Pan troglodytes (chimpanzee): 451980
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Entry
451980 CDS
T01005
Symbol
ERBB3
Name
(RefSeq) receptor tyrosine-protein kinase ErbB-3 isoform X2
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01521
EGFR tyrosine kinase inhibitor resistance
ptr04010
MAPK signaling pathway
ptr04012
ErbB signaling pathway
ptr04020
Calcium signaling pathway
ptr04151
PI3K-Akt signaling pathway
ptr05205
Proteoglycans in cancer
ptr05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
451980 (ERBB3)
04012 ErbB signaling pathway
451980 (ERBB3)
04020 Calcium signaling pathway
451980 (ERBB3)
04151 PI3K-Akt signaling pathway
451980 (ERBB3)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
451980 (ERBB3)
05205 Proteoglycans in cancer
451980 (ERBB3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
451980 (ERBB3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
451980 (ERBB3)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
451980 (ERBB3)
Protein kinases [BR:
ptr01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
451980 (ERBB3)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
GF_recep_IV
Furin-like
Pkinase
Recep_L_domain
TM_ErbB1
Kinase-like
Motif
Other DBs
NCBI-GeneID:
451980
NCBI-ProteinID:
XP_016778717
Ensembl:
ENSPTRG00000005076
VGNC:
57760
LinkDB
All DBs
Position
10:complement(39911590..39934957)
Genome browser
AA seq
1185 aa
AA seq
DB search
MDTIDWRDIVRDRDAEIVVKDNGRSCPPCHEVCKGRCWGPGSEDCQTLTKTICAPQCNGH
CFGPNPNQCCHDECAGGCSGPQDTDCFACRHFNDSGACVPRCPQPLVYNKLTFQLEPNPH
TKYQYGGVCVASCPHNFVVDQTSCVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSG
SRFQTVDSSNIDGFVNCTKILGNLDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYL
NIQSWPPHMHNFSVFSNLTTIGGRSLYNRGFSLLIMKNLNVTSLGFRSLKEISAGRIYIS
ANRQLCYHHSLNWTKVLRGPTEERLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQC
LSCRNYSRGGVCVTHCNFLNGEPREFAHEAECFSCHPECQPMEGTATCNGSGSDTCAQCA
HFRDGPHCVSSCPHGVLGAKGPIYKYPDVQNECRPCHENCTQGCKGPELQDCLGQTLVLI
GKTHLTMALTVIAGLVVIFMMLGGTFLYWRGRRIQNKRAMRRYLERGESIEPLDPSEKAN
KVLARIFKETELRKLKVLGSGVFGTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQAVT
DHMLAIGSLDHAHIVRLLGLCPGSSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQ
IAKGMYYLEEHGMVHRNLAARNVLLKSPSQVQVADFGVADLLPPDDKQLLYSEAKTPIKW
MALESIHFGKYTHQSDVWSYGVTVWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICT
IDVYMVMVKCWMIDENIRPTFKELANEFTRMARDPPRYLVIKRESGPGIAPGPEPHGLTN
KKLEEVELEPELDLDLDLEAEEDNLATTTLGSALSLPVGTLNRPRGSQSLLSPSSGYMPM
NQGNLGESCQESAVSGSSERCPRPVSLHPMPRGCLASESSEGHVTGSETELQEKVSMCRS
RSRSRSPRPRGDSAYHSQRHSLLTPVTPLSPPGLEEEDVNGYVMPDTHLKGTPSSREGTL
SSVGLSSVLGTEEEDEDEEYEYMNRRRRHSPPHPPRPSSLEELGYEYMDVGSDLSASLGS
TQSCPLHPIPIMPTAGTTPDEDYEYMNRQRDGGGPGGDYAAMGACPASEQGYEEMRAFQG
PGHQAPHVHYARLKTLRSLEATDSAFDNPDYWHSRLFPKANAQRT
NT seq
3558 nt
NT seq
+upstream
nt +downstream
nt
atggacacaattgactggagggacatcgtgagggaccgagatgctgagatagtggtgaag
gacaatggcagaagctgtccgccctgtcatgaggtttgcaaggggcgatgctggggtcct
ggatcagaagactgccagacattgaccaagaccatctgtgctcctcagtgtaatggtcac
tgctttgggcccaaccccaaccagtgctgccatgatgagtgtgccgggggctgctcaggc
cctcaggacacagactgctttgcctgccggcacttcaatgacagtggagcctgtgtacct
cgctgtccacagcctcttgtctacaacaagctaactttccagctggaacccaatccccac
accaagtatcagtatggaggagtttgtgtagccagctgtccccataactttgtggtggat
