Panthera pardus (leopard): 109251018 Help Entry 109251018         CDS       T06062                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X1   KO K02187   caspase 3 [EC:3.4.22.56] Organism ppad  Panthera pardus (leopard) Pathway ppad01524   Platinum drug resistance ppad04010   MAPK signaling pathway ppad04115   p53 signaling pathway ppad04148   Efferocytosis ppad04210   Apoptosis ppad04215   Apoptosis - multiple species ppad04623   Cytosolic DNA-sensing pathway ppad04650   Natural killer cell mediated cytotoxicity ppad04657   IL-17 signaling pathway ppad04668   TNF signaling pathway ppad04726   Serotonergic synapse ppad04932   Non-alcoholic fatty liver disease ppad04933   AGE-RAGE signaling pathway in diabetic complications ppad04936   Alcoholic liver disease ppad05010   Alzheimer disease ppad05012   Parkinson disease ppad05014   Amyotrophic lateral sclerosis ppad05016   Huntington disease ppad05020   Prion disease ppad05022   Pathways of neurodegeneration - multiple diseases ppad05132   Salmonella infection ppad05133   Pertussis ppad05134   Legionellosis ppad05145   Toxoplasmosis ppad05146   Amoebiasis ppad05152   Tuberculosis ppad05160   Hepatitis C ppad05161   Hepatitis B ppad05162   Measles ppad05163   Human cytomegalovirus infection ppad05164   Influenza A ppad05165   Human papillomavirus infection ppad05167   Kaposi sarcoma-associated herpesvirus infection ppad05168   Herpes simplex virus 1 infection ppad05169   Epstein-Barr virus infection ppad05170   Human immunodeficiency virus 1 infection ppad05200   Pathways in cancer ppad05203   Viral carcinogenesis ppad05205   Proteoglycans in cancer ppad05206   MicroRNAs in cancer ppad05210   Colorectal cancer ppad05222   Small cell lung cancer ppad05416   Viral myocarditis ppad05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ppad00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109251018 (CASP3)    04668 TNF signaling pathway     109251018 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     109251018 (CASP3)   09143 Cell growth and death    04210 Apoptosis     109251018 (CASP3)    04215 Apoptosis - multiple species     109251018 (CASP3)    04115 p53 signaling pathway     109251018 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     109251018 (CASP3)    04650 Natural killer cell mediated cytotoxicity     109251018 (CASP3)    04657 IL-17 signaling pathway     109251018 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     109251018 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109251018 (CASP3)    05206 MicroRNAs in cancer     109251018 (CASP3)    05205 Proteoglycans in cancer     109251018 (CASP3)    05203 Viral carcinogenesis     109251018 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     109251018 (CASP3)    05222 Small cell lung cancer     109251018 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     109251018 (CASP3)    05161 Hepatitis B     109251018 (CASP3)    05160 Hepatitis C     109251018 (CASP3)    05164 Influenza A     109251018 (CASP3)    05162 Measles     109251018 (CASP3)    05168 Herpes simplex virus 1 infection     109251018 (CASP3)    05163 Human cytomegalovirus infection     109251018 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     109251018 (CASP3)    05169 Epstein-Barr virus infection     109251018 (CASP3)    05165 Human papillomavirus infection     109251018 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     109251018 (CASP3)    05133 Pertussis     109251018 (CASP3)    05134 Legionellosis     109251018 (CASP3)    05152 Tuberculosis     109251018 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     109251018 (CASP3)    05145 Toxoplasmosis     109251018 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     109251018 (CASP3)    05012 Parkinson disease     109251018 (CASP3)    05014 Amyotrophic lateral sclerosis     109251018 (CASP3)    05016 Huntington disease     109251018 (CASP3)    05020 Prion disease     109251018 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     109251018 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     109251018 (CASP3)    05416 Viral myocarditis     109251018 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     109251018 (CASP3)    04932 Non-alcoholic fatty liver disease     109251018 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     109251018 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     109251018 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ppad01002]     109251018 (CASP3) Enzymes [BR:ppad01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      109251018 (CASP3) Peptidases and inhibitors [BR:ppad01002]  Cysteine peptidases   Family C14: caspase family    109251018 (CASP3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 Motif Other DBs NCBI-GeneID:  109251018 NCBI-ProteinID:  XP_019277850 Ensembl:  ENSPPRG00000014967 UniProt:  A0A9V1EB70 LinkDB All DBs Position Unknown AA seq 303 aa AA seqDB search MGSTFTSGRLEKTWENSRRQVLEVPMENSENSVDAKSIKNSETRKIFHGSKSMDSGIYMD NSYKMDYPEMGLCIIINNKNFHESTGMPSRSGTDVDAANLRETFTNLKYEVRNKNDLTRE QIVALLDSVSREDHSKRSSFICVLLSHGDEGIIYGTNGPVDLKKLTGFFRGDYCRSLTGK PKLFIIQACRGTELDCGIETDSGTEDDIACQKIPVEADFLYAYSTAPGYYSWRNSKDGSW FIQSLCSMLRLYAHKLEFVHILTRVNRKVALEFESFSLDSAFHGKKQIPCIVSMLTKELY FYH NT seq 912 nt NT seq  +upstreamnt  +downstreamnt atgggaagtacctttacttctggaaggctagagaagacatgggagaactccagaagacaa gtattagaagtacccatggagaacagtgaaaactcagtggatgcaaaatccattaaaaat tcggaaaccagaaagatcttccatggaagcaaatcaatggactctggaatatacatggac aacagttacaaaatggattaccctgaaatgggtttatgtataataattaataataagaac tttcatgaaagtaccggaatgccgtctcggtctggtacagatgtggatgcggcgaacctc cgagaaacattcacaaacttgaaatacgaagtcaggaataaaaacgatcttacacgcgaa caaattgtggcattgctggacagtgtttctagagaagatcatagcaaaaggagcagtttt atttgcgtgcttctaagccacggtgatgaaggaatcatttatggaacaaacggacctgtt gacctgaaaaaattgacaggtttcttcagaggggattattgtagaagtctaaccggcaaa cccaaactcttcattattcaggcctgccgaggcacggaactggactgcggcattgagact gacagtggtaccgaggatgacatcgcctgccagaaaataccagtggaagccgacttctta tatgcgtattccacagcccctggttactactcctggcgaaattccaaggatggatcctgg ttcatccagtcactttgctcgatgctcagactgtatgctcacaagcttgagttcgtgcac attcttactcgggttaaccgaaaggtagctctagaatttgagtccttttctcttgactct gcttttcatggaaagaaacagattccatgtattgtgtctatgctcacaaaagaactatat ttttatcactga

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