Pan troglodytes (chimpanzee): 457169
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Entry
457169 CDS
T01005
Symbol
HMGCS2
Name
(RefSeq) hydroxymethylglutaryl-CoA synthase, mitochondrial
KO
K01641
hydroxymethylglutaryl-CoA synthase [EC:
2.3.3.10
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00280
Valine, leucine and isoleucine degradation
ptr00650
Butanoate metabolism
ptr00900
Terpenoid backbone biosynthesis
ptr01100
Metabolic pathways
ptr03320
PPAR signaling pathway
Module
ptr_M00095
C5 isoprenoid biosynthesis, mevalonate pathway
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
457169 (HMGCS2)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
457169 (HMGCS2)
09109 Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
457169 (HMGCS2)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
457169 (HMGCS2)
Enzymes [BR:
ptr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.10 hydroxymethylglutaryl-CoA synthase
457169 (HMGCS2)
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GFIT
Motif
Pfam:
HMG_CoA_synt_C
HMG_CoA_synt_N
ACP_syn_III
Motif
Other DBs
NCBI-GeneID:
457169
NCBI-ProteinID:
XP_513693
Ensembl:
ENSPTRG00000001179
VGNC:
6865
UniProt:
A0A6D2YC48
A0A2J8JUL8
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Position
1:complement(116947471..116968126)
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AA seq
508 aa
AA seq
DB search
MQRLLTPVKRILQLTRAVQETSLTPARLLPVAHQRFSTASAVPLAKTDTWPKDVGILALE
VYFPAQYVDQTDLEKYNNVEAGKYTVGLGQTHMGFCSVQEDINSLCLTVVQRLMERIQLP
WDSVGRLEVGTETIIDKSKAVKTVLMELFQDSGNTDIEGIDTTNACYGGTASLFNAANWM
ESSSWDGRYAMVVCGDIAVYPSGNARPTGGAGAVAMLIGPKAPLALERGLRGTHMENAYD
FYKPNLASEYPIVDGKLSIQCYLRALDRCYTSYRKKIQNQWKQAGSDRPFTLDDLQYMIF
HTPFCKMVQKSLARLMFNDFLSASSDTQTSLYKGLEAFGGLKLEDTYTNKDLDKALLKAS
QDMFDKKTKASLYLSTHNGNMYTSSLYGCLASLLSHHSAQELAGSRIGAFSYGSGLAASF
FSFRVSQDAAPGSPLDKLVSSTSDLPKRLASRKCVSPEEFTEIMNQREQFYHKVNFSPPG
DTNSLFPGTWYLERVDEQHRRKYARRPV
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgcagcgtctgttgactccagtgaagcgcattctgcaactgacaagagcggtgcaggaa
acctccctcacccctgctcgcctgctcccagtagcccaccaaaggttttctacagcctct
gctgtccccctggccaaaacagatacttggccaaaggacgtgggcatcctggccctggag
gtctacttcccagcccaatatgtggaccaaactgacctggagaagtataacaatgtggaa
gcaggaaagtatacagtgggcttgggccagacccatatgggcttctgctcagtccaagag
gacatcaactccctgtgcctgacagtggtgcaacggctgatggagcgcatacagctccca
tgggactctgtgggcaggctggaagtaggcactgagaccatcattgacaagtccaaagct
gtcaaaacagtgctcatggaactcttccaggattcaggcaatactgatattgagggcata
gataccaccaatgcctgctacggtggtactgcctccctcttcaatgctgccaactggatg
gagtccagttcctgggatggtcgttatgccatggtggtctgtggagacattgccgtctat
cccagtggtaatgctcgtcccacaggtggggccggagctgtggctatgctgattgggccc
aaggcccctctggccctggagcgagggctgaggggaacccatatggagaatgcgtatgac
ttctacaaaccaaatttggcctcggagtacccaatagtggatgggaagctttccatccag
tgctacttgcgggccttggatcgatgttacacatcataccgtaaaaaaatccagaatcag
tggaagcaagctggcagcgatcgacccttcacccttgacgatttacagtacatgatcttt
catacacccttttgcaagatggtccagaagtctctggctcgcctgatgttcaatgacttc
ctgtcagccagcagtgacacacaaaccagcttatataaggggctggaggctttcgggggg
ctaaagctggaagacacctacaccaacaaggacctggataaagcacttctaaaggcctct
caggacatgttcgacaagaaaaccaaggcttccctttacctctccacgcacaatgggaac
atgtacacctcatccctgtacgggtgcctggcctcgcttctgtcccaccactctgcccag
gaactggctggctccaggattggtgccttctcttatggctctggtttagcagcaagtttc
ttttcatttcgagtatcccaggatgctgctccaggctctcccctggacaagttggtgtcc
agtacatcagacctgccaaaacgcctagcctcccgaaagtgtgtgtctcctgaggagttc
acagaaataatgaaccaaagagagcaattctaccataaggtgaatttctccccacctggt
gacacaaacagccttttcccaggtacttggtacctggagcgagtggacgagcagcatcgc
cgaaagtatgcccggcgtcccgtctaa
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