KEGG   PATHWAY: ppsu02010
Entry
ppsu02010                   Pathway                                
Name
ABC transporters - Planktothrix pseudagardhii
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
ppsu02010  ABC transporters
ppsu02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Planktothrix pseudagardhii [GN:ppsu]
Gene
NO713_00199  zurA; Zinc uptake system ATP-binding protein ZurA [KO:K09817] [EC:7.2.2.20]
NO713_00200  znuA; High-affinity zinc uptake system binding-protein ZnuA [KO:K09815]
NO713_00247  nrtB; Nitrate transport permease protein NrtB [KO:K15577]
NO713_00251  cmpD; Bicarbonate transport ATP-binding protein CmpD [KO:K15578] [EC:7.3.2.4]
NO713_00345  mdlA; Multidrug resistance-like ATP-binding protein MdlA [KO:K18889]
NO713_00745  TGD3; Protein TRIGALACTOSYLDIACYLGLYCEROL 3, chloroplastic [KO:K02065]
NO713_00878  yurN; putative ABC transporter permease protein YurN [KO:K17245]
NO713_00903  livF; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K11963]
NO713_01173  ykfD; Putative oligopeptide transport ATP-binding protein YkfD [KO:K10823]
NO713_01287  [KO:K02066]
NO713_01369  malK; Trehalose/maltose import ATP-binding protein MalK [KO:K10112] [EC:7.5.2.-]
NO713_01528  [KO:K02471]
NO713_01752  potA; Spermidine/putrescine import ATP-binding protein PotA [KO:K11072] [EC:7.6.2.11]
NO713_01953  ycf22; putative protein ycf22 [KO:K02067]
NO713_02013  araQ; L-arabinose transport system permease protein AraQ [KO:K17246]
NO713_02087  [KO:K16785]
NO713_02198  ssuA; Putative aliphatic sulfonates-binding protein [KO:K15553]
NO713_02441  artQ; Arginine transport system permease protein ArtQ [KO:K17077 K23059]
NO713_02442  artM; Arginine transport ATP-binding protein ArtM [KO:K23060]
NO713_02451  ABCI11; ABC transporter I family member 11, chloroplastic [KO:K16787] [EC:7.-.-.-]
NO713_02520  lktB; Leukotoxin translocation ATP-binding protein LktB [KO:K11004]
NO713_02621  yvgL; Putative ABC transporter substrate-binding lipoprotein YvgL [KO:K02020]
NO713_02622  yvgM; Putative molybdenum transport system permease protein YvgM [KO:K02017 K02018] [EC:7.3.2.5]
NO713_02625  cysA; Sulfate/thiosulfate import ATP-binding protein CysA [KO:K02045] [EC:7.3.2.3]
NO713_02626  cysW; Sulfate transport system permease protein CysW [KO:K02047]
NO713_02627  cysT; Sulfate transport system permease protein CysT [KO:K02046]
NO713_02629  sbpA; Sulfate-binding protein [KO:K23163]
NO713_02905  lptB; Lipopolysaccharide export system ATP-binding protein LptB [KO:K06861] [EC:7.5.2.5]
NO713_02906  lptG; Lipopolysaccharide export system permease protein LptG [KO:K11720]
NO713_03032  [KO:K09816]
NO713_03291  livF; High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
NO713_03292  livG; High-affinity branched-chain amino acid transport ATP-binding protein LivG [KO:K01995]
NO713_03293  livM; High-affinity branched-chain amino acid transport system permease protein LivM [KO:K01998]
NO713_03294  livH; High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
NO713_03295  [KO:K01999]
NO713_03504  amiC; Aliphatic amidase expression-regulating protein [KO:K11959]
NO713_03505  braD; High-affinity branched-chain amino acid transport system permease protein BraD [KO:K11960]
NO713_03506  [KO:K11961]
NO713_03507  livG; High-affinity branched-chain amino acid transport ATP-binding protein LivG [KO:K11962]
NO713_03591  opuAA; Glycine betaine transport ATP-binding protein OpuAA [KO:K02000] [EC:7.6.2.9]
NO713_04112  pstS; Phosphate-binding protein PstS [KO:K02040]
NO713_04161  ecfA; Energy-coupling factor transporter ATP-binding protein EcfA [KO:K16786] [EC:7.-.-.-]
