Pan troglodytes (chimpanzee): 452657 Help Entry 452657            CDS       T01005                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism ptr  Pan troglodytes (chimpanzee) Pathway ptr04022   cGMP-PKG signaling pathway ptr04068   FoxO signaling pathway ptr04081   Hormone signaling ptr04140   Autophagy - animal ptr04152   AMPK signaling pathway ptr04211   Longevity regulating pathway ptr04213   Longevity regulating pathway - multiple species ptr04910   Insulin signaling pathway ptr04920   Adipocytokine signaling pathway ptr04923   Regulation of lipolysis in adipocytes ptr04930   Type II diabetes mellitus ptr04931   Insulin resistance ptr04932   Non-alcoholic fatty liver disease ptr04935   Growth hormone synthesis, secretion and action ptr05010   Alzheimer disease ptr05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:ptr00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     452657 (IRS2)    04022 cGMP-PKG signaling pathway     452657 (IRS2)    04152 AMPK signaling pathway     452657 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     452657 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     452657 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     452657 (IRS2)    04923 Regulation of lipolysis in adipocytes     452657 (IRS2)    04920 Adipocytokine signaling pathway     452657 (IRS2)    04935 Growth hormone synthesis, secretion and action     452657 (IRS2)   09149 Aging    04211 Longevity regulating pathway     452657 (IRS2)    04213 Longevity regulating pathway - multiple species     452657 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     452657 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     452657 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     452657 (IRS2)    04932 Non-alcoholic fatty liver disease     452657 (IRS2)    04931 Insulin resistance     452657 (IRS2) SSDB OrthologParalogGFIT Motif Pfam:  IRS PH MEKK4_N Motif Other DBs NCBI-GeneID:  452657 NCBI-ProteinID:  XP_016781015 Ensembl:  ENSPTRG00000006030 VGNC:  13119 UniProt:  H2Q7S8 LinkDB All DBs Position 14:complement(115364982..115397532) Genome browser AA seq 1340 aa AA seqDB search MASPPRQGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA TAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE YFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPTAAPAASCSASLPGALGGSAGAAGA EDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTL QLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEF RPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCR VRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLP AGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQR PSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFY GYMTMDRPLSHCGRPYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL MRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGA ALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAVPSAGPAGPAPTSAAGRTFPA SGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPD FFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQ ATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGLGGGRPEGFLGQRGRAVRPTRLSLEGL PSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSL GSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLP PRPSASPSSSLQPPPPPPPPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFG VAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRA DPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGD EPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDV REEPGLPPQPQPQPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPAN TYASIDFLSHHLKEATVVKE NT seq 4023 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgcggcaggggccgcccgggccggcgagcggagacggccccaacctc aacaacaacaacaacaacaacaatcacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg acggcgggcggggggtcggcgccgcagccgccgcggctcgagtactacgagagcgagaaa aagtggcggagcaaggcaggcgcgccgaaacgggtgatcgctctcgactgctgcctgaac atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag tacttcgccgtggccgccgagaacgagcaggagcaggagggctggtaccgcgcgctcacc gacctggtcagcgagggccgcgcggccgccggagacgcgccccccaccgccgcgcccgcc gcgtcctgcagcgcctccctgcccggcgccctgggcggctctgccggcgccgccggggcc gaggacagctacgggctggtggctcccgccacggccgcctaccgtgaggtgtggcaggtg aacctgaagcccaagggtctgggccagagcaagaacctgacgggggtgtaccgtctgtgc ctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgacgctg cagctaatgaacatccgccgctgcggccactcggacagcttcttcttcatcgaggtgggc cgctcggccgtcacaggccccggcgagctgtggatgcaggcggacgactcggtggtggcg cagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttcgagttc cggccgcgcagtaagagccaatcgtcggggtcgtcggccacgcaccccatcagcgtcccc ggcgcgcgccgccaccaccacctggtcaacctgccccccagccagacgggcctggtgcgc cgctcgcgcaccgacagcctggccgccaccccgccggcggccaagtgcagctcgtgccgg gtgcgcaccgccagcgagggcgacggcggcgcggcggcgggagcggcggccgcgggcgcc aggccggtgtcggtggctgggagccctctgagccccgggccggtgcgcgcgcccctgagc cgctcgcacaccctgagcggcggctgcggcggccgcgggagcaaggtggcgctgctgccg gcagggggcgcgctgcaacacagccgctccatgtccatgcccgtggcgcactcgccgccc gccgccaccagccccggctccctgtcgtccagcagcggccacggctcgggctcctacccg ccgccgcccggcccgcacccgcctctgccgcatccgctgcaccacggccccggccagcgg ccctccagcggcagcgcctccgcctcaggctcccccagcgaccccggcttcatgtccctg gacgagtacggctccagcccaggcgacttgcgcgctttctgcagccaccgaagcaacacg cccgagtccatcgcggagacgcccccggcccgagatggcggcggcggcggtgagttctac gggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgccgggtctcg ggggacgcggcccaggacctggaccgagggctgcgcaagaggacctactccctgaccacg ccagcccggcagcggccggtgccccagccctcctctgcctcgctggatgaatacaccctg atgcgggccaccttctcgggcagcgcgggccgcctctgcccgtcctgccccgcgtcctct cccaaggtggcctaccacccctacccagaggactacggagacatcgagatcggctcccac aggagctccagcagcaatctgggggcagacgacggctacatgcccatgacccccggcgcg gccctcgcgggcagtgggagcggcagctgcaggagcgacgactacatgcccatgagcccc gccagcgtgtccgcccccaagcagatcttgcagcccagggcagccgccgccgccgccgtg ccctctgcggggcctgcggggccagcacccacctctgcggcgggcaggacattcccggcg agtgggggcggctacaaggccagctcgcccgccgagagctcccccgaggacagtgggtac atgcgcatgtggtgcggttccaagctgtccatggagcatgcagatggcaagctgctgccc aacggggactacctcaacgtgtcccccagcgacgcggtcaccacgggcaccccgcccgac ttcttctccgcagccctgcaccccggcggggagccgctcaggggcgttcccggctgctgc tacagctccttgccccgctcctacaaggccccctacacctgcggcggggacagcgaccag tacgtgctcatgagctcccccgtggggcgcatcctggaggaggagcgtctggagcctcag gccacgccagggcccagccaggcagccagcgccttcggggccggccccacgcagccccct caccctgtagtgccttcgcccgtgcggcctagcggcggcctaggcggcggccgcccggag ggcttcttgggccagcgcggccgggcggtgaggcccacgcgcctgtccctggaggggctg cccagcctgcccagcatgcacgagtatccactgccaccggagcccaagagccccggcgag tacatcaacatcgactttggcgagcccggggcccgcctgtcgccgcccgcgcctcccctg ctggcgtcggcggcctcgtcctcctcgctcttgtccgccagcagcccggcctcgtcgctg ggctcaggcaccccgggcaccagcagcgacagccgacagcggtctccgctctccgactac atgaacctcgacttcagctcccccaagtctcctaagccgggcgccccgagcggccacccc gtgggctccttggacggcctcctgtccccggaggcctcctccccgtatccgccgttgccc ccgcgtccgtccgcgtccccgtcgtcgtctctgcagccgccgccaccgccgccgcccccg ggggagctgtaccgcctgccccccgcctcggccgttgccaccgcccagggcccgggcgcc gcctcatcgttgtcctcggacaccggggacaatggtgactacaccgagatggcttttggt gtggccgccaccccgccgcaacctatcgcggcccccccgaagccagaagctgcccgcgtg gccagcccgacgtcgggcgtgaagaggctgagcctcatggagcaggtgtcgggagtcgag gccttcctgcaggccagccagcccccggacccccaccgcggcgccaaggtcatccgcgca gacccgcaggggggccgccgccgccacagttccgagaccttctcctccaccacgacggtc acccccgtgtccccgtccttcgcccacaaccccaagcgccacaactcggcctccgtggaa aatgtctctctcaggaaaagcagcgagggcggcgtgggtgtcggccctggagggggcgac gagccgcccacctccccacgacagttgcagccggcgccccctttggcaccgcagggccgg ccgtggaccccgggtcagcccgggggcttggtcggttgtcctgggagcggtggatcgcca atgcgcagagagacctctgccggcttccagaatggtctcaactacatcgccatcgacgtg agggaggagcccgggctgccaccccagccgcagccgcagccgccgccgcttcctcagccg ggagacaagagctcctggggtcggacccgaagcctcgggggtctcatcagcgctgtgggc gtcggcagcaccggcggcgggtgcggggggccgggtcccggtgccctgccccctgccaac acctacgccagcattgacttcttgtcccaccacttgaaggaggccaccgtcgtgaaagag tga

DBGET integrated database retrieval system