Pan paniscus (bonobo): 100974934 Help Entry 100974934         CDS       T02283                                  Symbol CASP3 Name (RefSeq) caspase-3 isoform X1   KO K02187   caspase 3 [EC:3.4.22.56] Organism pps  Pan paniscus (bonobo) Pathway pps01524   Platinum drug resistance pps04010   MAPK signaling pathway pps04115   p53 signaling pathway pps04148   Efferocytosis pps04210   Apoptosis pps04215   Apoptosis - multiple species pps04623   Cytosolic DNA-sensing pathway pps04650   Natural killer cell mediated cytotoxicity pps04657   IL-17 signaling pathway pps04668   TNF signaling pathway pps04726   Serotonergic synapse pps04932   Non-alcoholic fatty liver disease pps04933   AGE-RAGE signaling pathway in diabetic complications pps04936   Alcoholic liver disease pps05010   Alzheimer disease pps05012   Parkinson disease pps05014   Amyotrophic lateral sclerosis pps05016   Huntington disease pps05020   Prion disease pps05022   Pathways of neurodegeneration - multiple diseases pps05132   Salmonella infection pps05133   Pertussis pps05134   Legionellosis pps05145   Toxoplasmosis pps05146   Amoebiasis pps05152   Tuberculosis pps05160   Hepatitis C pps05161   Hepatitis B pps05162   Measles pps05163   Human cytomegalovirus infection pps05164   Influenza A pps05165   Human papillomavirus infection pps05167   Kaposi sarcoma-associated herpesvirus infection pps05168   Herpes simplex virus 1 infection pps05169   Epstein-Barr virus infection pps05170   Human immunodeficiency virus 1 infection pps05200   Pathways in cancer pps05203   Viral carcinogenesis pps05205   Proteoglycans in cancer pps05206   MicroRNAs in cancer pps05210   Colorectal cancer pps05222   Small cell lung cancer pps05416   Viral myocarditis pps05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pps00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100974934 (CASP3)    04668 TNF signaling pathway     100974934 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     100974934 (CASP3)   09143 Cell growth and death    04210 Apoptosis     100974934 (CASP3)    04215 Apoptosis - multiple species     100974934 (CASP3)    04115 p53 signaling pathway     100974934 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     100974934 (CASP3)    04650 Natural killer cell mediated cytotoxicity     100974934 (CASP3)    04657 IL-17 signaling pathway     100974934 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     100974934 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100974934 (CASP3)    05206 MicroRNAs in cancer     100974934 (CASP3)    05205 Proteoglycans in cancer     100974934 (CASP3)    05203 Viral carcinogenesis     100974934 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     100974934 (CASP3)    05222 Small cell lung cancer     100974934 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100974934 (CASP3)    05161 Hepatitis B     100974934 (CASP3)    05160 Hepatitis C     100974934 (CASP3)    05164 Influenza A     100974934 (CASP3)    05162 Measles     100974934 (CASP3)    05168 Herpes simplex virus 1 infection     100974934 (CASP3)    05163 Human cytomegalovirus infection     100974934 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     100974934 (CASP3)    05169 Epstein-Barr virus infection     100974934 (CASP3)    05165 Human papillomavirus infection     100974934 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     100974934 (CASP3)    05133 Pertussis     100974934 (CASP3)    05134 Legionellosis     100974934 (CASP3)    05152 Tuberculosis     100974934 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     100974934 (CASP3)    05145 Toxoplasmosis     100974934 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     100974934 (CASP3)    05012 Parkinson disease     100974934 (CASP3)    05014 Amyotrophic lateral sclerosis     100974934 (CASP3)    05016 Huntington disease     100974934 (CASP3)    05020 Prion disease     100974934 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     100974934 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100974934 (CASP3)    05416 Viral myocarditis     100974934 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     100974934 (CASP3)    04932 Non-alcoholic fatty liver disease     100974934 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     100974934 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     100974934 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pps01002]     100974934 (CASP3) Enzymes [BR:pps01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      100974934 (CASP3) Peptidases and inhibitors [BR:pps01002]  Cysteine peptidases   Family C14: caspase family    100974934 (CASP3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 SICA_beta Motif Other DBs NCBI-GeneID:  100974934 NCBI-ProteinID:  XP_003823509 Ensembl:  ENSPPAG00000029792 LinkDB All DBs Position 3:complement(182351669..182373528) Genome browser AA seq 292 aa AA seqDB search MAAIVRRLWKLIKVSMENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMG LCIIINNKNFHKSTGMTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSK EDHSKRSSFVCVLLSHGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRG TELDCGIETDSGVDDDMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQ YADKLEFMHILTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH NT seq 879 nt NT seq  +upstreamnt  +downstreamnt atggctgctattgtgaggcggttgtggaagttaataaaggtatccatggagaacaccgaa aactcagtggattcaaaatccattaaaaatttggaaccaaagatcatacatggaagcgaa tcgatggactctggaatatccctggacaacagttataaaatggattatcctgagatgggt ttatgtataatcattaataataagaattttcataaaagcactggaatgacatctcggtct ggtacagatgtcgatgcagcaaacctcagggaaacattcagaaacttgaaatatgaagtc aggaataaaaatgatcttacacgtgaagaaattgtggaattgatgcgtgatgtttctaaa gaagatcacagcaaaaggagcagttttgtttgtgtgcttctgagccatggtgaagaagga ataatttttggaacaaatggacctgttgacctgaaaaaaataacaaactttttcagaggg gatcgttgtagaagtctaactggaaaacccaaacttttcattattcaggcctgccgtggt acagaactggactgtggcattgagacagacagtggtgttgatgatgacatggcgtgtcat aaaataccagtggaggccgacttcttgtatgcatactccacagcacctggttattattct tggcgaaattcaaaggatggctcctggttcatccagtcgctttgtgccatgctgaaacag tatgccgacaagcttgaatttatgcacattcttacccgggttaaccgaaaggtggcaaca gaatttgagtccttttcctttgacgctacttttcatgcaaagaaacagattccatgtatt gtttccatgctcacaaaagaactctatttttatcactaa

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