Pan troglodytes (chimpanzee): 459127
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Entry
459127 CDS
T01005
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor isoform X1
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr05200
Pathways in cancer
ptr05223
Non-small cell lung cancer
ptr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
459127 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
459127 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
459127 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
459127 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ptr04090
]
459127 (ALK)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
459127 (ALK)
Protein kinases [BR:
ptr01001
]
Receptor tyrosine kinases (RTK)
ALK family
459127 (ALK)
CD molecules [BR:
ptr04090
]
Proteins
459127 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
MAM
ALK_LTK_GRD
Ldl_recept_a
Nup96
FXa_inhibition
Motif
Other DBs
NCBI-GeneID:
459127
NCBI-ProteinID:
XP_016803770
Ensembl:
ENSPTRG00000011796
VGNC:
10681
UniProt:
H2QHP7
LinkDB
All DBs
Position
12:92920858..93657767
Genome browser
AA seq
1620 aa
AA seq
DB search
MGAIGLLWLLPLLLSTAAVGSGMGTGQRAGSPAARPPLQPREPLSYSRLQRKSLAVDFVV
PSLFRVYARDLLLPPSSSELKAGRPEARGSLALDCAPLLRLLGPAPGVSWTAGSPAPAEA
RTLSRVLKGGSVRKLRRAKQLVLELGEEAILEGCVGPPGEAAVGLLQFNLSELFSWWIRQ
GEGRLRIRLMPEKKASEVGREGRLSAAIRASQPRLLFQIFGTGHSSLESPTNMPSPSPDY
FTWNLTWIMKDSFPFLSHRSRYGLECSFDFPCELEYSPPLHDLRNQSWSWRRVPSEEASQ
MDLLDGPGAERSKEMPRGSFLLLNTSADSKHTILSPWMRSSSEHCTLAVSVHRHLQPSGR
YIAQLLPHNEAAREILLMPTPGKHGWTVLQGRIGRPDNPFRVALEYISSGNRSLSAVDFF
ALKNCSEGTSPGSKMALQSSFTCWNGTVLQLGQACDFHQDCAQGEDESQMCRKLPVGFYC
NFEDGFCGWTQDTLSPHTPQWQVRTLKDARFQDHQDHALLLSTTDVPTSESATVTSATFP
APIKSSPCELRMSWLIRGVLRGNVSLVLVENKTGKEQGRMVWHVAAYEGLSLWQWTVLPL
LDVSDRFWLRMVAWWGQGSRAIVAFDNISISLDCYLTISGEDKILQNTAPKSRNLFERNP
NKELKPGENSPRQTPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVEVGSEGPL
KGIQIWKVPATDTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGE
DACPSTNQLIQKVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLII
AAGGGGRAYGAKTDTFHPERLENNSSVLGLNGNSGAAGGGGGWNDNTSLLWAGKSLQEGA
TGGHSCPQAMKKWGWETRGGFGGGGGGCSSGGGGGGYIGGNAASNNDPEMDGEDGVSFIS
PLGILYTPALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVS
CIVSPTPEPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKL
SKLRTSTIMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPN
DPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMA
GGDLKSFLRETRPRPSQPTSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCP
GPGRVAKIGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLW
EIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPTFAIIL
ERIEYCTQDPDVINTALPIEYGPLVEEEEKVPVRPKDPEGVPPLLVSQQAKREEERSPAA
