Pteronotus mesoamericanus (Parnell's mustached bat): 129068492
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Entry
129068492 CDS
T09558
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
ppam
Pteronotus mesoamericanus (Parnell's mustached bat)
Pathway
ppam00350
Tyrosine metabolism
ppam00790
Folate biosynthesis
ppam01100
Metabolic pathways
ppam04728
Dopaminergic synapse
ppam04917
Prolactin signaling pathway
ppam05012
Parkinson disease
ppam05030
Cocaine addiction
ppam05031
Amphetamine addiction
ppam05034
Alcoholism
Module
ppam_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
ppam00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
129068492 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
129068492 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
129068492 (TH)
09156 Nervous system
04728 Dopaminergic synapse
129068492 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
129068492 (TH)
09165 Substance dependence
05030 Cocaine addiction
129068492 (TH)
05031 Amphetamine addiction
129068492 (TH)
05034 Alcoholism
129068492 (TH)
Enzymes [BR:
ppam01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
129068492 (TH)
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Paralog
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
129068492
NCBI-ProteinID:
XP_054426686
LinkDB
All DBs
Position
Unknown
AA seq
493 aa
AA seq
DB search
MPSPGSNAPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAEAAAAAEP
AQPLGAGACVERDGKARLSLLFTLRGTKPSPLSRALKVFETFEAQILHLETRPAQRPRAG
APHLEFFLRCEVPGADLHTLLSSLRRVAEDVRGAGESKVLWFPRKVSELDKCHHLVTKFD
PDLDLDHPGFSDQAYRQRRKQIAEIAFQHKHGDPIPRVEYTAEEIATWKEVYTTLKGLYA
THACREHLEAFELLERCSGYREDNIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLA
FRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIE
KLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSAEPEIRPFDPDAAALQPYQD
QTYQSVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPQAIRRSLEDVQD
ELQTLSHALNALA
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcccagtcccggcagcaacgcgccgcaggccaagggcttccgcagggccgtctccgag
ctggacgccaagcaggccgaggccatcatgtccccgcgcttcatcgggcggaggcagagc
ctcatcgaggacgcgcgcaaggagcgggagaaggcggaggcggcggcggccgcggagccg
gcgcagcccctgggggccggggcgtgcgtggagagggacgggaaggcccggctgagcctg
ctcttcaccctgcggggcaccaagccctcgccgctctcccgtgccctgaaggtgttcgag
acgttcgaagcccaaatcctgcacctggagacccggccggcgcagcggccgcgggcaggg
gcgccccacctggagttcttcctgcgctgcgaggtgcccggcgccgacctgcacaccctg
ctgagctccctgcgccgggtggcggaggatgtgcgtggcgcgggggagagcaaagtcctc
tggttcccgaggaaagtttctgagctggacaagtgccaccacctggtcaccaagttcgat
cccgacctggacttggatcacccgggcttctcggaccaggcgtaccgccagcgccggaag
cagatcgccgagatcgccttccagcacaagcacggtgatcccattccccgggtggagtac
acggccgaggagatcgccacctggaaggaggtgtacaccacgctcaagggcctgtacgcc
acccacgcctgccgggagcacctggaggcgttcgagctgctggagcgctgcagcgggtac
cgggaggacaacatcccgcagctggaagacgtctcccgcttcctgaaggagcggaccggc
ttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctggcc
ttccgcgtgttccagtgcacccagtacatccggcacgcctcctcgcccatgcactccccc
gagcccgactgctgccacgagctgctggggcatgtgcccatgctggccgaccggaccttt
gcccagttctcccaggacatcggcctggcgtccctgggagcctcagacgaggaaatcgag
aagctgtccacactgtactggttcaccgtggagttcgggctgtgcaagcaaaacggggag
gtgaaggcctacggagccgggctgctctcctcctacggggagctcctgcactccctgtcg
gcggagcccgagatccggcccttcgaccccgacgctgcggccctgcagccctaccaggac
cagacgtaccagtccgtgtacttcgtgtccgagagcttcagcgacgccaaggacaagctc
aggagctacgcctcccgcattcagcgtcctttctccgtgaagttcgacccgtacacgctg
gccatcgacgtgctggacagtccccaagcgatccggcgctccctggaggacgtccaggac
gagctgcagaccctcagccacgcgctgaacgccctcgcctaa
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