KEGG   Phocoena phocoena (harbor porpoise): 136118038
Entry
136118038         CDS       T11058                                 
Name
(RefSeq) dihydrodiol dehydrogenase 3
  KO
K04119  aldo-keto reductase family 1 member C3 [EC:1.1.1.51 1.1.1.188 1.1.1.213 1.1.1.357]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc00140  Steroid hormone biosynthesis
pphc00590  Arachidonic acid metabolism
pphc00790  Folate biosynthesis
pphc01100  Metabolic pathways
pphc04913  Ovarian steroidogenesis
pphc05208  Chemical carcinogenesis - reactive oxygen species
Module
pphc_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pphc_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    136118038
   00590 Arachidonic acid metabolism
    136118038
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    136118038
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    136118038
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    136118038
Enzymes [BR:pphc01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase
     136118038
    1.1.1.188  prostaglandin-F synthase
     136118038
    1.1.1.213  3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
     136118038
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     136118038
SSDB
Motif
Pfam: Aldo_ket_red
Other DBs
NCBI-GeneID: 136118038
NCBI-ProteinID: XP_065727223
LinkDB
Position
2:complement(151880261..151895625)
AA seq 323 aa
MDPKCQCLELNDGHFIPILGFGTYAPEEVPKSEALEVTKFAIDVGFRHIDCAHLYQNEEQ
VGQAIRSKIADGTVKREDIFYTSKLWSTFLRPELVQPALEKSLKNLQLDYVDLYIIHFPA
ALKPGEELFPKDENGKMIFDTVDLCRTWEVLEKCKDAGLAKSIGVSNFNRKQLEKILNKP
GLKYKPVCNQVECHPYLNQSKLLDFCKSNDIVLVAYGALGSQRLKDWVNPSYPILLEDPV
LCAIAKKHKQTPALIALRYQMQRGVVVLAKSYNKKRIKENMQVLDFELTPEDMKAIDGLN
SNVRYYDLLFISDHPDYPYSEEY
NT seq 972 nt   +upstreamnt  +downstreamnt
atggaccccaaatgccagtgtctggaacttaatgatggccacttcattcccattctggga
tttggaacctatgcccctgaggaggttcctaagagtgaagctctggaggtcaccaaattt
gctattgatgttgggttccgccatattgactgtgctcatttgtaccaaaatgaagagcag
gttggacaggccattcgcagcaagattgcagatggcactgtgaagagagaagacatattc
tacacttcaaagctttggtccactttccttcgaccagagttggttcaaccagccttggaa
aagtcactgaaaaatcttcaactggattatgttgacctctatattattcattttccagcg
gctctgaagccaggggaggaactttttcccaaagatgaaaatggaaaaatgatatttgac
acagtggatctctgtcgcacgtgggaggtcctggagaagtgtaaggacgcaggactggcc
aagtccattggggtgtccaactttaaccgcaaacagctggagaagatcctgaacaagcca
gggctcaagtacaagcctgtctgcaaccaggtggaatgtcatccttatctcaatcagagc
aaactgttggacttctgcaagtcaaacgatattgttcttgttgcctatggtgctctggga
tcccaacgattaaaagactgggtgaacccaagctacccaattctcttggaggacccagtt
ctttgtgccattgcaaaaaagcacaagcaaaccccagcactgattgcccttcgctaccag
atgcaacgtggggttgtggtcctggccaagagttacaataagaagcggatcaaagagaac
atgcaggttctcgattttgaattaactccagaagacatgaaagcaattgatggtctcaac
agtaatgtacgatattatgatttactcttcatttctgatcaccctgactatccatattct
gaagaatattga

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