Pan troglodytes (chimpanzee): 456565
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Entry
456565 CDS
T01005
Symbol
PIK3R3
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr01521
EGFR tyrosine kinase inhibitor resistance
ptr01522
Endocrine resistance
ptr01524
Platinum drug resistance
ptr04012
ErbB signaling pathway
ptr04014
Ras signaling pathway
ptr04015
Rap1 signaling pathway
ptr04024
cAMP signaling pathway
ptr04062
Chemokine signaling pathway
ptr04066
HIF-1 signaling pathway
ptr04068
FoxO signaling pathway
ptr04070
Phosphatidylinositol signaling system
ptr04071
Sphingolipid signaling pathway
ptr04072
Phospholipase D signaling pathway
ptr04081
Hormone signaling
ptr04140
Autophagy - animal
ptr04150
mTOR signaling pathway
ptr04151
PI3K-Akt signaling pathway
ptr04152
AMPK signaling pathway
ptr04210
Apoptosis
ptr04211
Longevity regulating pathway
ptr04213
Longevity regulating pathway - multiple species
ptr04218
Cellular senescence
ptr04360
Axon guidance
ptr04370
VEGF signaling pathway
ptr04380
Osteoclast differentiation
ptr04510
Focal adhesion
ptr04550
Signaling pathways regulating pluripotency of stem cells
ptr04611
Platelet activation
ptr04613
Neutrophil extracellular trap formation
ptr04620
Toll-like receptor signaling pathway
ptr04625
C-type lectin receptor signaling pathway
ptr04630
JAK-STAT signaling pathway
ptr04650
Natural killer cell mediated cytotoxicity
ptr04660
T cell receptor signaling pathway
ptr04662
B cell receptor signaling pathway
ptr04664
Fc epsilon RI signaling pathway
ptr04666
Fc gamma R-mediated phagocytosis
ptr04668
TNF signaling pathway
ptr04670
Leukocyte transendothelial migration
ptr04722
Neurotrophin signaling pathway
ptr04725
Cholinergic synapse
ptr04750
Inflammatory mediator regulation of TRP channels
ptr04810
Regulation of actin cytoskeleton
ptr04910
Insulin signaling pathway
ptr04914
Progesterone-mediated oocyte maturation
ptr04915
Estrogen signaling pathway
ptr04917
Prolactin signaling pathway
ptr04919
Thyroid hormone signaling pathway
ptr04923
Regulation of lipolysis in adipocytes
ptr04926
Relaxin signaling pathway
ptr04929
GnRH secretion
ptr04930
Type II diabetes mellitus
ptr04931
Insulin resistance
ptr04932
Non-alcoholic fatty liver disease
ptr04933
AGE-RAGE signaling pathway in diabetic complications
ptr04935
Growth hormone synthesis, secretion and action
ptr04960
Aldosterone-regulated sodium reabsorption
ptr04973
Carbohydrate digestion and absorption
ptr05010
Alzheimer disease
ptr05017
Spinocerebellar ataxia
ptr05020
Prion disease
ptr05100
Bacterial invasion of epithelial cells
ptr05135
Yersinia infection
ptr05142
Chagas disease
ptr05146
Amoebiasis
ptr05160
Hepatitis C
ptr05161
Hepatitis B
ptr05162
Measles
ptr05163
Human cytomegalovirus infection
ptr05164
Influenza A
ptr05165
Human papillomavirus infection
ptr05166
Human T-cell leukemia virus 1 infection
ptr05167
Kaposi sarcoma-associated herpesvirus infection
ptr05168
Herpes simplex virus 1 infection
ptr05169
Epstein-Barr virus infection
ptr05170
Human immunodeficiency virus 1 infection
ptr05171
Coronavirus disease - COVID-19
ptr05200
Pathways in cancer
ptr05203
Viral carcinogenesis
ptr05205
Proteoglycans in cancer
ptr05206
MicroRNAs in cancer
ptr05207
Chemical carcinogenesis - receptor activation
ptr05208
Chemical carcinogenesis - reactive oxygen species
ptr05210
Colorectal cancer
ptr05211
Renal cell carcinoma
ptr05212
Pancreatic cancer
ptr05213
Endometrial cancer
ptr05214
Glioma
ptr05215
Prostate cancer
ptr05218
Melanoma
ptr05220
Chronic myeloid leukemia
ptr05221
Acute myeloid leukemia
ptr05222
Small cell lung cancer
ptr05223
Non-small cell lung cancer
ptr05224
Breast cancer
ptr05225
Hepatocellular carcinoma
ptr05226
Gastric cancer
ptr05230
Central carbon metabolism in cancer
ptr05231
Choline metabolism in cancer
