Pan troglodytes (chimpanzee): 454986
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Entry
454986 CDS
T01005
Symbol
FASN
Name
(RefSeq) fatty acid synthase isoform X1
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00061
Fatty acid biosynthesis
ptr01100
Metabolic pathways
ptr01212
Fatty acid metabolism
ptr04152
AMPK signaling pathway
ptr04910
Insulin signaling pathway
ptr04936
Alcoholic liver disease
Module
ptr_M00082
Fatty acid biosynthesis, initiation
ptr_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
454986 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
454986 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
454986 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
ptr01004
]
454986 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ptr04147
]
454986 (FASN)
Enzymes [BR:
ptr01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
454986 (FASN)
Lipid biosynthesis proteins [BR:
ptr01004
]
Fatty acid synthase
Animal type
454986 (FASN)
Exosome [BR:
ptr04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
454986 (FASN)
Exosomal proteins of breast milk
454986 (FASN)
Exosomal proteins of colorectal cancer cells
454986 (FASN)
Exosomal proteins of bladder cancer cells
454986 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
KAsynt_C_assoc
Ketoacyl-synt_C
FAS_pseudo-KR
ADH_zinc_N
ADH_zinc_N_2
Methyltransf_12
PKS_DH_N
PP-binding
adh_short
Methyltransf_31
Methyltransf_11
PS-DH
Thiolase_N
Methyltransf_23
DUF7080
Methyltransf_25
YjeF_N
AlaDh_PNT_C
ACP_syn_III
Motif
Other DBs
NCBI-GeneID:
454986
NCBI-ProteinID:
XP_016786455
Ensembl:
ENSPTRG00000009791
VGNC:
12131
UniProt:
K7DMP5
A0A6D2WZ06
LinkDB
All DBs
Position
19:complement(95430057..95450145)
Genome browser
AA seq
2511 aa
AA seq
DB search
MEEVVIAGMSGKLPESENLQEFWDNLIGGVDMVTDDDRRWKAGLYGLPRRSGKLKDLSRF
DASFFGVHPKQAHTMDPQLRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEAL
SRDPETLVGYSMVGCQRAMMANRLSFFFDFRGPSIALDTACSSSLMALQNAYQAIHSGQC
PAAIVGGINVLLKPNTSVQFLRLGMLSPEGTCKAFDTAGNGYCRSEGVVAVLLTKKSLAR
RVYATILNAGTNTDGFKEQGVTFPSGGIQEQLICSLYQSAGVAPESFEYIEAHGTGTKVG
DPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFH
SPNPEIPALLDGRLQVVDQPLPVRGGNVGINSFGFGGSNVHVILRPNTQPPPAPAPHATL
PRLLRASGRTPEAVQKLLEQGLRHSQDLAFLSMLNDIAAVPATAMPFRGYAVLGGEHGGP
EVQQVPAGERPLWFICSGMGTQWRGMGLSLMRLDRFRDSILRSDEAVKPFGLKVSQLLLS
TDESTFDDIVHSFVSLTAIQIGLIDLLSCMGLRPDGIVGHSLGEVACGYADGCLSQEEAV
LAAYWRGQCIKEAHLPPGAMAAVGLSWEECKQRCPPGVVPACHNSKDTVTISGPQAPVFE
FVEQLRKEGVFAKEVRTGGMAFHSYFMEAIAPPLLQELKKVIREPKPRSARWLSTSIPED
QWHSGLARTSSAEYNVNNLVSPVLFQEALWHVPEHAVVLEIAPHALLQAVLKRGLKPSCT
IIPLMKKDHRDNLEFFLAGIGRLHLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSL
AWDVPAAEDFPNGSGSPSAAVYNIDTSSESPDHYLVDHTLDGRVLFPATGYLSIVWKTLA
RALGLGVEQLPVVFEDVVLHQATILPKTGTVSLEVRLLEASRAFEVSENGNLVVSGKVYQ
WDDPDPRLFDHPESPTPNPAEPLFLAQAEVYKELRLRGYDYGPHFQGILEASLEGDSGRL
LWKDNWVSFVDTMLQMSILGSAKHGLYLPTRVTAIHIDPATHRQKLYTLQDKAQVADVVV
SRWLRVTVAGGVHISGLHTESAPRRQQEQQVPILEKFCFTPHMEEGCLSERAALQEELQL
CKGLAQALQTKVTQQGLKMVVPGLDGAQIPRDPSQQELPRLLSAACRLQLNGNLQLELAQ
VLAQERPKLPEDPLLSGLLDSPALKACLDTAVENMPSLKMKVVEVLAGHGHLYSRIPGLL
SPHPLLQLSYTATDRHPQALEAAQAELQQHDVAQGQWDPADPAPSALGSADLLVCNCAVA
ALGDPASALSNMVAALREGGFLLLHTLLRGHPLGDIVAFLTSAEPQYGQGILSQDAWESL
FSRVSLRLVGLKKSFYGSTLFLCRRPAPQDSPIFLPVDDTSFRWVESLKGILADEDSSRP
VWLKAINCATSGVVGLVNCLRREPGGNRLRCVLLSNLSSTSHVPEVDPGSAELQKVLQGD
LVMNVYRDGAWGAFRHFLLEEDKPEEPTAHAFVTTLTRGDLSSIRWVCSSLRHAQPTCPG
AQLCTVYYASLNFRDIMLATGKLSPDAIPGKWTSQDSLLGMEFSGRDASGKRVMGLVPAK
GLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGV
GQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSFEQHVLWHTGGKG
VDLVLNSLAEEKLQASVRCLATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAFF
NESSADWREVWALVQAGIRDGVVRPLKCTVFHGAQVEEAFRYMAQGKHIGKVVVQVLAEE
PEAVLKGAKPKLMSAISKTFCPAHKSYIIAGGLGGFGLELAQWLIQRGVQKLVLTSRSGI
RTGYQAKQVRRWRRQGVQVQVSTSNISSLEGARGLIAEAAQLGPVGGVFNLAVVLRDALL
ENQTPEFFQDVCKPKYSGTLNLDRVTREACPELDYFVVFSSVSCGRGNAGQSNYGFANSA
MERICEKRRHEGLPGLAVQWGAIGDVGILVETMSTNDTVVTGTLPQRMASCLEVLDLFLN
QPHMVLSSFVLAEKAAAYRDRDSQRDLVEAVAHILGIRDLAAVNLDSSLADLGLDSLMSV
EVRQTLERELNLVLSVREVRQLTLRKLQELSSKAGEANELACPTPKEDGLAQQQTQLNLR
SLLVNPEGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLASRLSIPTYGLQCTRAAPLD
SIHSLAAYYIDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQSPAPTHNSLFLFDGS
PTYVLAYTQSYRAKLTPGCEAEAETEAVCFFVQQFTDMEHNRVLEALLPLKGLEERVAAA
VDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGGAYGEDLGA
DYNLSQVCDGKVSVHVIEGDHRTLLEGSGLESIVSIIHSSLAEPRVSVREG
NT seq
7536 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggtggtgattgccggcatgtccgggaagctgccagagtcggagaacttgcag
gagttctgggacaacctcattggcggtgtggacatggtcacggacgatgaccgtcgctgg
aaggcggggctctacggcctgccccggcggtccggcaagctgaaggacctgtctaggttt
gatgcctccttcttcggagtccaccccaagcaggcacacacgatggaccctcagctgcgg
ctgctgctggaagtcacctatgaagccatcgtggacggaggcatcaacccagattcactc
cgagggacacacactggcgtctgggtgggcgtgagcggctctgagacctcggaggccctg
agccgagaccccgagacactcgtgggctacagcatggtgggctgccagcgagcgatgatg
gccaaccggctctccttcttcttcgactttagagggcccagcatcgcactggacacggcc
tgctcctccagcctgatggccctgcagaacgcctaccaggccatccacagcgggcagtgc
cctgccgccatcgtagggggcatcaacgtcctgctgaagcccaacacctccgtgcagttc
ttgaggctggggatgctcagccccgagggcacctgcaaggccttcgacacagcggggaat
gggtactgccgctcggagggtgtggtggccgtcctgctgaccaagaagtccctggcccgg
cgggtgtacgccaccatcctgaacgccggcaccaatacagatggcttcaaggagcaaggc
gtgaccttcccctcagggggtatccaggagcagctcatctgctcgttgtaccagtcggcc
ggagtggcccctgagtcatttgaatacatcgaagcccatggcacaggcaccaaggtgggc
gacccccaggagctgaatggcatcacccgagccctgtgcgccacccgccaggagccgctg
ctcatcggctccaccaagtccaacatggggcacccagagccagcctcggggctggcagcc
ctggccaaggtgctgctgtccctggagcacgggctctgggcccccaacctgcacttccat
agccccaaccctgagatcccagcgctgttggatgggcggctgcaggtggtggaccagccc
ctgcccgtccgtggcggcaacgtgggcatcaactcctttggcttcgggggctccaacgtg
cacgtcatcctgaggcccaacacgcagccgccccccgcacccgccccacacgccaccctg
ccccgtctgctgcgggccagcggacgcacccccgaggccgtgcagaagctgctggagcag
ggcctccggcacagccaggacctggctttcctgagcatgctgaacgacatcgcggctgtc
cccgccaccgccatgcccttccgtggctacgccgtgctgggtggtgagcacggtggccca
gaggtgcagcaggtgcccgctggcgagcgcccgctctggttcatctgctctgggatgggc
acacagtggcgcgggatggggctgagcctcatgcgcctggaccgcttccgagattccatc
ctacgctccgatgaggctgtgaagcctttcggcctgaaggtgtcacagctgctgctgagc
acagacgagagcacctttgatgacatcgtccattcgtttgtgagcctgactgccatccag
ataggcctcatagacctgctgagctgcatggggctgaggccagatggcatcgtcggccac
tccctgggggaggtggcctgtggctacgccgacggctgcctgtcccaggaggaggctgtc
ctcgctgcctactggaggggacagtgcatcaaagaagcccatctcccaccgggcgccatg
gcagccgtgggcttgtcctgggaggagtgtaaacagcgttgccccccgggcgtggtgccc
gcctgccacaactccaaggacacagtcaccatctcgggacctcaggccccagtgtttgag
ttcgtggagcagctgaggaaggagggtgtgttcgccaaggaggtgcggaccggcggtatg
gccttccactcctacttcatggaggccatcgcacccccactgctgcaggagctcaagaag
gtgatccgggagccgaagccacgttcagcccgctggctcagcacctctatccccgaggac
cagtggcacagcggcctggcacgcacgtcctccgccgagtacaatgtcaacaacctggtg
agccccgtgctgttccaggaggccctgtggcacgtgcctgagcacgcggtggtgctggag
atcgcgccccacgccctgctgcaggctgtcctgaagcgtggcctgaagccgagctgcacc
atcatccccctgatgaagaaggatcacagggacaacctggagttcttcctggccggcatc
ggcaggctgcacctctcaggcatcgacgccaaccccaatgccttgttcccgcctgtggag
ttcccagctccccgaggaactcccctcatctcccccctcatcaagtgggaccacagcctg
gcctgggacgtgccggccgccgaggacttccccaacggttctggttccccctcggccgcc
gtctacaacatcgacaccagctccgagtctcctgaccactacctggtggaccacaccctc
gacggtcgcgtcctcttccccgccactggctacctgagcatagtgtggaagacgctggcc
cgcgccctgggcctgggcgtcgagcagctgcccgtggtgtttgaggatgtggtgctgcac
caggccaccatcctgcccaagactgggacagtgtccctggaggtacggcttctggaggcc
