Pongo pygmaeus (Bornean orangutan): 129034663 Help Entry 129034663         CDS       T10128                                  Symbol CASP3 Name (RefSeq) caspase-3   KO K02187   caspase 3 [EC:3.4.22.56] Organism ppyg  Pongo pygmaeus (Bornean orangutan) Pathway ppyg01524   Platinum drug resistance ppyg04010   MAPK signaling pathway ppyg04115   p53 signaling pathway ppyg04148   Efferocytosis ppyg04210   Apoptosis ppyg04215   Apoptosis - multiple species ppyg04623   Cytosolic DNA-sensing pathway ppyg04650   Natural killer cell mediated cytotoxicity ppyg04657   IL-17 signaling pathway ppyg04668   TNF signaling pathway ppyg04726   Serotonergic synapse ppyg04932   Non-alcoholic fatty liver disease ppyg04933   AGE-RAGE signaling pathway in diabetic complications ppyg04936   Alcoholic liver disease ppyg05010   Alzheimer disease ppyg05012   Parkinson disease ppyg05014   Amyotrophic lateral sclerosis ppyg05016   Huntington disease ppyg05020   Prion disease ppyg05022   Pathways of neurodegeneration - multiple diseases ppyg05132   Salmonella infection ppyg05133   Pertussis ppyg05134   Legionellosis ppyg05145   Toxoplasmosis ppyg05146   Amoebiasis ppyg05152   Tuberculosis ppyg05160   Hepatitis C ppyg05161   Hepatitis B ppyg05162   Measles ppyg05163   Human cytomegalovirus infection ppyg05164   Influenza A ppyg05165   Human papillomavirus infection ppyg05167   Kaposi sarcoma-associated herpesvirus infection ppyg05168   Herpes simplex virus 1 infection ppyg05169   Epstein-Barr virus infection ppyg05170   Human immunodeficiency virus 1 infection ppyg05200   Pathways in cancer ppyg05203   Viral carcinogenesis ppyg05205   Proteoglycans in cancer ppyg05206   MicroRNAs in cancer ppyg05210   Colorectal cancer ppyg05222   Small cell lung cancer ppyg05416   Viral myocarditis ppyg05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ppyg00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     129034663 (CASP3)    04668 TNF signaling pathway     129034663 (CASP3)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     129034663 (CASP3)   09143 Cell growth and death    04210 Apoptosis     129034663 (CASP3)    04215 Apoptosis - multiple species     129034663 (CASP3)    04115 p53 signaling pathway     129034663 (CASP3)  09150 Organismal Systems   09151 Immune system    04623 Cytosolic DNA-sensing pathway     129034663 (CASP3)    04650 Natural killer cell mediated cytotoxicity     129034663 (CASP3)    04657 IL-17 signaling pathway     129034663 (CASP3)   09156 Nervous system    04726 Serotonergic synapse     129034663 (CASP3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     129034663 (CASP3)    05206 MicroRNAs in cancer     129034663 (CASP3)    05205 Proteoglycans in cancer     129034663 (CASP3)    05203 Viral carcinogenesis     129034663 (CASP3)   09162 Cancer: specific types    05210 Colorectal cancer     129034663 (CASP3)    05222 Small cell lung cancer     129034663 (CASP3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     129034663 (CASP3)    05161 Hepatitis B     129034663 (CASP3)    05160 Hepatitis C     129034663 (CASP3)    05164 Influenza A     129034663 (CASP3)    05162 Measles     129034663 (CASP3)    05168 Herpes simplex virus 1 infection     129034663 (CASP3)    05163 Human cytomegalovirus infection     129034663 (CASP3)    05167 Kaposi sarcoma-associated herpesvirus infection     129034663 (CASP3)    05169 Epstein-Barr virus infection     129034663 (CASP3)    05165 Human papillomavirus infection     129034663 (CASP3)   09171 Infectious disease: bacterial    05132 Salmonella infection     129034663 (CASP3)    05133 Pertussis     129034663 (CASP3)    05134 Legionellosis     129034663 (CASP3)    05152 Tuberculosis     129034663 (CASP3)   09174 Infectious disease: parasitic    05146 Amoebiasis     129034663 (CASP3)    05145 Toxoplasmosis     129034663 (CASP3)   09164 Neurodegenerative disease    05010 Alzheimer disease     129034663 (CASP3)    05012 Parkinson disease     129034663 (CASP3)    05014 Amyotrophic lateral sclerosis     129034663 (CASP3)    05016 Huntington disease     129034663 (CASP3)    05020 Prion disease     129034663 (CASP3)    05022 Pathways of neurodegeneration - multiple diseases     129034663 (CASP3)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     129034663 (CASP3)    05416 Viral myocarditis     129034663 (CASP3)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     129034663 (CASP3)    04932 Non-alcoholic fatty liver disease     129034663 (CASP3)    04933 AGE-RAGE signaling pathway in diabetic complications     129034663 (CASP3)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     129034663 (CASP3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ppyg01002]     129034663 (CASP3) Enzymes [BR:ppyg01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.56  caspase-3      129034663 (CASP3) Peptidases and inhibitors [BR:ppyg01002]  Cysteine peptidases   Family C14: caspase family    129034663 (CASP3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 Glycos_trans_3N SICA_beta Motif Other DBs NCBI-GeneID:  129034663 NCBI-ProteinID:  XP_054340086 LinkDB All DBs Position 3:complement(198000944..198023265) Genome browser AA seq 277 aa AA seqDB search MENTENSVDSKSIKNLEPKVIHGSKSMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG MASRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVAKEDHSKRSSFVCVLLS HGEEGIIFGTNGPVDLRKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN RKVATEFESFSLDATFHAKKQIPCIVSMLTKELYFYH NT seq 834 nt NT seq  +upstreamnt  +downstreamnt atggagaacactgaaaactcagtggattcaaaatccattaaaaatttggaaccaaaggtc atacatggaagcaaatcgatggactctggaatatccctggacaacagttataaaatggat tatcctgagatgggtttatgtataataattaataataagaattttcataaaagcactgga atggcatctcggtctggtacagatgtcgatgcagcaaacctcagggaaacattcagaaac ttgaaatatgaagtcaggaataaaaatgatcttacacgtgaagaaattgtggaactgatg cgtgatgttgctaaagaagatcacagcaaaaggagcagttttgtttgtgtgcttctgagt cacggtgaagaagggataatttttggaacaaatgggcctgttgacctgagaaaaataaca aactttttcagaggggatcgttgtagaagtctaactggaaaacccaaacttttcattatt caggcctgccgtggtacagaactggactgtggcattgagacagacagtggtgttgatgat gacatggcgtgtcataaaataccagtggaggctgacttcttgtatgcatactccacagca cctggttattattcttggcgaaattcaaaggatggctcctggttcatccaatcgctttgt gccatgctgaaacagtacgccgacaagcttgaatttatgcacattcttacccgggttaac cgaaaggtggcaacagagtttgagtccttttcccttgacgctacttttcatgcaaagaaa cagataccatgtattgtttccatgctcacaaaagaactctatttttatcactaa

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