Entry
Name
ABC transporters - Paracoccus marcusii
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Other DBs
Organism
Paracoccus marcusii [GN:
pmau ]
Gene
CP157_00092 ugpC_1; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
CP157_00478 mglA_1; Galactose/methyl galactoside import ATP-binding protein MglA [KO:K23537 ]
CP157_00581 mglA_2; Galactose/methyl galactoside import ATP-binding protein MglA [KO:K23537 ]
CP157_00821 ptxB; putative phosphite transport system-binding protein PtxB [KO:K02044 ]
CP157_00828 ugpA_1; sn-glycerol-3-phosphate transport system permease protein UgpA [KO:K10228 ]
CP157_00830 malK_1; Maltose/maltodextrin import ATP-binding protein MalK [KO:K10111 ] [EC:7.5.2.-]
CP157_00879 ugpA_2; sn-glycerol-3-phosphate transport system permease protein UgpA [KO:K05814 ]
CP157_00880 ugpB; sn-glycerol-3-phosphate-binding periplasmic protein UgpB [KO:K05813 ]
CP157_01423 mlaD; putative phospholipid ABC transporter-binding protein MlaD [KO:K02067 ]
CP157_01438 opuAB; Glycine betaine transport system permease protein OpuAB [KO:K02001 ]
CP157_01488 livH_1; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
CP157_01489 livF_1; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
CP157_01490 lptB_2; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995 ]
CP157_01491 braC_1; Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
CP157_01532 mlaE; putative phospholipid ABC transporter permease protein MlaE [KO:K02066 ]
CP157_01533 mkl; putative ribonucleotide transport ATP-binding protein mkl [KO:K02065 ]
CP157_01621 lolC; Lipoprotein-releasing system transmembrane protein LolC [KO:K09808 ]
CP157_01622 lolD; Lipoprotein-releasing system ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
CP157_02019 gbuC; Glycine betaine/carnitine transport binding protein GbuC [KO:K02002 ]
CP157_02342 livF_2; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
CP157_02343 lptB_3; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995 ]
CP157_02345 livH_2; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
CP157_02346 braC_2; Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
CP157_02354 hpf; Putative metal ABC transporter substrate-binding protein Hpf [KO:K11604 ]
CP157_02368 potB_2; Spermidine/putrescine transport system permease protein PotB [KO:K11071 ]
CP157_02434 yhdY; Inner membrane amino-acid ABC transporter permease protein YhdY [KO:K09971 ]
CP157_02435 glnM; putative glutamine ABC transporter permease protein GlnM [KO:K09970 ]
CP157_02436 yhdW; Putative amino-acid ABC transporter-binding protein YhdW [KO:K09969 ]
CP157_02583 livH_3; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K11960 ]
CP157_02586 livF_3; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K11963 ]
CP157_02897 livF_4; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
CP157_02900 livH_4; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
CP157_03289 livH_5; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
CP157_03290 livF_5; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
CP157_03291 lptB_4; Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995 ]
CP157_03321 ousW; Glycine betaine/choline transport system permease protein OusW [KO:K02001 ]
CP157_03368 ugpC_3; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K17324 ]
CP157_03400 ugpC_4; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K10111 ] [EC:7.5.2.-]
CP157_03423 yfiZ; putative siderophore transport system permease protein YfiZ [KO:K23186 ]
CP157_03424 yfhA_2; putative siderophore transport system permease protein YfhA [KO:K23187 ]
CP157_03425 yusV_2; putative siderophore transport system ATP-binding protein YusV [KO:K23188 ]
CP157_03450 phnD1; putative ABC transporter phosphite binding protein PhnD1 [KO:K02044 ]
CP157_03533 fhuB; Iron(3+)-hydroxamate import system permease protein FhuB [KO:K23228 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway