Phocoena phocoena (harbor porpoise): 136134121
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Entry
136134121 CDS
T11058
Symbol
ADAM17
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 17
KO
K06059
disintegrin and metalloproteinase domain-containing protein 17 [EC:
3.4.24.86
]
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc04148
Efferocytosis
pphc04330
Notch signaling pathway
pphc04668
TNF signaling pathway
pphc05010
Alzheimer disease
pphc05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
136134121 (ADAM17)
04668 TNF signaling pathway
136134121 (ADAM17)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
136134121 (ADAM17)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
136134121 (ADAM17)
09164 Neurodegenerative disease
05010 Alzheimer disease
136134121 (ADAM17)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
pphc01002
]
136134121 (ADAM17)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pphc04090
]
136134121 (ADAM17)
Enzymes [BR:
pphc01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.86 ADAM 17 endopeptidase
136134121 (ADAM17)
Peptidases and inhibitors [BR:
pphc01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
136134121 (ADAM17)
CD molecules [BR:
pphc04090
]
Proteins
136134121 (ADAM17)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Reprolysin_2
Reprolysin_5
ADAM17_MPD
Disintegrin
Reprolysin_3
Reprolysin
Reprolysin_4
Pep_M12B_propep
Motif
Other DBs
NCBI-GeneID:
136134121
NCBI-ProteinID:
XP_065747659
LinkDB
All DBs
Position
14:83401587..83452821
Genome browser
AA seq
830 aa
AA seq
DB search
MRQCVLFLSSLVPFVLAPRPPDEPGFGSPQRLEKLDSLLSDYDILSLSNIQQHSVRKRDL
QASTHLETLLIFSALKRHFKLYLTSSTERFSQNFKVVVVDGKDESEYPVKWQDFFSGHVV
GEPDSRVLAHIGDDDITIRINTDGVEYSIEPLWRLINDTKDKRVLVYKSEDIKNVSRLQS
PKVCGYIKADNEELLPKGLVGREPPDELVHRVKRRADPNPLKNTCKLLVVADHRFYRYMG
RGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVRPGERHFNM
AKSYPSEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANS
HGGVCPKAYYSPIGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGL
AECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGN
SRVDEGEECDPGIMYLNNDTCCDSDCMLRPGVRCSDRNSPCCKNCQFETAQKKCQEAINA
TCKGVSYCTGNSSECPPPGDAADDTVCLDLGKCKDGKCVPFCEREQRLESCACNETDNSC
KVCCRDPSGRCLPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWEFIDKLS
INTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQFESLSLFHPSNVEMLSSMD
SASVRVIKPFPAPLTPGRLQPPQPAPAVPPAPLVPVAPKLDHQRMDTIQEDPSMDSHADE
DGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKASSFKLQRQNRIDSKETEC
NT seq
2493 nt
NT seq
+upstream
nt +downstream
nt
atgaggcagtgtgtccttttcctgagcagtttggttcctttcgtgctggcgccgcgaccg
ccggacgagccgggcttcggctccccccagcgactcgaaaagcttgattctttgctctca
gactacgatatcctctctttatcgaatatccaacagcactctgtaagaaaaagggatcta
caggcttcaacacacttagaaacactactaattttttcagccttgaaaaggcattttaaa
ttatacctgacatcaagtactgaacgcttttcccaaaacttcaaagtcgtggtggtagat
gggaaagatgaaagcgagtaccccgtcaaatggcaggacttcttcagtggacatgtggtt
ggtgagcctgactctagggttctagcccacataggagatgatgatattacaataagaatc
aacacagatggggtggaatatagtatagagccactttggagactaattaatgatactaaa
gacaaaagagtgttagtttataaatctgaagatatcaagaatgtttcacgtttgcagtct
ccaaaagtgtgtggttatataaaggcggataatgaagagttgcttccaaaagggctggta
ggcagagagccacctgatgagcttgttcatcgggtgaagagaagagctgaccctaatccc
ctgaagaacacgtgtaaattattggtggtagcagatcatcgcttttacagatacatgggc
agaggggaagagagtacaactacaaactacttgatagagctaattgacagagttgatgac
atctatcggaacacttcatgggacaatgcaggttttaaaggttatggaatacagatagag
cagattcgcattctcaagtctccacaagaggtaagacctggtgaaaggcacttcaatatg
gcaaaaagttacccaagtgaagaaaaggatgcttgggacgtgaagatgctgctagagcaa
tttagctttgatatagctgaagaagcatctaaagtctgcctagcacatcttttcacctac
caagattttgatatgggaactcttggattagcttatgttggttctcccagagcaaacagt
catggaggtgtttgcccaaaggcttattatagtccaattggaaagaaaaatatctatttg
aatagtggtttgaccagcacaaaaaattatggtaaaaccatccttacaaaggaagctgac
ctcgttacaacgcatgagttggggcacaattttggagcagaacacgatccagatggtcta
gcagaatgtgccccaaatgaggaccagggaggaaagtatgttatgtatcccatagctgtg
agtggcgatcatgagaacaataagatgttttcaaactgcagtaaacagtcgatctataag
accattgaaagtaaggcccaggagtgttttcaagaacgcagcaacaaagtgtgcgggaac
tccagggtggacgagggggaggagtgtgaccccggcatcatgtacctgaacaacgacact
tgctgcgacagtgactgcatgctgaggccgggcgtccggtgcagtgacaggaacagtcct
tgctgtaaaaactgtcagttcgagacggcccagaagaagtgccaagaggccattaatgct
acttgcaaaggcgtgtcttactgcacaggtaacagcagtgagtgcccccctcctggcgat
gctgccgacgacacggtgtgcttggatctcggcaagtgtaaagatggcaagtgtgtgccc
ttctgcgagcgggagcagaggctggagtcctgcgcgtgtaacgaaaccgacaactcgtgc
aaggtgtgctgcagggacccctcgggccgctgcctgccctatgtcgacgccgaacagaag
aacttatttttgaggaagggaaagccctgtacagtaggattttgtgacatgaatggcaaa
tgtgagaagcgagtgcaggatgtcattgagcggttctgggagttcattgacaagctgagc
atcaatactttcgggaagtttttagcagacaacatcgtaggctccgtcctggttttctcc
ttgatattttggattcctttcagcattctggtccattgtgtggataagaaactggacaag
cagtttgaatcgctgtctctgttccaccccagtaacgtcgagatgctgagcagcatggat
tccgcttcggttcgcgtcatcaagccctttcccgcgcccctgaccccgggccgcctgcag
cccccacagcctgcccctgcggtgccccccgcgcctttggtgcctgtggccccgaagctg
gaccaccagcggatggacaccatccaggaggaccccagcatggattcgcacgccgacgag
gacggcttcgagaaggaccccttcccaaatagcagcacggccgccaagtcgttcgaggac
ctcacggaccatccggtcaccagaagcgaaaaggcctcgtcctttaagctgcagcgtcag
aaccgcattgacagcaaggaaaccgagtgctag
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