ptr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ptr05415
Diabetic cardiomyopathy
ptr05417
Lipid and atherosclerosis
ptr05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
456565 (PIK3R3)
04015 Rap1 signaling pathway
456565 (PIK3R3)
04630 JAK-STAT signaling pathway
456565 (PIK3R3)
04668 TNF signaling pathway
456565 (PIK3R3)
04066 HIF-1 signaling pathway
456565 (PIK3R3)
04068 FoxO signaling pathway
456565 (PIK3R3)
04070 Phosphatidylinositol signaling system
456565 (PIK3R3)
04072 Phospholipase D signaling pathway
456565 (PIK3R3)
04071 Sphingolipid signaling pathway
456565 (PIK3R3)
04024 cAMP signaling pathway
456565 (PIK3R3)
04151 PI3K-Akt signaling pathway
456565 (PIK3R3)
04152 AMPK signaling pathway
456565 (PIK3R3)
04150 mTOR signaling pathway
456565 (PIK3R3)
09133 Signaling molecules and interaction
04081 Hormone signaling
456565 (PIK3R3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
456565 (PIK3R3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
456565 (PIK3R3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
456565 (PIK3R3)
04613 Neutrophil extracellular trap formation
456565 (PIK3R3)
04620 Toll-like receptor signaling pathway
456565 (PIK3R3)
04650 Natural killer cell mediated cytotoxicity
456565 (PIK3R3)
04660 T cell receptor signaling pathway
456565 (PIK3R3)
04662 B cell receptor signaling pathway
456565 (PIK3R3)
04664 Fc epsilon RI signaling pathway
456565 (PIK3R3)
04666 Fc gamma R-mediated phagocytosis
456565 (PIK3R3)
04670 Leukocyte transendothelial migration
456565 (PIK3R3)
04062 Chemokine signaling pathway
456565 (PIK3R3)
09152 Endocrine system
04923 Regulation of lipolysis in adipocytes
456565 (PIK3R3)
04929 GnRH secretion
456565 (PIK3R3)
04915 Estrogen signaling pathway
456565 (PIK3R3)
04917 Prolactin signaling pathway
456565 (PIK3R3)
04926 Relaxin signaling pathway
456565 (PIK3R3)
04935 Growth hormone synthesis, secretion and action
456565 (PIK3R3)
04919 Thyroid hormone signaling pathway
456565 (PIK3R3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
456565 (PIK3R3)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
456565 (PIK3R3)
09156 Nervous system
04725 Cholinergic synapse
456565 (PIK3R3)
04722 Neurotrophin signaling pathway
456565 (PIK3R3)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
456565 (PIK3R3)
09158 Development and regeneration
04360 Axon guidance
456565 (PIK3R3)
04380 Osteoclast differentiation
456565 (PIK3R3)
09149 Aging
04211 Longevity regulating pathway
456565 (PIK3R3)
04213 Longevity regulating pathway - multiple species
456565 (PIK3R3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
456565 (PIK3R3)
05206 MicroRNAs in cancer
456565 (PIK3R3)
05205 Proteoglycans in cancer
456565 (PIK3R3)
05207 Chemical carcinogenesis - receptor activation
456565 (PIK3R3)
05208 Chemical carcinogenesis - reactive oxygen species
456565 (PIK3R3)
05203 Viral carcinogenesis
456565 (PIK3R3)
05230 Central carbon metabolism in cancer
456565 (PIK3R3)
05231 Choline metabolism in cancer
456565 (PIK3R3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
456565 (PIK3R3)
09162 Cancer: specific types
05210 Colorectal cancer
456565 (PIK3R3)
05212 Pancreatic cancer
456565 (PIK3R3)
05225 Hepatocellular carcinoma
456565 (PIK3R3)
05226 Gastric cancer
456565 (PIK3R3)
05214 Glioma
456565 (PIK3R3)
05221 Acute myeloid leukemia
456565 (PIK3R3)
05220 Chronic myeloid leukemia
456565 (PIK3R3)
05218 Melanoma
456565 (PIK3R3)
05211 Renal cell carcinoma
456565 (PIK3R3)
05215 Prostate cancer
456565 (PIK3R3)
05213 Endometrial cancer
456565 (PIK3R3)
05224 Breast cancer
456565 (PIK3R3)
05222 Small cell lung cancer
456565 (PIK3R3)
05223 Non-small cell lung cancer
456565 (PIK3R3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
456565 (PIK3R3)
05170 Human immunodeficiency virus 1 infection
