Pongo abelii (Sumatran orangutan): 100435491 Help Entry 100435491         CDS       T01416                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism pon  Pongo abelii (Sumatran orangutan) Pathway pon01524   Platinum drug resistance pon04010   MAPK signaling pathway pon04115   p53 signaling pathway pon04148   Efferocytosis pon04210   Apoptosis pon04215   Apoptosis - multiple species pon04623   Cytosolic DNA-sensing pathway pon04650   Natural killer cell mediated cytotoxicity pon04657   IL-17 signaling pathway pon04668   TNF signaling pathway pon04726   Serotonergic synapse pon04932   Non-alcoholic fatty liver disease pon04933   AGE-RAGE signaling pathway in diabetic complications pon04936   Alcoholic liver disease pon05010   Alzheimer disease pon05012   Parkinson disease pon05014   Amyotrophic lateral sclerosis pon05016   Huntington disease pon05020   Prion disease pon05022   Pathways of neurodegeneration - multiple diseases pon05132   Salmonella infection pon05133   Pertussis pon05134   Legionellosis pon05145   Toxoplasmosis pon05146   Amoebiasis pon05152   Tuberculosis pon05160   Hepatitis C pon05161   Hepatitis B pon05162   Measles pon05163   Human cytomegalovirus infection pon05164   Influenza A pon05165   Human papillomavirus infection pon05167   Kaposi sarcoma-associated herpesvirus infection pon05168   Herpes simplex virus 1 infection pon05169   Epstein-Barr virus infection pon05170   Human immunodeficiency virus 1 infection pon05200   Pathways in cancer pon05203   Viral carcinogenesis pon05205   Proteoglycans in cancer pon05206   MicroRNAs in cancer pon05210   Colorectal cancer pon05222   Small cell lung cancer pon05416   Viral myocarditis pon05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pon00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100435491 (CASP3)    04668 TNF signaling pathway     100435491 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     100435491 (CASP3)   09143 Cell growth and death    04210 Apoptosis     100435491 (CASP3)    04215 Apoptosis - multiple species     100435491 (CASP3)    04115 p53 signaling pathway     100435491 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     100435491 (CASP3)    04650 Natural killer cell mediated cytotoxicity     100435491 (CASP3)    04657 IL-17 signaling pathway     100435491 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     100435491 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100435491 (CASP3)    05206 MicroRNAs in cancer     100435491 (CASP3)    05205 Proteoglycans in cancer     100435491 (CASP3)    05203 Viral carcinogenesis     100435491 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     100435491 (CASP3)    05222 Small cell lung cancer     100435491 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100435491 (CASP3)    05161 Hepatitis B     100435491 (CASP3)    05160 Hepatitis C     100435491 (CASP3)    05164 Influenza A     100435491 (CASP3)    05162 Measles     100435491 (CASP3)    05168 Herpes simplex virus 1 infection     100435491 (CASP3)    05163 Human cytomegalovirus infection     100435491 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     100435491 (CASP3)    05169 Epstein-Barr virus infection     100435491 (CASP3)    05165 Human papillomavirus infection     100435491 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     100435491 (CASP3)    05133 Pertussis     100435491 (CASP3)    05134 Legionellosis     100435491 (CASP3)    05152 Tuberculosis     100435491 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     100435491 (CASP3)    05145 Toxoplasmosis     100435491 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     100435491 (CASP3)    05012 Parkinson disease     100435491 (CASP3)    05014 Amyotrophic lateral sclerosis     100435491 (CASP3)    05016 Huntington disease     100435491 (CASP3)    05020 Prion disease     100435491 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     100435491 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100435491 (CASP3)    05416 Viral myocarditis     100435491 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100435491 (CASP3)    04932 Non-alcoholic fatty liver disease     100435491 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     100435491 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100435491 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pon01002]     100435491 (CASP3) Enzymes [BR:pon01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      100435491 (CASP3) Peptidases and inhibitors [BR:pon01002]  Cysteine peptidases   Family C14: caspase family    100435491 (CASP3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 Glycos_trans_3N SICA_beta Motif Other DBs NCBI-GeneID:  100435491 NCBI-ProteinID:  XP_002815385 Ensembl:  ENSPPYG00000037417 UniProt:  A0A6D2X1B2 LinkDB All DBs Position 3:complement(206910545..206932821) Genome browser AA seq 277 aa AA seqDB search MENTENSVDSKSIKNLEPKVIHGSKSMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG MASRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVAKEDHSKRSSFVCVLLS HGEEGIIFGTNGPVDLRKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN RKVATEFESFSLDATFHAKKQIPCIVSMLTKELYFYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacactgaaaactcagtggattcaaaatccattaaaaatttggaaccaaaggtc atacatggaagcaaatcgatggactctggaatatccctggacaacagttataaaatggat tatcctgagatgggtttatgtataataattaataataagaattttcataaaagcactgga atggcatctcggtctggtacagatgtcgatgcagcaaacctcagggaaacattcagaaac ttgaaatatgaagtcaggaataaaaatgatcttacacgtgaagaaattgtggaactgatg cgtgatgttgctaaagaagatcacagcaaaaggagcagttttgtttgtgtgcttctgagc cacggtgaagaagggataatttttggaacaaatgggcctgttgacctgagaaaaataaca aactttttcagaggggatcgttgtagaagtctaactggaaaacccaaacttttcattatt caggcctgccgtggtacagaactggactgtggcattgagacagacagtggtgttgatgat gacatggcgtgtcataaaataccagtggaggctgacttcttgtatgcatactccacagca cctggttattattcttggcgaaattcaaaggatggctcctggttcatccagtcgctttgt gccatgctgaaacagtacgccgacaagcttgaatttatgcacattcttacccgggttaac cgaaaggtggcaacagagtttgagtccttttcccttgacgctacttttcatgcaaagaaa cagataccatgtattgtttccatgctcacaaaagaactctatttttatcactaa

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