Peromyscus leucopus (white-footed mouse): 114698857
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Entry
114698857 CDS
T07241
Symbol
Adam17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17 isoform X1
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
pleu
Peromyscus leucopus (white-footed mouse)
Pathway
pleu04148
Efferocytosis
pleu04330
Notch signaling pathway
pleu04668
TNF signaling pathway
pleu05010
Alzheimer disease
pleu05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pleu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
114698857 (Adam17)
04668 TNF signaling pathway
114698857 (Adam17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
114698857 (Adam17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
114698857 (Adam17)
09164 Neurodegenerative disease
05010 Alzheimer disease
114698857 (Adam17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
pleu01002
]
114698857 (Adam17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pleu04090
]
114698857 (Adam17)
Enzymes [BR:
pleu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
114698857 (Adam17)
Peptidases and inhibitors [BR:
pleu01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
114698857 (Adam17)
CD molecules [BR:
pleu04090
]
Proteins
114698857 (Adam17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_5
Reprolysin_2
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
114698857
NCBI-ProteinID:
XP_028733536
LinkDB
All DBs
Position
22:49989557..50035909
Genome browser
AA seq
827 aa
AA seq
DB search
MRQRLLFLTALVSFVLAPRPPEETGSGSQPRLEKLDSLLSDYDILSLSNIHQHSVRKRDL
QSATHLETLLTFSALKRHFKLYLTSSTERFSQNFRVVVVDGKKESEYSVKWQDFFSGHVV
GEPDSRVLAHIGDGDVTVRINMDGAEYNVEPLWRFVNDTKDKRMLVYKSEDIKDVSRLQS
PKVCGYLKADSEELLPKGLIDREPSEEFVRRVKRRAEPDPLKNTCKLLVVADHRFYKYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGERHFNM
AKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPGGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCNSDCTLKPGVRCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGDAEDDTVCLDLGKCKAGKCIPFCKREQELESCACADTDNSC
KVCCRNLSGPCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLS
INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHHSNIEMLSSMD
SASVRIIKPFPAPQTPGRLQPLQPASMMPPGSAAPKLDHQRMDTIQEDPSTDSHVDDDGF
EKDPFPNSSAAAKSFEDLTDHPVTRSEKAASFKLQRQSRVDSKETEC
NT seq
2484 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagcgtctcctcttcctgaccgccctggtgtctttcgtcctggcgccccgacct
ccggaggaaacgggctctggctcccagccgaggctcgagaagcttgactctttgctctca
gactacgatatcctctctttgtctaatattcatcagcactccgtgaggaaaagggaccta
cagtctgcgacgcacttagaaacactgctaactttttcagctttgaaaaggcattttaaa
ttatacctgacatcaagtactgaacgcttttcgcagaacttcagagtcgtggtggtggat
gggaaaaaggaaagcgagtacagtgtgaaatggcaggacttcttcagcgggcacgtggtc
ggtgagcctgactctagggttctagcccacataggcgatggtgatgttacagtgagaatc
aacatggatggggcagagtataacgtggagccactttggaggtttgttaatgatactaaa
gataaaagaatgttagtgtataagtctgaagatatcaaggatgtttcacgtctgcaatct
ccaaaagtgtgtggctatttaaaggcggatagtgaagagttgcttccaaaaggactcata
gacagagagccatctgaagagtttgttcggcgagtgaagagacgagctgagcctgacccc
ttgaagaacacttgtaagttactggtggtagcggatcaccgattctataagtacatgggc
cgaggagaggagagcaccaccaccaactacttaatagagctaattgaccgagttgatgac
atataccggaacacttcgtgggataatgcgggctttaaaggttatggaatacagatagaa
cagattcgaattcttaagtctccacaagaagtaaaacctggtgaaaggcacttcaatatg
gccaaaagttacccaaacgaagaaaaagatgcttgggatgtgaagatgttgctggagcaa
tttagctttgatatagccgaagaagcctccaaagtctgcctggctcatcttttcacgtac
caggactttgacatgggaactcttggattagcttacgtgggttctcccagagccaacagt
cacggaggggtttgcccaaaagcttactacagcccaggtgggaagaaaaacatctatttg
aatagtggtctgactagtacaaaaaattatggtaaaaccatccttacaaaggaagctgac
ctggttacaactcatgaattgggacacaattttggggcagaacatgatcctgatgggcta
gcagaatgtgctccaaatgaggaccagggaggaaagtatgttatgtaccccatcgctgtg
agtggtgaccacgagaacaataagatgttttccaactgcagcaaacagtccatctacaag
accatagagagcaaggctcaggagtgcttccaggagcgcagtaacaaggtgtgcggaaac
tccagggtggacgaaggggaggagtgtgacccgggcatcatgtacctcaacaacgacacc
tgctgcaacagcgactgcacgctgaagcccggtgtgcggtgcagtgataggaacagccct
tgctgtaaaaactgtcagttcgagacagcccagaagaagtgccaggaggccattaacgcc
acttgcaaaggcgtgtcctactgcacagggaatagcagtgagtgccccccaccaggagat
gcagaagatgacaccgtgtgcctggacctcggcaagtgcaaggctggaaaatgcattccc
ttctgcaaaagagagcaggagctggagtcgtgtgcgtgcgccgacaccgacaactcgtgc
aaggtgtgctgcaggaacctctctggcccgtgtgtgccctacgtggatgcggagcagaag
aacttgtttttgaggaaagggaagccctgtacggtcgggttttgtgacatgaatggcaaa
tgtgaaaagcgagtacaggatgtcattgagcgtttctgggatttcattgaccagttgagc
atcaacacttttgggaagttcttggcagacaacatcgtagggtccgtcctggttttctcc
ttgatattctggattcctttcagcattcttgtccactgtgtggacaagaaactggacaag
cagtatgaatccctatctctgtttcaccacagtaacattgagatgctgagcagcatggat
tcggcctctgttcgcatcatcaagcctttccctgcaccgcagactccgggtcgtctgcag
cccctgcagccggcctccatgatgccgccagggtctgcggctccaaagctggaccaccag
aggatggacaccatccaggaagaccccagcacagactcccacgtggacgatgatggcttc
gagaaggaccccttccccaacagcagtgcggccgccaagtccttcgaggacctcaccgac
cacccggtcaccaggagcgagaaggcagcctccttcaagctgcagcgccagagccgagtg
gacagcaaggagacagagtgctaa
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