tcccgcgccttcgaggtgtcagagaacggcaacctggtagtgagtgggaaggtgtaccag
tgggatgaccctgaccccaggctcttcgaccatccggaaagccccacccccaaccccgcg
gagcccctcttcctggcccaggctgaagtttacaaggagctgcgtctgcgcggctacgac
tacggccctcatttccagggcatcctggaggccagcctggaaggtgactcggggaggctg
ctgtggaaggataactgggtgagcttcgtggacaccatgctgcagatgtccatcctgggc
tcagccaagcacggcctgtacctgcccacccgtgtcaccgccatccacatcgaccctgcc
acccacaggcagaagctgtacacactgcaggacaaggcccaagtggctgacgtggtggtg
agcaggtggctgagggtcacagtggccggaggcgtccacatctccgggctccacactgag
tcggccccgcggcggcagcaggagcagcaggtgcccatcctggagaagttttgcttcact
ccccacatggaggaggggtgcctgtctgagcgcgctgccctgcaggaggagctgcaactg
tgcaaggggctggcacaggcactgcagaccaaggtgacccagcaggggctgaagatggtg
gtgcccggactggatggggcccagatcccccgggacccctcacagcaggaactgccccgg
ctgttgtcggctgcctgcaggcttcagctcaacgggaacctgcagctggagctggcgcag
gtgctggcccaggagaggcccaagctgccagaggaccctctgctcagcggcctcctggac
tccccggcactcaaggcctgcctggacactgccgtggagaacatgcccagcctgaagatg
aaggtggtggaggtgctggctggccacggtcacctgtattcccgcatcccaggcctgctc
agcccccatcccctgctgcagctgagctacacggccaccgaccgccacccccaggccctg
gaggctgcccaggccgagctgcagcagcacgacgttgcccagggccagtgggatcccgca
gaccctgcccccagtgccctgggcagcgccgacctcctggtgtgcaactgtgctgtggct
gccctcggagacccggcctcagctctcagcaacatggtggctgccctgagagaagggggc
tttctgctcctgcacacactgctccgggggcaccccctcggggacatcgtggccttcctc
acctccgctgagccgcagtacggccagggcatcctgagccaggacgcgtgggagagcctc
ttctccagggtgtcgctgcgcctggtgggcctgaagaagtccttctacggctccacgctc
ttcctgtgccgccggcccgccccgcaggacagccccatcttcctgccggtggacgatacc
agcttccgctgggtggagtctctgaagggcatcctggctgacgaagactcctcccggcct
gtgtggctgaaggccatcaactgtgccacctcgggtgtggtgggcttggtgaactgtctc
cgccgagagcctggcgggaaccgcctccggtgtgtgctgctctccaacctcagcagcacc
tcccacgtcccggaggtggacccgggctccgcagaactgcagaaggtgttgcagggagac
ctggtgatgaacgtctaccgcgacggggcctggggggctttccgccacttcctgctggag
gaggacaagcctgaggagccgacggcacacgcctttgtgaccaccctcacccggggggac
ctgtcctccatccgctgggtctgctcctcgctgcgccatgcccagcccacctgccctggc
gcccagctctgcacggtctactacgcctccctcaacttccgcgacatcatgctggccact
ggcaagctgtcccctgatgccatcccagggaagtggacctcccaggacagcctgctaggt
atggagttctcgggccgagacgccagcggcaagcgtgtgatgggactggtgcctgccaag
ggcctggccacctctgtcctgctgtcaccagacttcctctgggatgtgccttccaactgg
acgctggaggaggcggcctcggtgcctgtcgtctacagcacggcctactacgcgctggtg
gtgcgtgggcgggtgcgccccggggagacgctgctcatccactcgggctcgggcggcgtg
ggccaggccgccatcgccatcgccctcagtctgggctgccgcgtcttcaccaccgtgggg
tcggctgagaagcgggcgtacctccaggccaggttcccccagctcgacagcaccagcttc
