Pongo abelii (Sumatran orangutan): 100174617
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Entry
100174617 CDS
T01416
Symbol
AKR1C3
Name
(RefSeq) aldo-keto reductase family 1 member C3
KO
K04119
aldo-keto reductase family 1 member C3 [EC:
1.1.1.51
1.1.1.188
1.1.1.213
1.1.1.357
]
Organism
pon
Pongo abelii (Sumatran orangutan)
Pathway
pon00140
Steroid hormone biosynthesis
pon00590
Arachidonic acid metabolism
pon00790
Folate biosynthesis
pon01100
Metabolic pathways
pon04913
Ovarian steroidogenesis
pon05208
Chemical carcinogenesis - reactive oxygen species
Module
pon_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pon_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pon00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
100174617 (AKR1C3)
00590 Arachidonic acid metabolism
100174617 (AKR1C3)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100174617 (AKR1C3)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
100174617 (AKR1C3)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
100174617 (AKR1C3)
Enzymes [BR:
pon01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase
100174617 (AKR1C3)
1.1.1.188 prostaglandin-F synthase
100174617 (AKR1C3)
1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
100174617 (AKR1C3)
1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase
100174617 (AKR1C3)
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Paralog
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Motif
Pfam:
Aldo_ket_red
Motif
Other DBs
NCBI-GeneID:
100174617
NCBI-ProteinID:
NP_001127540
Ensembl:
ENSPPYG00000002052
UniProt:
Q5R7C9
LinkDB
All DBs
Position
8:5165983..5179136
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AA seq
323 aa
AA seq
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MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPM
SLKPGEELSPTDENGKVIFDIVDLCTTWEAMEECKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPV
LCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTAEDMRAIDGLN
RNLHYFNSDSLASHPNYPYSDEY
NT seq
972 nt
NT seq
+upstream
nt +downstream
nt
atggattccaaacaccagtgtgtgaagctaaatgatggccacttcatgcctgtattggga
tttggcacctatgcacctccagaggttccgagaagtaaagctttggaggttacaaaatta
gcaatagaagctggcttccgccatatagattctgctcatttatacaataatgaggagcag
gttggactggccatccgaagcaagattgcagatggcagtgtgaagagagaagacatattc
tacacttcaaagctttggtccacttttcatcgaccagagttggtccgaccagccttggaa
aactcgctgaaaaaagctcaattggactatgttgacctctatcttattcattctccaatg
tctctaaagccaggtgaggaactttcaccaacagatgaaaatggaaaagtgatatttgac
atagtggacctctgtaccacctgggaggccatggaggagtgtaaggatgcaggattggcc
aagtccattggggtgtcaaacttcaaccgcaggcagctggagatgatcctcaacaagcca
ggactcaagtacaagcccgtctgcaaccaggtggaatgtcatccgtatttcaaccggagt
aaattgctagatttctgcaagtcaaaagatattgttctggttgcctatagtgccctggga
tctcaacgagacaaacgatgggtggacccgaactccccggttctcttggaggacccagtc
ctttgtgccttggcaaaaaagcacaagcgaaccccagccctgattgccctgcgctaccag
cttcagcgtggggttgtggtcctggccaagagctacaatgagcagcggatcagagagaat
gtccaggtttttgaattccagttgactgcagaggacatgagagccatagatggcctaaac
agaaatctccactattttaacagtgatagtcttgctagccaccctaattatccatattca
gatgaatattaa
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