PPPLPTTSSGKAAKKPTAAEVSVRVPRGPAVEGGHVNMAFSQSNPPSELHKVHGSRNKPT
SLWNPTYGSWFTEKPTKKNNPIAKKEPHERGNLGLEGSCTVPPNVATGRLPGASLLLEPS
SLTANMKEVPLFRLRHFPCGNVNYGYQQQGLPLEAATAPGAGHYEDTILKSKNSMNQPGP
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atgggagccatcgggctcctgtggctgctgccgctgctgctttccacggcagctgtgggc
tccgggatggggaccggccagcgcgcgggctccccagctgcgaggccgccgctgcagccc
cgggagccactcagctactcgcgcctgcagaggaagagtctggcagttgacttcgtggtg
ccctcgctcttccgtgtctacgcccgggacctactgctgccaccatcctcctcggagctg
aaggctggcaggcccgaggcgcgcggctcgctagctctggactgcgccccgctgctcagg
ttgctggggccggcgccgggggtctcctggaccgccggttcaccagccccggcagaggcc
cggacgctgtccagggtgctgaagggcggctccgtgcgcaagctccggcgtgccaagcag
ttggtgctggagctgggcgaggaggcgatcttggagggttgcgtcgggccccccggggag
gcagctgtggggctgctccagttcaatctcagcgagctgttcagttggtggattcgccaa
ggcgaagggcgactgaggatccgcctgatgcccgagaagaaggcgtcggaagtgggcaga
gagggaaggctgtccgcggcaattcgcgcctcccagccccgccttctcttccagatcttc
gggactggtcatagctccttggaatcaccaacaaacatgccttctccttctcctgattat
tttacatggaatctcacctggataatgaaagactccttccctttcctgtctcatcgcagc
cgatatggtctggagtgcagctttgacttcccctgtgagctggaatattcccctccactg
catgacctcaggaaccagagctggtcctggcgccgcgtcccctccgaggaggcctcccag
atggacttgctggatgggcctggggcggagcgttctaaggagatgcccagaggctccttt
ctccttctcaacacctcagctgactccaagcacaccatcctgagtccgtggatgaggagc
agcagtgagcactgcacactggccgtctcggtgcacaggcacctgcagccctctggaagg
tacattgcccagctgctgccccacaacgaggctgcaagagagatcctcctgatgcccact
ccagggaagcatggttggacagtgctccagggaagaatcgggcgcccagacaacccgttt
cgagtggccctggaatacatctccagtggaaaccgcagcttgtctgcagtggacttcttt
gccctgaagaactgcagtgaaggaacatccccaggctccaagatggccctgcagagctcc
ttcacttgttggaatgggacagtcctccagcttgggcaggcctgtgacttccaccaggac
tgtgcccagggagaagatgagagccagatgtgccggaaactgcctgtcggtttttactgc
aactttgaagatggcttctgtggctggacccaagacacactgtcaccccacactcctcaa
tggcaggtcaggaccctaaaggatgcccggttccaggaccaccaagaccatgctctattg
ctcagtaccactgatgtccccacttctgaaagtgctacagtgaccagtgctacgtttcct
gcaccgatcaagagctctccatgtgagctccgaatgtcctggctcattcgtggagtcttg
aggggaaacgtgtccttggtgctagtggagaacaaaaccgggaaggagcaaggcaggatg
gtctggcatgtcgccgcctatgaaggcttgagcctgtggcagtggacggtgttgcctctc
ctcgatgtgtctgacaggttctggctgcggatggtcgcatggtggggacaaggatccaga
gccatcgtggcttttgacaatatctccatcagcctggactgctacctcaccattagtgga
gaggacaagatcctgcagaatacagcacccaaatcaagaaacctgtttgagagaaaccca
aacaaggagctgaaacccggggaaaattcaccaagacagacccccatctttgaccctaca
gttcattggctgttcaccacctgtggggccagcgggccccatggccccacccaggcacag
tgcaacaacgcctaccagaactccaacctgagcgtggaggtggggagcgagggccccctg
aaaggcatccagatctggaaggtgccagccaccgacacctacagcatctcgggctacgga
gctgctggcgggaaaggcgggaagaacaccatgatgcggtcccacggcgtgtctgtgctg
ggcatcttcaacctggagaaggatgacatgctgtacatcctggttgggcagcagggagag
