Phocoena phocoena (harbor porpoise): 136121646
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Entry
136121646 CDS
T11058
Symbol
MTHFR
Name
(RefSeq) methylenetetrahydrofolate reductase (NADPH) isoform X1
KO
K25004
methylenetetrahydrofolate reductase (NADPH) [EC:
1.5.1.53
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc00670
One carbon pool by folate
pphc01100
Metabolic pathways
pphc01523
Antifolate resistance
pphc04981
Folate transport and metabolism
Brite
Enzymes [BR:
pphc01000
]
1. Oxidoreductases
1.5 Acting on the CH-NH group of donors
1.5.1 With NAD+ or NADP+ as acceptor
1.5.1.53 methylenetetrahydrofolate reductase (NADPH)
136121646 (MTHFR)
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Gene cluster
GFIT
Motif
Pfam:
MTHFR_C
MTHFR
DUF6919
Motif
Other DBs
NCBI-GeneID:
136121646
NCBI-ProteinID:
XP_065731635
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Position
1:complement(9076333..9089345)
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AA seq
696 aa
AA seq
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MDRPKPRVLPAGHCCPSLGMRAWEAGSARFSVPPSISRSSAMVNEPRGHGGPSPRWEGSS
SGSESSKDSSRCSTPVLDPERHERLREKMKRRVESGDKWFSLEFFPPRTAEGAVNLISRF
DRMGAGGPLFIDVTWHPAGDPGSDKETSSMVIASTAVNYCGLETILHMTCCHQSREEITG
HLHKAKRLGLKNILALRGDPTGDQWEEEDGGFNYAVDLVKHIRSEFGDYFDVCVAGYPKG
HPDAESFEAGLKHLKEKVAAGADFVITQLFFEADTFFRFVRACSEIGITCPILPGIFPIQ
GYRSLRQLVKLSKLEVPQQIKDVIEPIKDNDAAIRNYGIEQALSLCRELLASGSVPGLHF
YTLNREVATTEVLKRLGMWIEDPRRPLPWAISAHPKRREEDVRPIFWASRPKSYIYRTQE
WDEFPNGRWGNSSSPAFGELKDYYLFYLKSKSPKEELLKMWGEELTSEESVFEVFAHYLS
GEPNQNGYKVTCLPWNDEPLAAETSLMKEELLRVNRRGILTINSQPNINGKPSSDPVVGW
GPGGGYVFQKAYLEFFTSRETVEALLQVLKKYELRVNYHIVNVKGDNITNAPELQPNAVT
WGIFPGREIIQPTVVDPVSFMFWKDEAFALWIEQWGKLYEEESPSRTIIQYIHDSYFLVN
LVDNEFPLDSCLWQVVEDTFELLSGPPQGKRETEAP
NT seq
2091 nt
NT seq
+upstream
nt +downstream
nt
atggaccgtccaaaacccagggtgctcccggcggggcactgctgcccctccctgggaatg
cgggcctgggaggccggcagcgcgaggttctcagtgccaccctccatcagcaggagctca
gccatggtgaacgaacccagagggcatggcggccccagcccccgctgggagggcagcagc
agtggcagcgagagctccaaggatagttcaaggtgttccacaccggtgctggaccccgaa
cgacacgagaggctcagggagaagatgaagcggagggtggaatctggggacaagtggttc
tccctagaattcttccctcctcgaactgctgagggagccgtcaatctcatctcaaggttt
gaccggatgggggcaggtggtcccctcttcatagatgtgacctggcatccagcaggggac
cctggctcagacaaggagacttcgtccatggtgatcgccagcaccgccgtgaactactgt
ggcctggagaccatcctgcacatgacctgctgccatcagagccgggaagagatcacgggc
cacctgcacaaggctaagcgtctgggcctgaagaacatcctggcgctgaggggagacccc
acaggtgaccagtgggaagaggaggacggaggcttcaactacgccgtagacttggtgaag
cacatccgaagcgagtttggtgactacttcgatgtctgtgtggcaggttaccccaaaggc
caccccgacgcagagagctttgaggctggcctgaagcacctgaaggagaaggtggccgcg
ggagccgacttcgtcatcacccagctcttctttgaggccgacactttcttccgctttgtt
agggcttgctccgagataggcattacttgccccatcctccctggaatcttccctattcag
ggctaccgctccctccggcagcttgtaaagctgtccaagctggaggtgccacagcagatc
aaggacgtgatcgagccaatcaaagacaatgacgccgccatccgtaactacggcatcgag
caggcgctgagcctgtgccgggagcttctggcaagcggctcggtgccgggcctgcacttc
tacaccctcaaccgcgaggtggccaccacagaggtgctgaagcgcttgggcatgtggatc
gaggaccccagacgtcccctgccctgggccatcagtgcccaccccaagcgccgggaggaa
gatgtccgtcccatcttctgggcctccagaccaaagagttacatttatcgcacccaggag
tgggatgagttccccaacggccgctggggcaattcctcctctccggcctttggggagctg
aaggactactacctcttctacctgaagagcaagtccccaaaggaagagctgctgaagatg
tggggggaggagctgaccagtgaagaaagtgtctttgaagtctttgcccactacctctcg
ggagagccgaaccagaacggctataaagtgacttgcctgccctggaatgatgagcccctg
gcggccgagaccagcctgatgaaggaggagctgctgcgcgtgaaccggcggggcatcctc
accatcaactcccagcccaacatcaacgggaagccgtcctccgaccccgtcgtgggctgg
ggccccggtgggggctatgtcttccagaaggcctacttagagttcttcacttcccgagag
acagtggaggcgcttttgcaggtgctgaagaagtacgagctccgggtgaattaccacatc
gtgaatgtaaagggtgacaacatcaccaacgcccccgagctgcagcccaacgccgtcact
tggggcatcttccctgggcgagagatcatccagcccacagtggtggacccagtcagcttc
atgttctggaaggacgaggccttcgccctgtggatcgagcagtggggcaagctgtatgag
gaggagtccccgtcccgcacgatcatccagtacatccacgacagctacttcttggtcaac
ctggtggacaacgagttcccgctggacagctgtctgtggcaggtggtggaagacacgttt
gagcttctcagcgggcccccccagggcaagagggagacagaggcgccgtga
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