gccaactcccgggacacatccttcgagcagcatgtgctgtggcacacgggcgggaagggc
gttgacctggtcttgaactccttggcggaagagaagctgcaggccagcgtgaggtgcttg
gctacgcacggtcgcttcctggaaattggcaaattcgacctttctcagaaccacccactc
ggcatggctatcttcctaaagaacgtgacattccacggggtcctgctggatgcgttcttc
aacgagagcagtgctgactggcgggaggtgtgggcgcttgtgcaggccggcatccgggat
ggggtggtacggcccctcaagtgcacggtgttccacggggcccaggtggaggaggccttc
cgctacatggcccaagggaagcacatcggcaaagtcgtcgtgcaggtgcttgcggaggag
ccggaggcagtgctgaagggggccaaacccaagctgatgtcggccatctccaagaccttc
tgcccggcccacaagagctacatcatcgctggtggtctgggtggcttcggcctggagttg
gcgcagtggctgatacagcgtggggtgcagaagctcgtgttgacttctcgctccgggatc
cggacaggctaccaggccaagcaggtccgccggtggaggcgccagggcgtacaggtgcag
gtgtccaccagcaacatcagctcactggagggggcccggggcctcattgccgaggcggcg
cagcttgggcccgtgggcggcgtcttcaacctggccgtggtcttgagagatgccctgctg
gagaaccagaccccagagttcttccaggacgtctgcaagcccaagtacagcggcaccctg
aacctggacagggtgacccgagaggcatgccctgagctggactactttgtggtcttctcc
tctgtgagctgcgggcgtggcaacgcgggacagagcaactacggctttgccaattccgcc
atggagcgtatctgtgagaaacgccggcacgaaggcctcccaggcctggccgtgcagtgg
ggcgccatcggcgacgtgggcattttggtggagacgatgagcaccaacgacacggtcgtc
actggcacgctgccccagcgcatggcgtcctgcctggaggtgctggacctcttcctgaac
cagccccacatggtcctgagcagctttgtgctggctgagaaggctgcggcctacagggac
agggacagccagcgggacctggtggaggccgtggcacacatcctgggcatccgcgacttg
gctgctgtcaacctggacagctcactggcggacctgggcctagactcgctcatgagcgtg
gaggtgcgccagacgctggagcgtgagctcaacctggtgctgtccgtgcgcgaggtgcgg
cagctcacgctccggaaactgcaggagctgtcctcaaaggcgggtgaggccaacgagctg
gcatgccccacgcccaaggaggatggtctggcccagcagcagactcagctgaacctgcgc
tccctgctggtgaacccggagggccccaccctgatgcggctcaactccgtgcagagctcg
gagcggcccctgttcctagtgcacccaatcgagggctccaccaccgtgttccacagcctg
gcctcccggctcagcatccccacctatggcctgcagtgcacccgagctgcgccccttgac
agcatccacagcctggctgcctactacatcgactgcatcaggcaggtgcagcccgagggc
ccctaccgtgtggccggctactcctacggggcctgcgtggcctttgaaatgtgctcccag
ctgcaggcccagcagagcccagcccccacccacaacagcctcttcctgttcgacggctcg
cccacctacgtactggcctacacccagagctaccgggcaaagctgaccccaggctgtgag
gccgaggccgagacggaggccgtatgcttcttcgtgcagcagttcacggacatggagcac
aacagggtgctggaggcgctgctgccgctgaagggcctagaggagcgtgtggcagccgcc
gtggacctgatcatcaagagccaccagggcctggaccgccaggagctgagctttgcggcc
cggtccttctactacaagctgcgtgccgctgagcagtacacacccaaggccaagtaccat
ggcaacgtgatgctactgcgcgccaagacgggtggcgcctacggcgaggacctgggcgcg
gactacaacctctcccaggtatgcgacgggaaagtatccgtccacgtcatcgagggtgac
caccgcacactgctggagggcagcggcctggagtccatcgtcagcatcatccacagctcc
ctggctgagccacgcgtgagcgtgcgggagggctag
DBGET
integrated database retrieval system