NO713_04206  bztD; Glutamate/glutamine/aspartate/asparagine transport ATP-binding protein BztD [KO:K09972] [EC:7.4.2.1]
NO713_04209  aapM; General L-amino acid transport system permease protein AapM [KO:K09971]
NO713_04210  yhdX; Putative amino-acid ABC transporter permease protein YhdX [KO:K09970]
NO713_04211  aapJ; General L-amino acid-binding periplasmic protein AapJ [KO:K09969]
NO713_04252  cmpA; Bicarbonate-binding protein CmpA [KO:K11950]
NO713_04253  cmpB; Bicarbonate transport system permease protein CmpB [KO:K11951]
NO713_04254  cmpC; Bicarbonate transport ATP-binding protein CmpC [KO:K11952] [EC:7.3.2.-]
NO713_04255  cmpD; Bicarbonate transport ATP-binding protein CmpD [KO:K11953] [EC:7.3.2.-]
NO713_04447  sbpA; Sulfate-binding protein [KO:K23163]
NO713_04556  bioY; putative biotin transporter BioY [KO:K03523]
NO713_04558  pstS; Phosphate-binding protein PstS [KO:K02040]
NO713_04559  pstC; Phosphate transport system permease protein PstC [KO:K02037]
NO713_04560  pstA; Phosphate transport system permease protein PstA [KO:K02038]
NO713_04561  pstB; Phosphate import ATP-binding protein PstB [KO:K02036] [EC:7.3.2.1]
NO713_04706  nikMN; Fused nickel transport protein NikMN [KO:K02007]
NO713_04707  cbiQ; Cobalt transport protein CbiQ [KO:K02008]
NO713_04708  [KO:K02006]
NO713_04713  ssuB; Aliphatic sulfonates import ATP-binding protein SsuB [KO:K15555] [EC:7.6.2.14]
NO713_04714  ssuC; Putative aliphatic sulfonates transport permease protein SsuC [KO:K15554]
NO713_04716  ssuA; Putative aliphatic sulfonates-binding protein [KO:K15553]
NO713_04741  ycjN; Putative ABC transporter periplasmic-binding protein YcjN [KO:K17244]
NO713_04783  cysA2; Sulfate/thiosulfate import ATP-binding protein CysA 2 [KO:K02010] [EC:7.2.2.7]
NO713_04784  fbpB; Fe(3+)-transport system permease protein SfuB [KO:K02011]
NO713_04836  potB; Spermidine/putrescine transport system permease protein PotB [KO:K11071]
NO713_04837  potI; Putrescine transport system permease protein PotI [KO:K11070]
NO713_04838  potD; Spermidine/putrescine-binding periplasmic protein [KO:K11069]
NO713_04839  potA; Spermidine/putrescine import ATP-binding protein PotA [KO:K11072] [EC:7.6.2.11]
NO713_04869  nrtA; Nitrate transport protein NrtA [KO:K15576]
NO713_04870  nrtB; Nitrate transport permease protein NrtB [KO:K15577]
NO713_04871  nrtC; Nitrate transport ATP-binding protein NrtC [KO:K15578] [EC:7.3.2.4]
NO713_04889  oppD; Oligopeptide transport ATP-binding protein OppD [KO:K15583]
NO713_04940  hepA; Heterocyst differentiation ATP-binding protein HepA [KO:K11085] [EC:7.5.2.6]
NO713_04990  potI; Putrescine transport system permease protein PotI [KO:K11070]
NO713_04991  potB; Spermidine/putrescine transport system permease protein PotB [KO:K11071]
NO713_04992  potD; Spermidine/putrescine-binding periplasmic protein [KO:K11069]
NO713_05282  malK; Maltose/maltodextrin import ATP-binding protein MalK [KO:K10112] [EC:7.5.2.-]
NO713_05319  [KO:K16915]
NO713_05320  [KO:K02007]
NO713_05321  [KO:K02008]
NO713_05322  [KO:K02006]
NO713_05414  sphX; Protein SphX [KO:K02040]
NO713_05502  exp8; Putative ABC transporter ATP-binding protein exp8 [KO:K18890]
NO713_05587  idiA; Iron deficiency-induced protein A [KO:K02012]
NO713_05647  paxB; Exotoxin translocation ATP-binding protein PaxB [KO:K11004]
NO713_05657  abcA; ABC transporter protein AbcA [KO:K09691] [EC:7.5.2.14]
NO713_05658  rfbA; O-antigen export system permease protein RfbA [KO:K09690]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   

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