggactttacaatacaaaattatgttcatcatgaa
aaaatttcaatggatatggctgcctaa
DBGET
integrated database retrieval system