gacgcctgccccagtacaaaccagttaatccagaaagtctgcattggagagaacaatgtg
atagaagaagaaatccgtgtgaacagaagcgtgcatgagtgggcaggaggcggaggagga
gggggtggagccacctacgtatttaagatgaaggatggagtgccggtgcccctgatcatt
gcagccggaggtggcggcagggcctacggggccaagacagacacgttccacccagagaga
ctggagaataactcctcggttctagggctaaacggcaattccggagccgcaggtggtgga
ggtggctggaatgataacacttccttgctctgggccggaaaatctttgcaggagggtgcc
accggaggacattcctgcccccaggccatgaagaagtgggggtgggagacaagagggggt
ttcggagggggtggaggggggtgctcctcaggtggaggaggcggaggatatataggcggc
aatgcagcctcaaacaatgaccccgaaatggatggggaagatggggtttccttcatcagt
ccactgggcatcctgtacaccccagctttaaaagtgatggaaggccacggggaagtgaat
attaagcattatctaaactgcagtcactgtgaggtagacgaatgtcacatggaccctgaa
agccacaaggtcatctgcttctgtgaccacgggacggtgctggctgaggatggcgtctcc
tgcatcgtgtcacccaccccggagccacacctgccactctcgctgatcctctctgtggtg
acctctgccctcgtggccgccctggtcctggctttctccggcatcatgattgtgtaccgc
cggaagcaccaggagctgcaagccatgcagatggagctgcagagccctgagtacaagctg
agcaagctccgcacctcgaccatcatgaccgactacaaccccaactactgctttgccggc
aagacctcctccatcagtgacctgaaggaggtgccgcggaaaaacatcaccctcattcgg
ggtctgggccatggcgcctttggggaggtgtatgaaggccaggtgtccggaatgcccaac
gacccaagccccctgcaagtggctgtgaagacgctgcctgaagtgtgctctgaacaggat
gaactggatttcctcatggaagccctgatcatcagcaaattcaaccaccagaacatcgtt
cgctgcattggggtgagcctgcaagccctgccccggttcatcctgctggagctcatggcg
gggggagacctcaagtccttcctccgagagacccgccctcgcccgagccagcccacctcc
ctggccatgctggaccttctgcacgtggctcgggacattgcctgtggctgtcagtatttg
gaggaaaaccacttcatccaccgagacattgctgccagaaactgcctcttgacctgtcca
ggccctggaagagtggccaagattggagacttcgggatggcccgagacatctacagggcg
agctactatagaaagggaggctgtgccatgctgccagttaagtggatgcccccagaggcc
ttcatggaaggaatattcacttctaaaacagacacatggtcctttggagtgctgctatgg
gaaatcttttctctcggatatatgccataccccagcaaaagcaaccaggaagttctggag
tttgtcaccagtggaggccggatggacccacccaagaactgccctgggcctgtataccgg
ataatgactcagtgctggcaacatcagccggaagacaggcccacctttgccatcattttg
gagaggattgaatactgcacccaggacccggatgtaatcaacaccgctttgccgatagaa
tatggtccacttgtggaagaggaagagaaagtgcctgtgaggcccaaggaccctgagggg
gttcctcctctcctggtctctcaacaggcgaaacgcgaggaggagcgcagcccagctgcc
ccaccacctctgcctaccacctcctctggcaaggctgcaaagaaacccacagctgcagag
gtctctgttcgagtccctagagggccggccgtggaagggggacacgtgaatatggcattc
tctcagtccaaccccccttcggagttgcacaaggtccacggatccagaaacaagcccacc
agcttgtggaacccaacgtacggctcctggtttacagagaaacccaccaaaaagaataat
cctatagcaaagaaggagccacacgagaggggtaacctggggctggagggaagctgtact
gtcccacctaacgttgcaactgggagacttccgggggcctcactgctcctagagccctct
tcgctgactgccaatatgaaggaggtacctctgttcaggctacgtcacttcccttgtggg
aatgtcaattacggctaccagcaacagggcttgcccttagaagccgctactgcccctgga
gctggtcattacgaggataccattctgaaaagcaagaatagcatgaaccagcctgggccc
tga
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integrated database retrieval system