456565 (PIK3R3)
05161 Hepatitis B
456565 (PIK3R3)
05160 Hepatitis C
456565 (PIK3R3)
05171 Coronavirus disease - COVID-19
456565 (PIK3R3)
05164 Influenza A
456565 (PIK3R3)
05162 Measles
456565 (PIK3R3)
05163 Human cytomegalovirus infection
456565 (PIK3R3)
05167 Kaposi sarcoma-associated herpesvirus infection
456565 (PIK3R3)
05169 Epstein-Barr virus infection
456565 (PIK3R3)
05165 Human papillomavirus infection
456565 (PIK3R3)
09171 Infectious disease: bacterial
05135 Yersinia infection
456565 (PIK3R3)
05100 Bacterial invasion of epithelial cells
456565 (PIK3R3)
09174 Infectious disease: parasitic
05146 Amoebiasis
456565 (PIK3R3)
05142 Chagas disease
456565 (PIK3R3)
09164 Neurodegenerative disease
05010 Alzheimer disease
456565 (PIK3R3)
05017 Spinocerebellar ataxia
456565 (PIK3R3)
05020 Prion disease
456565 (PIK3R3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
456565 (PIK3R3)
05418 Fluid shear stress and atherosclerosis
456565 (PIK3R3)
05415 Diabetic cardiomyopathy
456565 (PIK3R3)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
456565 (PIK3R3)
04932 Non-alcoholic fatty liver disease
456565 (PIK3R3)
04931 Insulin resistance
456565 (PIK3R3)
04933 AGE-RAGE signaling pathway in diabetic complications
456565 (PIK3R3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
456565 (PIK3R3)
01524 Platinum drug resistance
456565 (PIK3R3)
01522 Endocrine resistance
456565 (PIK3R3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ptr04131
]
456565 (PIK3R3)
Membrane trafficking [BR:
ptr04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
456565 (PIK3R3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
SH2_1
Transcrip_act
Cupin_8
Exonuc_VII_L
Motif
Other DBs
NCBI-GeneID:
456565
NCBI-ProteinID:
XP_016817599
Ensembl:
ENSPTRG00000000685
VGNC:
11765
LinkDB
All DBs
Position
1:184789182..184923922
Genome browser
AA seq
417 aa
AA seq
DB search
MTSAVPNGMKDSSVSLQDAEWYWGDISREEVNDKLRDMPDGTFLVRDASTKMQGDYTLTL
RKGGNNKLIKIYHRDGKYGFSDPLTFNSVVELINHYHHESLAQYNPKLDVKLMYPVSRYQ
QDQLVKEDNIDAVGKKLQEYHSQYQEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIK
IFEEQCHTQEQHSKEYIERFRREGNEKEIERIMMNYDKLKSRLGEIHDSKMRLEQDLKKQ
ALDNREIDKKMNSIKPDLIQLRKIRDQHLVWLNHKGVRQKRLNVWLGIKNEDADENYFIN
EEDENLPHYDEKTWFVEDINRVQAEDLLYGKPDGAFLIRESSKKGCYACSVVADGEVKHC
VIYSTARGYGFAEPYNLYSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQMPSLCR
NT seq
1254 nt
NT seq
+upstream
nt +downstream
nt
atgacttcagcagttccaaatggaatgaaggacagttctgtttctcttcaggatgcagaa
tggtactggggggatatttcaagggaggaggtaaatgacaaattgcgggatatgccagat
gggaccttcttggtccgagatgcctcaacaaaaatgcagggagattatactttgactttg
cggaagggaggcaataataagttaataaagatctatcaccgggatggtaaatatggcttt
tctgatcctctgacatttaattccgtggtggagctcattaaccactatcaccatgaatct
cttgctcagtacaatcccaaacttgatgtgaagctgatgtacccagtgtccagataccaa
caggatcagttggtaaaagaagataatattgatgcagtaggtaaaaaactgcaagaatac
cactctcagtatcaggagaagagtaaagagtatgataggctgtatgaagaatatactaga
acatcccaggaaatacagatgaagaggactgcaatagaagcttttaatgaaacaattaaa
atatttgaagagcagtgtcacacacaagaacaacatagcaaagaatatattgagcgattt
cgcagagaggggaatgaaaaggagattgaacgaattatgatgaattatgataaattgaaa
tcacgtctgggagagattcatgatagcaaaatgcgtctagagcaggatttgaagaaacaa
gctttggacaaccgagaaatagataaaaaaatgaatagtatcaaacctgacctgatccag
ctgcgaaagatccgagatcaacaccttgtatggctcaatcacaaaggagtgagacagaaa
cgcctgaatgtctggctgggaattaagaatgaggatgctgatgagaactattttatcaat
gaggaagatgaaaacctgccccattatgatgagaaaacctggtttgttgaggatatcaat
cgagtacaagcagaggacttgctttatgggaaacctgatggtgcattcttaattcgtgag
agtagcaagaaaggatgctatgcttgctctgtggtggccgatggggaagtgaagcactgt
gtgatctacagcactgctcggggctatggctttgcagagccctacaacctgtacagctct
ctgaaggagctagtgctccattaccagcagacatccttggttcagcacaacgactccctc
aacgtcaggcttgcctaccctgttcatgcacagatgccctcgctttgcagataa
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integrated database retrieval system
