Pan troglodytes (chimpanzee): 450608
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Entry
450608 CDS
T01005
Symbol
IDE
Name
(RefSeq) insulin-degrading enzyme isoform X2
KO
K01408
insulysin [EC:
3.4.24.56
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr03266
Virion - Herpesvirus
ptr05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03266 Virion - Herpesvirus
450608 (IDE)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
450608 (IDE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
ptr01002
]
450608 (IDE)
Enzymes [BR:
ptr01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.24 Metalloendopeptidases
3.4.24.56 insulysin
450608 (IDE)
Peptidases and inhibitors [BR:
ptr01002
]
Metallo peptidases
Family M16: pitrilysin family
450608 (IDE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_M16_M
Peptidase_M16_C
Peptidase_M16
PqqF-like_C_4
Motif
Other DBs
NCBI-GeneID:
450608
NCBI-ProteinID:
XP_009457216
Ensembl:
ENSPTRG00000002757
VGNC:
7230
UniProt:
A0A2I3ST00
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All DBs
Position
8:complement(104692763..104814727)
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AA seq
1019 aa
AA seq
DB search
MRYRLAWLLHPALSSTFRSVLGARLPPPERLCGFQKKTYSKMNNPAIKRIGNHITKSPED
KREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIAGLSHFCEHMLFLGTKK
YPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDESCKD
REVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVRQE
LLKFHSAYYSSNLMAVCVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQ
LYKIVPIKDIRNLYVTFPIPDLQKYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLV
GGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAV
AFRFKDKERPRGYTSKIAGILHYYPLEEVLTAEYLLEEFRPDLIEMVLDKLRPENVRVAI
VSKSFEGKTDRTEEWYGTQYKQEAIPDEVIKKWQNADLNGKFKLPTKNEFIPTNFEILPL
EKEATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSRYIYADPLHCNMTYLFIRLL
KDDLKEYTYAARLSGLSYGIASGMNAILLSVKGYNDKQPILLKKIIEKMATFEIDEKRFE
IIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLL
SRLHIEALLHGNITKQAALGIMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQ
QRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRA
NGIQGLRFIIQSEKPPHYLESRVEAFLITMEKSIEDMTEEAFQKHIQALAIRRLDKPKKL
SAECAKYWGEIISQQYNFDRDNTEVAYLKTLTKEDIIKFYKEMLAVDAPRRHKVSVHVLA
REMDSCPVVGEFPCQNDINLSQAPALPQPEVIQNMTEFKRGLPLFPLVKPHINFMAAKL
NT seq
3060 nt
NT seq
+upstream
nt +downstream
nt
atgcggtaccggctagcgtggcttctgcaccccgcactgtccagcaccttccgctcagtc
ctcggcgcccgcctgccgcctccggagcgcctgtgtggtttccaaaaaaagacttacagc
aaaatgaataatccagccatcaagagaataggaaatcacattaccaagtctcctgaagac
aagcgagaatatcgagggctagagctggccaatggtatcaaagtacttcttatcagtgat
cccaccacggataagtcatcagcagcacttgatgtgcacataggttcattgtcggatcct
ccaaatattgctggcttaagtcatttttgtgaacatatgctttttttgggaacaaagaaa
taccctaaagaaaatgaatacagccagtttctcagtgagcatgcaggaagttcaaatgcc
tttactagtggagagcataccaattactattttgatgtttctcatgaacacctagaaggt
gccctagacaggtttgcacagttttttctgtgccccttgttcgatgaaagttgcaaagac
agagaggtgaatgcagttgattcagaacatgagaagaatgtgatgaatgatgcctggaga
ctctttcaattggaaaaagctacagggaatcctaaacaccccttcagtaaatttgggaca
ggtaacaaatatactctggagactagaccaaaccaagaaggcattgatgtaagacaagag
ctactgaaattccattctgcttactattcatccaacttaatggctgtttgtgttttaggt
cgagaatctttagatgacttgactaatctggtggtaaagttattttctgaagtagagaac
aaaaatgttccattgccagaatttcctgaacaccctttccaagaagaacatcttaaacaa
ctttacaaaatagtacccattaaagatattaggaatctctatgtgacatttcccatacct
gaccttcagaaatactacaaatcaaatcctggtcattatcttggtcatctcattgggcat
gaaggtcctggaagtctgttatcagaacttaaatcaaagggctgggttaatactcttgtt
ggtgggcagaaggaaggagcccgaggttttatgttttttatcattaatgtggacttgacc
gaggaaggattattacatgttgaagatataattttgcacatgtttcaatacattcagaag
ttacgtgcagaaggacctcaagaatgggttttccaagagtgcaaggacttgaatgctgtt
gcttttaggtttaaagacaaagagaggccacggggctatacatctaagattgcaggaata
ttgcattattatcccctagaagaggtgctcacagcggaatatttactggaagaatttaga
cctgacttaatagagatggttctcgataaactcagaccagaaaatgtccgggttgccata
gtttctaaatcttttgaaggaaaaactgatcgcacagaagagtggtatggaacccagtac
aaacaagaagctataccggatgaagtcatcaagaaatggcaaaatgctgacctgaatggg
aaatttaaacttcctacaaagaatgaatttattcctacgaattttgagattttaccgtta
gaaaaagaggcgacaccataccctgctcttattaaggatacagctatgagcaaactttgg
ttcaaacaagatgataagttttttttgccgaaggcttgtctcaactttgaatttttcagt
cgctacatttatgctgatcctctccattgcaacatgacatacctgtttatcaggttattg
aaggatgatttaaaagagtatacatatgcagcacgcctctcaggtttgagctatggcatt
gcatcaggaatgaatgcaatacttctttcagtgaaaggttacaatgacaagcagccaatt
ttactaaagaagattattgagaaaatggctacctttgagattgatgaaaaaagatttgaa
attatcaaagaagcatatatgcgatctcttaacaatttccgggctgaacagcctcaccag
catgccatgtactacctccgcttgctgatgactgaagtggcctggactaaagatgagtta
aaagaagctctggatgatgtaacccttcctcgccttaaggccttcatacctcagctcctg
tcacggctgcacattgaagcccttctccatggaaacataacaaagcaggctgcattagga
attatgcagatggttgaagacaccctcattgaacatgctcataccaaacctctccttcca
agtcagctggttcggtatagagaagttcagctccctgacagaggatggtttgtttatcag
cagagaaatgaagttcacaataactgtggcatcgagatatactaccaaacagacatgcaa
agcacctcagagaatatgtttctggagctcttctgtcagattatctcggaaccttgcttc
aacaccctgcgcaccaaggagcagttgggctatatcgtcttcagcgggccacgtcgagcc
aatggcatacagggcttgagattcatcatccagtcagaaaagccacctcactacctagaa
agcagagtggaagctttcttaattaccatggaaaagtccatagaggacatgacagaagag
gccttccaaaaacacattcaagcattagcaattcgtcgactagacaaaccaaagaagcta
tctgctgagtgtgctaaatactggggagaaatcatctcccagcaatataattttgacaga
gataacactgaggttgcatatttaaagacacttaccaaggaagatatcatcaaattctac
aaggaaatgttggcagtagatgctccaaggagacataaggtatccgtccatgttcttgcc
agggaaatggattcttgtcctgttgttggagagttcccatgtcaaaatgacataaatttg
tcacaagcaccagccttgccacaacctgaagtgattcagaacatgaccgaattcaagcgt
ggtctgccactgtttccccttgtgaaaccgcatattaacttcatggctgcaaaactctga
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