caaacatcctgtgtcagggcctgtcctcctgacaagatggaagtagataaaaatgggctc
aagatgtgtgagccttgtgggggactatgtcccaaagcctgtgagggaacaggctctggg
agccgcttccagactgtggactcgagcaacattgatggatttgtgaactgcaccaagatc
ctgggcaacctggactttctgatcaccggcctcaatggagacccctggcacaagatccct
gccctggacccagagaagctcaatgtcttccggacagtacgggagatcacaggttacctg
aacatccagtcctggccgccccacatgcacaacttcagtgttttttccaatttgacaacc
attggaggcagaagcctctacaaccggggcttctcattgttgatcatgaagaacttgaat
gtcacatctctgggcttccgatccctgaaggaaattagtgctgggcgtatctatataagt
gccaataggcagctctgctaccaccactctttgaactggaccaaggtgcttcgggggcct
acggaagagcgactagacatcaagcataatcggccgcgcagagactgcgtggcagagggc
aaagtgtgtgacccactgtgctcctctgggggatgctggggcccaggccctggtcagtgc
ttgtcctgtcgaaattatagccgaggaggtgtctgtgtgacccactgcaactttctgaat
ggggagcctcgagaatttgcccatgaggccgaatgcttctcctgccacccggaatgccaa
cccatggagggcactgccacatgcaatggctcgggctctgatacttgtgctcaatgtgcc
cattttcgagatgggccccactgtgtgagcagctgcccccatggagtcctaggtgccaag
ggcccaatctacaagtacccagatgttcagaatgaatgtcggccctgccatgagaactgc
acccaggggtgtaaaggaccagagcttcaagactgtttaggacaaacactggtgctgatc
ggcaaaacccatctgacaatggctttgacagtgatagcaggattggtagtgattttcatg
atgctgggcggcacttttctctactggcgtgggcgccggattcagaataaaagggctatg
aggcgatacttggaacggggtgagagcatagagcctctggaccccagtgagaaggctaac
aaagtcttggccagaatcttcaaagagacagagctaaggaagcttaaagtgcttggctcg
ggtgtctttggaactgtgcacaaaggagtgtggatccctgagggtgaatcaatcaagatt
ccagtctgcattaaagtcattgaggacaagagtggacggcagagttttcaagctgtgaca
gatcatatgctggccattggcagcctggaccatgcccacattgtaaggctgctgggacta
tgcccagggtcatctctgcagcttgtcactcaatatttgcctctgggttctctgctggat
catgtgagacaacaccggggggcactggggccacagctgctgctcaactggggagtacaa
attgccaagggaatgtactaccttgaggaacatggtatggtgcatagaaacctggctgcc
cgaaacgtgctactcaagtcacccagtcaggttcaggtggcagattttggtgtggctgac
ctgctgcctcctgatgataagcagctgctatacagtgaggccaagactccaattaagtgg
atggcccttgagagtatccactttgggaaatacacacaccagagtgatgtctggagctat
ggtgtgacagtttgggagttgatgaccttcggggcagagccctatgcagggctacgattg
gctgaagtaccagacctgctagagaagggggagcggttggcacagccccagatctgcaca
attgatgtctacatggtgatggtcaagtgttggatgattgatgagaacattcgcccaacc
tttaaagaactagccaatgagttcaccaggatggcccgagatccaccacggtatctggtc
ataaagagagagagtgggcctggaatagcccctggaccagagccccatggtctgacaaac
aagaagctagaggaagtagagctggagccagaactagacctagacctagacttggaagca
gaggaggacaacctggcaaccaccacactgggctccgccctcagcctaccagttggaaca
cttaatcggccacgtgggagccagagccttttaagtccatcatctggatacatgcccatg
aaccagggtaatcttggggagtcttgccaggagtctgcagtttctgggagcagtgaacgg
tgcccccgtccagtctctctacacccaatgccacggggatgcctggcatcagagtcatca
gaggggcatgtaacaggctctgagactgagctccaggagaaagtgtcaatgtgtaggagc
cggagcaggagccggagcccacggccacgcggagatagcgcctaccattcccagcgccac
agtctgcttactcctgttaccccactctccccaccagggttagaggaagaggatgtcaac
ggttatgtcatgccagatacacacctgaaaggtactccctcctcccgggaaggcaccctt
tcttcagtgggtctcagttctgtcctgggtactgaagaagaagatgaagatgaggagtat
gaatacatgaaccggaggagaaggcacagtccacctcatccccctaggccaagttccctt
gaggagctgggttatgagtacatggatgtggggtcagacctcagtgcctctctgggcagc
acacagagttgcccactccaccctatacccatcatgcctactgcaggcacaactccagat
gaagactatgaatatatgaatcggcaacgagatggaggtggtcctgggggtgattatgca
gccatgggggcctgcccagcctctgagcaagggtatgaagagatgagagcttttcagggg
cctggacatcaggccccccatgtccattatgcccgcctaaaaactctacgtagcttagag
gctacagactctgcctttgataaccctgattactggcatagcaggcttttccccaaggct
aatgcccagagaacgtaa
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